Search Results - "Upadhyay, Shivbrat"
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Cytostatic and Anti-tumor Potential of Ajwa Date Pulp against Human Hepatocellular Carcinoma HepG2 Cells
Published in Scientific reports (21-01-2019)“…Ajwa dates ( Phoenix dactylifera L.) are used by traditional therapeutic practitioners for several health benefits but most remain to be scientifically…”
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Exploring the ROS-mediated anti-cancer potential in human triple-negative breast cancer by garlic bulb extract: A source of therapeutically active compounds
Published in Journal of Traditional and Complementary Medicine (01-11-2024)“…Background and aim: Allium sativum L. has been used medicinally and traditionally since antiquity. This study sought to examine the Allium sativum ethanolic…”
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The relationship between MMP-2 rs243865, MMP-9 rs398242 and CXCL-12 rs1801157 gene polymorphisms with Japanese encephalitis disease and disease outcome in North Indian population
Published in Journal of vector borne diseases (01-01-2023)“…Background & objectives: Japanese encephalitis virus (JEV) is one of the most important causes of acute and uncontrolled inflammatory disease in Asia. Matrix…”
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Anticancer potential of Phoenix dactylifera L. seed extract in human cancer cells and pro-apoptotic effects mediated through caspase-3 dependent pathway in human breast cancer MDA-MB-231 cells: an in vitro and in silico investigation
Published in BMC complementary medicine and therapies (15-03-2022)“…Phoenix dactylifera L. has a diverse set of pharmacological properties due to its distinct phytochemical profile. The purpose of this study was to investigate…”
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Cytotoxicity of Moringa oleifera fruits on human liver cancer and molecular docking analysis of bioactive constituents against caspase‐3 enzyme
Published in Journal of food biochemistry (01-05-2021)“…Moringa oleifera is an excellent source of phenolics and flavonoids comprise various pharmacological activities. The fourth widespread leading cause of the…”
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Virtual screening of phytoconstituents from miracle herb nigella sativa targeting nucleocapsid protein and papain-like protease of SARS-CoV-2 for COVID-19 treatment
Published in Journal of biomolecular structure & dynamics (01-06-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel etiological agent of coronavirus disease 2019 (COVID-19). Nigella sativa, commonly…”
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Pro-inflammatory and anti-inflamatory cytokine genes polymorphisms and susceptibility to Japanese encephalitis disease in the North Indian population
Published in Cytokine (Philadelphia, Pa.) (01-01-2022)“…•Host innate immune responses are related with disease severity in JE diseases.•IL-1β and IL-10 gene polymorphism lead to increased proinflammatory response in…”
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Differential expression of circulating microRNAs in serum: Potential biomarkers to track Japanese encephalitis virus infection
Published in Journal of medical virology (01-02-2022)“…Japanese encephalitis is one of the serious vector‐borne viral encephalitis diseases found worldwide and poses a major threat to public health. Most Japanese…”
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Interaction of Bioactive Compounds of Moringa oleifera Leaves with SARS-CoV-2 Proteins to Combat COVID-19 Pathogenesis: a Phytochemical and In Silico Analysis
Published in Applied biochemistry and biotechnology (01-12-2022)“…Novel SARS-CoV-2 claimed a large number of human lives. The main proteins for viral entry into host cells are SARS-CoV-2 spike glycoprotein (PDB ID: 6VYB) and…”
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Prophylactic and therapeutic potential of selected immunomodulatory agents from Ayurveda against coronaviruses amidst the current formidable scenario: an in silico analysis
Published in Journal of biomolecular structure & dynamics (01-01-2022)“…There is currently a dearth of specific therapies to treat respiratory infections caused by the three related species of coronaviruses viz. SARS-CoV-2,…”
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Structural interactions of phytoconstituent(s) from cinnamon, bay leaf, oregano, and parsley with SARS‐CoV‐2 nucleocapsid protein: A comparative assessment for development of potential antiviral nutraceuticals
Published in Journal of food biochemistry (01-10-2022)“…SARS‐CoV‐2 has been responsible for causing 6,218,308 deaths globally till date and has garnered worldwide attention. The lack of effective preventive and…”
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Steroidal lactones from Withania somnifera effectively target Beta, Gamma, Delta and Omicron variants of SARS-CoV-2 and reveal a decreased susceptibility to viral infection and perpetuation: a polypharmacology approach
Published in In silico pharmacology (27-02-2024)“…Prevention from disease is presently the cornerstone of the fight against COVID-19. With the rapid emergence of novel SARS-CoV-2 variants, there is an urgent…”
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Isolation, identification and screening of soil fungi for production of extra cellular protease and amylase
Published in Journal of natural science, biology and medicine (01-12-2011)“…Soil fungi are microscopic plant-like cells, which enlarges, colonize the soil and produce water stable aggregates that link up as macro-aggregates to maximize…”
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