Search Results - "Unterholzner, Jakob"

Serotonergic modulation of effective connectivity in an associative relearning network during task and rest by Reed, Murray Bruce, Klöbl, Manfred, Godbersen, Godber Mathis, Handschuh, Patricia Anna, Ritter, Vera, Spurny-Dworak, Benjamin, Unterholzner, Jakob, Kraus, Christoph, Gryglewski, Gregor, Winkler, Dietmar, Seiger, René, Vanicek, Thomas, Hahn, Andreas, Lanzenberger, Rupert

“…An essential core function of one's cognitive flexibility is the use of acquired knowledge and skills to adapt to ongoing environmental changes. Animal models…”
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Which component of TMS-induced electric field contributes to the antidepressant effects? by Zhang, Bella B.B., Stöhrmann, Peter, Godbersen, Godber, Unterholzner, Jakob, Kasper, Siegfried, Kranz, Georg, Lanzenberger, Rupert

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Comparison and Reliability of Hippocampal Subfield Segmentations Within FreeSurfer Utilizing T1- and T2-Weighted Multispectral MRI Data by Seiger, René, Hammerle, Fabian P., Godbersen, Godber M., Reed, Murray B., Spurny-Dworak, Benjamin, Handschuh, Patricia, Klöbl, Manfred, Unterholzner, Jakob, Gryglewski, Gregor, Vanicek, Thomas, Lanzenberger, Rupert

“…The accurate segmentation of in vivo magnetic resonance imaging (MRI) data is a crucial prerequisite for the reliable assessment of disease progression,…”
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Normal component of TMS-induced electric field is correlated with depressive symptom relief in treatment-resistant depression by Zhang, Bella B.B., Stöhrmann, Peter, Godbersen, Godber M., Unterholzner, Jakob, Kasper, Siegfried, Kranz, Georg S., Lanzenberger, Rupert

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Effects of lockdowns on neurobiological and psychometric parameters in unipolar depression during the COVID-19 pandemic by Unterholzner, Jakob, Kautzky, Alexander, Reed, Murray Bruce, Wechsler, Theresa Friederike, Popper, Valentin, Spurny-Dworak, Benjamin, Stöhrmann, Peter, Klöbl, Manfred, Varghese, Nimmy, Mühlberger, Andreas, Eckert, Anne, Frey, Richard, Rujescu, Dan, Lanzenberger, Rupert, Vanicek, Thomas

“…Defying the COVID-19 pandemic required restriction measures of unprecedented scale, that may induce and exacerbate psychiatric symptoms across the population…”
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The Impact of Theta-Burst Stimulation on Cortical GABA and Glutamate in Treatment-Resistant Depression: A Surface-Based MRSI Analysis Approach by Spurny-Dworak, Benjamin, Godbersen, Godber Mathis, Reed, Murray Bruce, Unterholzner, Jakob, Vanicek, Thomas, Baldinger-Melich, Pia, Hahn, Andreas, Kranz, Georg S., Bogner, Wolfgang, Lanzenberger, Rupert, Kasper, Siegfried

“…Background : Theta burst stimulation (TBS) belongs to one of the biological antidepressant treatment options. When applied bilaterally, excitatory intermittent…”
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Effects of bilateral sequential theta-burst stimulation on 5-HT1A receptors in the dorsolateral prefrontal cortex in treatment-resistant depression: a proof-of-concept trial by Murgaš, Matej, Unterholzner, Jakob, Stöhrmann, Peter, Philippe, Cécile, Godbersen, Godber M., Nics, Lukas, Reed, Murray B., Vraka, Chrysoula, Vanicek, Thomas, Wadsak, Wolfgang, Kranz, Georg S., Hahn, Andreas, Mitterhauser, Markus, Hacker, Marcus, Kasper, Siegfried, Lanzenberger, Rupert, Baldinger-Melich, Pia

“…Theta-burst stimulation (TBS) represents a brain stimulation technique effective for treatment-resistant depression (TRD) as underlined by meta-analyses. While…”
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Predicting Antidepressant Citalopram Treatment Response via Changes in Brain Functional Connectivity After Acute Intravenous Challenge by Klöbl, Manfred, Gryglewski, Gregor, Rischka, Lucas, Godbersen, Godber Mathis, Unterholzner, Jakob, Reed, Murray Bruce, Michenthaler, Paul, Vanicek, Thomas, Winkler-Pjrek, Edda, Hahn, Andreas, Kasper, Siegfried, Lanzenberger, Rupert

“…The early and therapy-specific prediction of treatment success in major depressive disorder is of paramount importance due to high lifetime prevalence, and…”
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Biodistribution and dosimetry of the GluN2B-specific NMDA receptor PET radioligand (R)-[11C]Me-NB1 by Rischka, Lucas, Murgaš, Matej, Pichler, Verena, Vraka, Chrysoula, Rausch, Ivo, Winkler, Dietmar, Nics, Lukas, Rasul, Sazan, Silberbauer, Leo Robert, Reed, Murray Bruce, Godbersen, Godber Mathis, Unterholzner, Jakob, Handschuh, Patricia, Gryglewski, Gregor, Mindt, Thomas, Mitterhauser, Markus, Hahn, Andreas, Ametamey, Simon Mensah, Wadsak, Wolfgang, Lanzenberger, Rupert, Hacker, Marcus

“…Background The NMDA receptor (NMDAR) plays a key role in the central nervous system, e.g., for synaptic transmission. While synaptic NMDARs are thought to have…”
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Increased left dorsolateral prefrontal cortex density following escitalopram intake during relearning: a randomized, placebo-controlled trial in healthy humans by Vanicek, Thomas, Reed, Murray B., Seiger, René, Godbersen, Godber M., Klöbl, Manfred, Unterholzner, Jakob, Spurny-Dworak, Benjamin, Gryglewski, Gregor, Handschuh, Patricia, Schmidt, Clemens, Kraus, Christoph, Stimpfl, Thomas, Rupprecht, Rainer, Kasper, Siegfried, Lanzenberger, Rupert

“…Background: Serotonergic agents affect brain plasticity and reverse stress-induced dendritic atrophy in key fronto-limbic brain areas associated with learning…”
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Corrigendum to “The effect of electroconvulsive therapy on cerebral monoamine oxidase a expression in treatment-resistant depression investigated using positron emission tomography” [Brain Stimul 12 (3) (2019) 714–723] by Baldinger-Melich, Pia, Gryglewski, Gregor, Philippe, Cécile, Murgaš, Matej, James, Gregory M., Vraka, Chrysoula, Silberbauer, Leo, Balber, Theresa, Vanicek, Thomas, Pichler, Verena, Unterholzner, Jakob, Kranz, Georg S., Hahn, Andreas, Winkler, Dietmar, Mitterhauser, Markus, Wadsak, Wolfgang, Hacker, Marcus, Kasper, Siegfried, Frey, Richard, Lanzenberger, Rupert

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How to prevent and manage hyperammonemic encephalopathies in valproate therapy by Mitschek, Marleen M M, Vanicek, Thomas, Unterholzner, Jakob, Kraus, Christoph, Weidenauer, Ana, Naderi-Heiden, Angela, Frey, Richard, Silberbauer, Leo R, Gryglewski, Gregor, Papageorgiou, Konstantinos, Winkler, Dietmar, Dold, Markus, Kasper, Siegfried, Praschak-Rieder, Nicole, Bartova, Lucie

“…•Valproic acid (VPA) can elevate plasma ammonia levels increasing the risk of encephalopathy.•Several other drugs can cause hyperammonemia that might be…”
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Spatial analysis and high resolution mapping of the human whole-brain transcriptome for integrative analysis in neuroimaging by Gryglewski, Gregor, Seiger, René, James, Gregory Miles, Godbersen, Godber Mathis, Komorowski, Arkadiusz, Unterholzner, Jakob, Michenthaler, Paul, Hahn, Andreas, Wadsak, Wolfgang, Mitterhauser, Markus, Kasper, Siegfried, Lanzenberger, Rupert

“…The quantification of big pools of diverse molecules provides important insights on brain function, but is often restricted to a limited number of…”
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Intravenous esketamine leads to an increase in impulsive and suicidal behaviour in a patient with recurrent major depression and borderline personality disorder by Vanicek, Thomas, Unterholzner, Jakob, Lanzenberger, Rupert, Naderi-Heiden, Angela, Kasper, Siegfried, Praschak-Rieder, Nicole

“…As clinical studies demonstrated that ketamine possesses rapid-acting antidepressant and antisuicidal effects, it is increasingly used in affective disorders…”
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Effects of bilateral sequential theta-burst stimulation on functional connectivity in treatment-resistant depression: First results by Stöhrmann, Peter, Godbersen, Godber Mathis, Reed, Murray Bruce, Unterholzner, Jakob, Klöbl, Manfred, Baldinger-Melich, Pia, Vanicek, Thomas, Hahn, Andreas, Lanzenberger, Rupert, Kasper, Siegfried, Kranz, Georg S.

“…Previous studies suggest that transcranial magnetic stimulation exerts antidepressant effects by altering functional connectivity (FC). However, knowledge…”
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Making Sense of Patient-Derived iPSCs, Transdifferentiated Neurons, Olfactory Neuronal Cells, and Cerebral Organoids as Models for Psychiatric Disorders by Unterholzner, Jakob, Millischer, Vincent, Wotawa, Christoph, Sawa, Akira, Lanzenberger, Rupert

“…Abstract The improvement of experimental models for disorders requires a constant approximation towards the dysregulated tissue. In psychiatry, where an…”
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Changes in White Matter Microstructure After Electroconvulsive Therapy for Treatment-Resistant Depression by Gryglewski, Gregor, Seiger, René, Baldinger-Melich, Pia, Unterholzner, Jakob, Spurny, Benjamin, Vanicek, Thomas, Hahn, Andreas, Kasper, Siegfried, Frey, Richard, Lanzenberger, Rupert

“…Abstract Background Treatment-resistant depression is among the most debilitating conditions in psychiatry. Recent studies have associated alterations in white…”
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Topologically Guided Prioritization of Candidate Gene Transcripts Coexpressed with the 5-HT1A Receptor by Combining In Vivo PET and Allen Human Brain Atlas Data by Unterholzner, Jakob, Gryglewski, Gregor, Philippe, Cecile, Seiger, Rene, Pichler, Verena, Godbersen, Godber M, Berroterán-Infante, Neydher, Murgaš, Matej, Hahn, Andreas, Wadsak, Wolfgang, Mitterhauser, Markus, Kasper, Siegfried, Lanzenberger, Rupert

“…Abstract The serotonin-1A receptor (5-HT1AR) represents a viable target in the treatment of disorders of the brain. However, development of psychiatric drugs…”
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ABCB1 variants and sex affect serotonin transporter occupancy in the brain by Silberbauer, Leo R., Rischka, Lucas, Vraka, Chrysoula, Hartmann, Annette M., Godbersen, Godber Mathis, Philippe, Cécile, Pacher, Daniel, Nics, Lukas, Klöbl, Manfred, Unterholzner, Jakob, Stimpfl, Thomas, Wadsak, Wolfgang, Hahn, Andreas, Hacker, Marcus, Rujescu, Dan, Kasper, Siegfried, Lanzenberger, Rupert, Gryglewski, Gregor

“…Strategies to personalize psychopharmacological treatment promise to improve efficacy and tolerability. We measured serotonin transporter occupancy immediately…”
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First-in-Humans Brain PET Imaging of the GluN2B-Containing N-methyl-d-aspartate Receptor with (R)-11C-Me-NB1 by Rischka, Lucas, Vraka, Chrysoula, Pichler, Verena, Rasul, Sazan, Nics, Lukas, Gryglewski, Gregor, Handschuh, Patricia, Murgaš, Matej, Godbersen, Godber M, Silberbauer, Leo R, Unterholzner, Jakob, Wotawa, Christoph, Haider, Ahmed, Ahmed, Hazem, Schibli, Roger, Mindt, Thomas, Mitterhauser, Markus, Wadsak, Wolfgang, Hahn, Andreas, Lanzenberger, Rupert, Hacker, Marcus, Ametamey, Simon M

“…The N-methyl-d-aspartate receptor (NMDAR) plays a crucial role in neurodegenerative diseases such as Alzheimer disease and in the treatment of major depression…”
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