Search Results - "Upadhyay, Sunil P"
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Chalcone and its analogs: Therapeutic and diagnostic applications in Alzheimer’s disease
Published in Bioorganic chemistry (01-03-2021)“…[Display omitted] Chalcone [(E)-1,3-diphenyl-2-propene-1-one], a small molecule with α, β unsaturated carbonyl group is a precursor or component of many…”
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pH-responsive targeted nanoparticles release ERK-inhibitor in the hypoxic zone and sensitize free gemcitabine in mutant K-Ras-addicted pancreatic cancer cells and mouse model
Published in PloS one (30-04-2024)“…Therapeutic options for managing Pancreatic ductal adenocarcinoma (PDAC), one of the deadliest types of aggressive malignancies, are limited and disappointing…”
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Single-Molecule Investigation of Initiation Dynamics of an Organometallic Catalyst
Published in Journal of the American Chemical Society (23-03-2016)“…The action of molecular catalysts comprises multiple microscopic kinetic steps whose nature is of central importance in determining catalyst activity and…”
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Chalcone: A potential scaffold for NLRP3 inflammasome inhibitors
Published in European journal of medicinal chemistry reports (01-04-2023)“…Overactivated NLRP3 inflammasome has been shown to associate with an increasing number of disease conditions. Activation of the NLRP3 inflammasome results in…”
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Benefits and Pitfalls of a Glycosylation Inhibitor Tunicamycin in the Therapeutic Implication of Cancers
Published in Cells (Basel, Switzerland) (25-02-2024)“…The aberrant glycosylation is a hallmark of cancer progression and chemoresistance. It is also an immune therapeutic target for various cancers. Tunicamycin…”
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Ion Transport in Solvent-Free, Crosslinked, Single-Ion Conducting Polymer Electrolytes for Post-Lithium Ion Batteries
Published in Batteries (Basel) (01-06-2018)“…Solvent-free, single-ion conducting electrolytes are sought after for use in electrochemical energy storage devices. Here, we investigate the ionic…”
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Cross-Linked Ionomer Gel Separators for Polysulfide Shuttle Mitigation in Magnesium–Sulfur Batteries: Elucidation of Structure–Property Relationships
Published in Macromolecules (13-11-2018)“…Cross-linked ionomer networks of varying poly(ethylene glycol) diacrylate cross-linker chain length, ionic comonomer chemistry, and comonomer ratio have been…”
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Influence of ligand geometry on cholinesterase enzyme - A comparison of 1-isoindolinone based structural analog with Donepezil
Published in Journal of molecular structure (05-01-2022)“…•Donepezil and compound #20 along with other 24 compounds were evaluated on physicochemical characteristics, cytotoxicity, cell proliferation effect, BuChE and…”
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1-Isoindolinone scaffold-based natural products with a promising diverse bioactivity
Published in Fitoterapia (01-10-2020)“…Isoindolin-1-one or 1-isoindolinone framework is referred to phthalimidines or benzo fused γ-lactams of the corresponding γ-amino carboxylic acids and has been…”
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Fluorescent Dendrimeric Molecular Catalysts Demonstrate Unusual Scaling Behavior at the Single-Molecule Level
Published in Journal of physical chemistry. C (27-08-2015)“…A series of surface-supported molecular palladium catalysts were synthesized using a dendrimeric attachment motif to incorporate multiple BODIPY fluorophores…”
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Correction to “Fluorescent Dendrimeric Molecular Catalysts Demonstrate Unusual Scaling Behavior at the Single-Molecule Level”
Published in Journal of physical chemistry. C (05-11-2015)Get full text
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Furo-Fused BINOL Based Crown as a Fluorescent Chiral Sensor for Enantioselective Recognition of Phenylethylamine and Ethyl Ester of Valine
Published in Journal of organic chemistry (20-07-2007)“…A furo-fused BINOL based chiral crown was developed as an enantioselective chiral sensor for phenylethylamine and ethyl ester of valine. Fusion of furan to…”
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Tracking Lithium Ions via Widefield Fluorescence Microscopy for Battery Diagnostics
Published in ACS sensors (28-07-2017)“…Direct tracking of lithium ions with time and spatial resolution can provide an important diagnostic tool for understanding mechanisms in lithium ion…”
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[9,9′]Bi[naphtho(2,1- b)furanyl]-8,8′-diol, a furo-fused BINOL derivative: synthesis, resolution and determination of absolute configuration
Published in Tetrahedron: asymmetry (18-04-2006)“…A high yielding synthetic protocol was employed in order to achieve the placement of a furan ring at the most sterically crucial position of BINOL to obtain…”
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Enantioselective synthesis of ( R) and ( S)-[9,9′]bi[naphtho(2,1- b)furanyl]-8,8′-diol: a furo-fused BINOL derivative
Published in Tetrahedron letters (2007)“…The enantioselective synthesis of [9,9′]bi[naphtho(2,1- b)furanyl]-8,8′-diol, a modified BINOL, was achieved using an inexpensive route. Both enantiomers of…”
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