Search Results - "Unterman, Irene"

Author Correction: CelFiE-ISH: a probabilistic model for multi-cell type deconvolution from single-molecule DNA methylation haplotypes by Unterman, Irene, Avrahami, Dana, Katsman, Efrat, Triche, Jr, Timothy J, Glaser, Benjamin, Berman, Benjamin P

Get full text

CelFiE-ISH: a probabilistic model for multi-cell type deconvolution from single-molecule DNA methylation haplotypes by Unterman, Irene, Avrahami, Dana, Katsman, Efrat, Tim, Jr, Triche, Glaser, Benjamin, Berman, Benjamin P

“…Deconvolution methods infer quantitative cell type estimates from bulk measurement of mixed samples including blood and tissue. DNA methylation sequencing…”
Get full text

Expanding the MECP2 network using comparative genomics reveals potential therapeutic targets for Rett syndrome by Unterman, Irene, Bloch, Idit, Cazacu, Simona, Kazimirsky, Gila, Ben-Zeev, Bruria, Berman, Benjamin P, Brodie, Chaya, Tabach, Yuval

“…Inactivating mutations in the Methyl-CpG Binding Protein 2 (MECP2) gene are the main cause of Rett syndrome (RTT). Despite extensive research into MECP2…”
Get full text

ACE2 Co-evolutionary Pattern Suggests Targets for Pharmaceutical Intervention in the COVID-19 Pandemic by Braun, Maya, Sharon, Elad, Unterman, Irene, Miller, Maya, Shtern, Anna Mellul, Benenson, Shmuel, Vainstein, Alexander, Tabach, Yuval

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spillover infection in December 2019 has caused an unprecedented pandemic. SARS-CoV-2, as…”
Get full text

Titanium Tackles the Endoplasmic Reticulum: A First Genomic Study on a Titanium Anticancer Metallodrug by Miller, Maya, Mellul, Anna, Braun, Maya, Sherill-Rofe, Dana, Cohen, Emiliano, Shpilt, Zohar, Unterman, Irene, Braitbard, Ori, Hochman, Jacob, Tshuva, Edit Y., Tabach, Yuval

“…PhenolaTi is an advanced non-toxic anticancer chemotherapy; this inert bis(phenolato)bis(alkoxo) Ti(IV) complex demonstrates the intriguing combination of high…”
Get full text

Optimization of co-evolution analysis through phylogenetic profiling reveals pathway-specific signals by Bloch, Idit, Sherill-Rofe, Dana, Stupp, Doron, Unterman, Irene, Beer, Hodaya, Sharon, Elad, Tabach, Yuval

“…Abstract Summary The exponential growth in available genomic data is expected to reach full sequencing of a million genomes in the coming decade. Improving and…”
Get full text

Cross-species identification of cancer resistance–associated genes that may mediate human cancer risk by Nair, Nishanth Ulhas, Cheng, Kuoyuan, Naddaf, Lamis, Sharon, Elad, Pal, Lipika R., Rajagopal, Padma S., Unterman, Irene, Aldape, Kenneth, Hannenhalli, Sridhar, Day, Chi-Ping, Tabach, Yuval, Ruppin, Eytan

“…Cancer is a predominant disease across animals. We applied a comparative genomics approach to systematically characterize genes whose conservation levels…”
Get full text

Multi-omics data integration analysis identifies the spliceosome as a key regulator of DNA double-strand break repair by Sherill-Rofe, Dana, Raban, Oded, Findlay, Steven, Rahat, Dolev, Unterman, Irene, Samiei, Arash, Yasmeen, Amber, Kaiser, Zafir, Kuasne, Hellen, Park, Morag, Foulkes, William D, Bloch, Idit, Zick, Aviad, Gotlieb, Walter H, Tabach, Yuval, Orthwein, Alexandre

“…DNA repair by homologous recombination (HR) is critical for the maintenance of genome stability. Germline and somatic mutations in HR genes have been…”
Get full text