Search Results - "Uozumi, Naonori"

Effects of systemic inflammation on the network oscillation in the anterior cingulate cortex and cognitive behavior by Hirao, Ayumi, Hojo, Yasushi, Murakami, Gen, Ito, Rina, Hashizume, Miki, Murakoshi, Takayuki, Uozumi, Naonori

“…Network oscillation in the anterior cingulate cortex (ACC) plays a key role in attention, novelty detection and anxiety; however, its involvement in cognitive…”
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Biochemical properties and pathophysiological roles of cytosolic phospholipase A2s by Kita, Yoshihiro, Ohto, Takayo, Uozumi, Naonori, Shimizu, Takao

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Roles of nitric oxide as a vasodilator in neurovascular coupling of mouse somatosensory cortex by Kitaura, Hiroki, Uozumi, Naonori, Tohmi, Manavu, Yamazaki, Maya, Sakimura, Kenji, Kudoh, Masaharu, Shimizu, Takao, Shibuki, Katsuei

“…Neural activities trigger regional vasodilation in the brain. Diffusible messengers such as nitric oxide (NO) and prostanoids are considered to work as…”
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A multiplex quantitation method for eicosanoids and platelet-activating factor using column-switching reversed-phase liquid chromatography–tandem mass spectrometry by Kita, Yoshihiro, Takahashi, Toshie, Uozumi, Naonori, Shimizu, Takao

“…Eicosanoids and platelet-activating factor (PAF) are phospholipid-derived lipid mediators produced by various tissues and cells through a cascade pathway. For…”
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Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn's disease and murine colitis by Pasternak, Brad A., D'Mello, Sharon, Jurickova, Ingrid I., Han, Xiaonan, Willson, Tara, Flick, Leah, Petiniot, Lisa, Uozumi, Naonori, Divanovic, Senad, Traurnicht, Anna, Bonkowski, Erin, Kugathasan, Subra, Karp, Christopher L., Denson, Lee A.

“…Background: Systemic exposure to lipopolysaccharide (LPS) has been linked to clinical disease activity in adults with inflammatory bowel disease (IBD). We…”
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A pivotal role of cytosolic phospholipase A2 in bleomycin-induced pulmonary fibrosis by Nagase, Takahide, Uozumi, Naonori, Ishii, Satoshi, Kita, Yoshihiro, Yamamoto, Hiroshi, Ohga, Eijiro, Ouchi, Yasuyoshi, Shimizu, Takao

“…Pulmonary fibrosis is an interstitial disorder of the lung parenchyma whose mechanism is poorly understood. Potential mechanisms include the infiltration of…”
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Acute lung injury by sepsis and acid aspiration: a key role for cytosolic phospholipase A2 by Nagase, T, Uozumi, N, Ishii, S, Kume, K, Izumi, T, Ouchi, Y, Shimizu, T

“…Adult respiratory distress syndrome (ARDS) is characterized by acute lung injury with a high mortality rate and yet its mechanism is poorly understood. Sepsis…”
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Role of cytosolic phospholipase A2 in allergic response and parturition by UOZUMI, N, KUME, K, MIYAZAKI, J.-I, SHIMIZU, T, NAGASE, T, NAKATANI, N, ISHII, S, TASHIRO, F, KOMAGATA, Y, MAKI, K, IKUTA, K, OUCHI, Y

“…Phospholipase A2 (PLA2) comprises a superfamily of enzymes that hydrolyse the ester bond of phospholipids at the sn-2 position. Among the members of this…”
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Cytosolic phospholipase A2α mediates Pseudomonas aeruginosa LPS-induced airway constriction of CFTR -/- mice by Wu, Yong-Zheng, Abolhassani, Mohammad, Ollero, Mario, Dif, Fariel, Uozumi, Naonori, Lagranderie, Micheline, Shimizu, Takao, Chignard, Michel, Touqui, Lhousseine

“…BACKGROUND: Lungs of cystic fibrosis (CF) patients are chronically infected with Pseudomonas aeruginosa. Increased airway constriction has been reported in CF…”
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Roles of Cytosolic Phospholipase A2 and Platelet-Activating Factor Receptor in the Ca-Induced Biosynthesis of PAF by Shindou, Hideo, Ishii, Satoshi, Uozumi, Naonori, Shimizu, Takao

“…Casein-elicited peritoneal exudate cells (PEC), mainly consisted of neutrophils, were collected from platelet-activating factor receptor-knock-out (PAFR-KO),…”
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A potent inhibitor of cytosolic phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced lung injury in mice by Nagase, Takahide, Uozumi, Naonori, Aoki-Nagase, Tomoko, Terawaki, Kan, Ishii, Satoshi, Tomita, Tetsuji, Yamamoto, Hiroshi, Hashizume, Kohei, Ouchi, Yasuyoshi, Shimizu, Takao

“…Acute respiratory distress syndrome (ARDS) is an acute lung injury of high mortality rate, and sepsis syndrome is one of the most frequent causes of ARDS…”
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Inhibition of Cytosolic Phospholipase A2 Suppresses Production of Cholesteryl Ester through the Reesterification of Free Cholesterol but not Formation of Foam Cells in Oxidized LDL-Stimulated Macrophages by Ii, Hiromi, Oka, Mayuko, Yamashita, Atsushi, Waku, Keizo, Uozumi, Naonori, Shimizu, Takao, Sato, Takashi, Akiba, Satoshi

“…Macrophage-derived foam cells are formed as a result of the accumulation of cholesteryl ester (CE) not only in cytoplasm where CE is produced by the…”
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Platelet-activating factor mediates acid-induced lung injury in genetically engineered mice by Nagase, T, Ishii, S, Kume, K, Uozumi, N, Izumi, T, Ouchi, Y, Shimizu, T

“…Adult respiratory distress syndrome (ARDS) is an acute lung injury of high mortality rate, and the molecular mechanisms underlying it are poorly understood…”
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Pathway-oriented profiling of lipid mediators in macrophages by Kita, Yoshihiro, Takahashi, Toshie, Uozumi, Naonori, Nallan, Laxman, Gelb, Michael H., Shimizu, Takao

“…Macrophages produce various kinds of lipid mediators including eicosanoids and platelet-activating factor. Since they are produced from common precursors,…”
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B-Myb-Dependent Regulation of c-Myc Expression by Cytosolic Phospholipase A2 by Tashiro, Shigeki, Sumi, Tadateru, Uozumi, Naonori, Shimizu, Takao, Nakamura, Takashi

“…Cytosolic phospholipase A2 (cPLA2) cleaves membrane phospholipids to release arachidonic acid, initiating lipoxygenase and cyclooxygenase pathways. Mice…”
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Role of cytosolic phospholipase A2 in the production of lipid mediators and histamine release in mouse bone-marrow-derived mast cells by Nakatani, N, Uozumi, N, Kume, K, Murakami, M, Kudo, I, Shimizu, T

“…Cytosolic phospholipase A(2) (cPLA(2)) plays a critical role in mast-cell-related allergic responses [Uozumi, Kume, Nagase, Nakatani, Ishii, Tashiro, Komagata,…”
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Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoid production without activation of cytosolic phospholipase A2 alpha by Saiga, Akihiko, Uozumi, Naonori, Ono, Takashi, Seno, Kaoru, Ishimoto, Yoshikazu, Arita, Hitoshi, Shimizu, Takao, Hanasaki, Kohji

“…Group X secretory phospholipase A2 (sPLA2-X) and cytosolic phospholipase A2 alpha (cPLA2alpha) are involved in the release of arachidonic acid (AA) from…”
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Short report: Lethal malaria in cytosolic phospholipase A2- and phospholipase A2IIA-deficient mice by Ishikawa, Shumpei, Uozumi, Naonori, Shiibashi, Takashi, Izumi, Takashi, Fukayama, Masashi, Shimizu, Takao, Watanabe, Junichi, Nogami, Sadao

“…Lipid mediators play important roles in the pathogenesis of malaria. Phospholipase A2s are enzymes involved in the production of these mediators, and they…”
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Human Group IVC Phospholipase A2(cPLA2γ) by Asai, Kenji, Hirabayashi, Tetsuya, Houjou, Toshiaki, Uozumi, Naonori, Taguchi, Ryo, Shimizu, Takao

“…To create the unique properties of a certain cellular membrane, both the composition and the metabolism of membrane phospholipids are key factors…”
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cDNA Cloning, Expression, and Mutagenesis Study of Leukotriene B4 12-Hydroxydehydrogenase () by Yokomizo, Takehiko, Ogawa, Yoko, Uozumi, Naonori, Kume, Kazuhiko, Izumi, Takashi, Shimizu, Takao

“…Leukotriene B4 12-hydroxydehydrogenase catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is…”
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