Search Results - "Upadhyay, Vivek A."
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Multicenter analysis of outcomes in blastic plasmacytoid dendritic cell neoplasm offers a pretargeted therapy benchmark
Published in Blood (22-08-2019)“…Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an uncommon hematologic malignancy with poor outcomes. Existing data on the clinical behavior of BPDCN…”
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Utilizing a PLASMIC score‐based approach in the management of suspected immune thrombotic thrombocytopenic purpura: a cost minimization analysis within the Harvard TMA Research Collaborative
Published in British journal of haematology (01-08-2019)“…Summary The PLASMIC score is a recently described clinical scoring algorithm that rapidly assesses the probability of severe ADAMTS13 (a disintegrin and…”
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Predictors of relapse and efficacy of rituximab in immune thrombotic thrombocytopenic purpura
Published in Blood advances (14-05-2019)“…Patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP) often experience life-threatening relapses of the disease, and rituximab (RTX) can be…”
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Isocitrate dehydrogenase (IDH) inhibition as treatment of myeloid malignancies: Progress and future directions
Published in Pharmacology & therapeutics (Oxford) (01-09-2017)“…Isocitrate dehydrogenase (IDH) is an essential metabolic enzyme. Over the last two decades, there has been a growing focus on the metabolic derangements that…”
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Induction chemotherapy in acute myeloid leukaemia: origins and emerging directions
Published in Current opinion in hematology (01-03-2018)“…PURPOSE OF REVIEWThis review summarizes the hallmark developments in induction chemotherapy for acute myeloid leukaemia and further describes future directions…”
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Real-World Analysis of Off-Label Use of Molecularly Targeted Therapy in a Large Academic Medical Center Cohort
Published in JCO precision oncology (01-01-2022)“…The primary objective of this study is to quantify the use of off-label molecularly targeted therapy and describe the clinical situations in which off-label…”
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Genomic Profiling of Combined Hepatocellular Cholangiocarcinoma Reveals Genomics Similar to Either Hepatocellular Carcinoma or Cholangiocarcinoma
Published in JCO precision oncology (01-08-2021)“…Combined hepatocellular cholangiocarcinoma (cHCC-CCA) is a rare, aggressive primary liver carcinoma, with morphologic features of both hepatocellular…”
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The Approach to Acute Lymphoblastic Leukemia in Older Patients: Conventional Treatments and Emerging Therapies
Published in Current hematologic malignancy reports (01-06-2016)“…Acute lymphoblastic leukemia (ALL) among older adult patients presents significant clinical challenges. As opposed to pediatric populations, in whom long-term…”
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Predictors of Relapse and Efficacy of Rituximab in Autoimmune Thrombotic Thrombocytopenic Purpura (TTP): A Multi-Institutional Registry-Based Analysis
Published in Blood (29-11-2018)“…Introduction: Thrombotic thrombocytopenic purpura (TTP) is a distinct and lethal subtype of thrombotic microangiopathy (TMA) requiring treatment with…”
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Projected Cost Savings of a Plasmic Score-Based Approach to Patients with Suspected Thrombotic Thrombocytopenic Purpura
Published in Blood (08-12-2017)“…Background: Thrombotic thrombocytopenic purpura (TTP) is a rare but deadly thrombotic microangiopathy (TMA) that is caused by a severe acquired deficiency in…”
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