Search Results - "Upadhyay, Sandeep"
-
1
LC3-associated phagocytosis: host defense and microbial response
Published in Current opinion in immunology (01-10-2019)“…•LC3-associated phagocytosis (LAP) and xenophagy target microbes for lysosomal destruction.•LAP and xenophagy not only make use of shared components but also…”
Get full text
Journal Article -
2
Opportunistic screening for detection and socio-epidemiological risk assessment of oral cancer patients in rural Jodhpur, India
Published in Indian journal of medical and paediatric oncology (01-10-2018)“…Background: Globally, India has a high burden (20%) of oral cancer with 1% prevalence of premalignant lesions. Most cases are attributed to modifiable risk…”
Get full text
Journal Article -
3
Phosphorylation of Mycobacterium tuberculosis Ser/Thr phosphatase by PknA and PknB
Published in PloS one (09-03-2011)“…The integrated functions of 11 Ser/Thr protein kinases (STPKs) and one phosphatase manipulate the phosphorylation levels of critical proteins in Mycobacterium…”
Get full text
Journal Article -
4
beneficial effects of feeding mahua (Bassia latifolia Roxb.) flower syrup to honey bee (Apis mellifera) colonies during periods of dearth
Published in Journal of apicultural research (2008)“…In parts of India, honey bee (Apis mellifera) colonies experience long periods of food dearth. Beekeepers traditionally feed sugar syrup during such times…”
Get full text
Journal Article -
5
The interaction of mycobacterial protein Rv2966c with host chromatin is mediated through non-CpG methylation and histone H3/H4 binding
Published in Nucleic acids research (30-04-2015)“…To effectively modulate the gene expression within an infected mammalian cell, the pathogen Mycobacterium tuberculosis would need to bring about epigenetic…”
Get full text
Journal Article -
6
Protein Kinase B (PknB) of Mycobacterium tuberculosis Is Essential for Growth of the Pathogen in Vitro as well as for Survival within the Host
Published in The Journal of biological chemistry (16-05-2014)“…The Mycobacterium tuberculosis protein kinase B (PknB) comprises an intracellular kinase domain, connected through a transmembrane domain to an extracellular…”
Get full text
Journal Article -
7
Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA
Published in Proceedings of the National Academy of Sciences - PNAS (10-10-2017)“…Mycobacterium tuberculosis’ success as a pathogen comes from its ability to evade degradation by macrophages. Normally macrophages clear microorganisms that…”
Get full text
Journal Article -
8
Protein Kinase A (PknA) of Mycobacterium tuberculosis Is Independently Activated and Is Critical for Growth in Vitro and Survival of the Pathogen in the Host
Published in The Journal of biological chemistry (10-04-2015)“…Background: Protein kinase A has been shown to be involved in modulating critical functions. Results: Although the activity of PknA is crucial for cell growth,…”
Get full text
Journal Article -
9
Deciphering soil–plant-animal continuum in relation to trace elements in middle Gangetic plain region of India
Published in Tropical animal health and production (01-07-2024)“…The soil–plant-animal continuum represents an evolving realm in biological research that’s why this study was undertaken in the middle Gangetic plain region of…”
Get full text
Journal Article -
10
Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection
Published in Scientific reports (26-04-2016)“…A mammalian cell utilizes DNA methylation to modulate gene expression in response to environmental changes during development and differentiation. Aberrant DNA…”
Get full text
Journal Article -
11
Why macrophages cannot LAP up TB
Published in Autophagy (04-03-2018)“…M. tuberculosis causes an enormous worldwide burden of disease. Its success depends upon subverting the antimicrobial capacity of macrophages. We have known…”
Get full text
Journal Article -
12
Protein kinase G confers survival advantage to Mycobacterium tuberculosis during latency-like conditions
Published in The Journal of biological chemistry (29-09-2017)“…Protein kinase G (PknG), a thioredoxin-fold–containing eukaryotic-like serine/threonine protein kinase, is a virulence factor in Mycobacterium tuberculosis,…”
Get full text
Journal Article -
13
Regulation of homocysteine metabolism by Mycobacterium tuberculosis S-adenosylhomocysteine hydrolase
Published in Scientific reports (23-07-2013)“…Mycobacterium tuberculosis modulates expression of various metabolism-related genes to adapt in the adverse host environment. The gene coding for M…”
Get full text
Journal Article -
14
Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice
Published in Nature microbiology (01-11-2024)“…Mycobacterium tuberculosis (Mtb) infects several lung macrophage populations, which have distinct abilities to restrict Mtb. What enables Mtb survival in…”
Get full text
Journal Article -
15
Period-doubling in the phase dynamics of a shunted HgTe quantum well Josephson junction
Published 12-08-2024“…The fractional AC Josephson effect is a discerning property of topological superconductivity in hybrid Josephson junctions. Recent experimental observations of…”
Get full text
Journal Article -
16