Search Results - "Untereiner, Ashley"

Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells by Untereiner, Ashley A., Pavlidou, Athanasia, Druzhyna, Nadiya, Papapetropoulos, Andreas, Hellmich, Mark R., Szabo, Csaba

“…[Display omitted] Hydrogen sulfide (H2S) production in colon cancer cells supports cellular bioenergetics and proliferation. The aim of the present study was…”
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S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics by Módis, Katalin, Ju, YoungJun, Ahmad, Akbar, Untereiner, Ashley A., Altaany, Zaid, Wu, Lingyun, Szabo, Csaba, Wang, Rui

“…[Display omitted] Mammalian cells can utilize hydrogen sulfide (H2S) to support mitochondrial respiration. The aim of our study was to explore the potential…”
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H2S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells by Untereiner, Ashley A., Oláh, Gabor, Módis, Katalin, Hellmich, Mark R., Szabo, Csaba

“…[Display omitted] Cystathionine-β-synthase (CBS) is upregulated and hydrogen sulfide (H2S) production is increased in colon cancer cells. The functional…”
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Decreased Gluconeogenesis in the Absence of Cystathionine Gamma-Lyase and the Underlying Mechanisms by Untereiner, Ashley A, Wang, Rui, Ju, YoungJun, Wu, Lingyun

“…To investigate the regulation of hepatic glucose production by cystathionine γ-lyase (CSE)-generated hydrogen sulfide (H2S) in hepatic glucose production under…”
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Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis by Mani, Sarathi, Li, Hongzhu, Untereiner, Ashley, Wu, Lingyun, Yang, Guangdong, Austin, Richard C, Dickhout, Jeffrey G, Lhoták, Šárka, Meng, Qing H, Wang, Rui

“…BACKGROUND—Cystathionine γ-lyase (CSE) produces hydrogen sulfide (H2S) in the cardiovascular system. The deficiency of CSE in mice leads to a decreased…”
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Stimulatory effect of CSE-generated H2S on hepatic mitochondrial biogenesis and the underlying mechanisms by Untereiner, Ashley A., Fu, Ming, Módis, Katalin, Wang, Rui, Ju, YoungJun, Wu, Lingyun

“…We previously showed that hydrogen sulfide (H2S) upregulates peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α in primary hepatocytes. PGC-1α…”
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Increased renal methylglyoxal formation with down-regulation of PGC-1α-FBPase pathway in cystathionine γ-lyase knockout mice by Untereiner, Ashley A, Dhar, Arti, Liu, Jianghai, Wu, Lingyun

“…We have previously reported that hydrogen sulfide (H(2)S), a gasotransmitter and vasodilator has cytoprotective properties against methylglyoxal (MG), a…”
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H 2 S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells by Untereiner, Ashley A, Oláh, Gabor, Módis, Katalin, Hellmich, Mark R, Szabo, Csaba

“…Cystathionine-β-synthase (CBS) is upregulated and hydrogen sulfide (H S) production is increased in colon cancer cells. The functional consequence of this…”
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Interaction of methylglyoxal and hydrogen sulfide in rat vascular smooth muscle cells by Chang, Tuanjie, Untereiner, Ashley, Liu, Jianghai, Wu, Lingyun

“…Hydrogen sulfide (H(2)S) is a gasotransmitter with multifaceted physiological functions, including the regulation of glucose metabolism. Methylglyoxal (MG) is…”
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Cystathionine-beta-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach by Chao, Celia, Zatarain, John R, Ding, Ye, Coletta, Ciro, Mrazek, Amy A, Druzhyna, Nadiya, Johnson, Paul, Chen, Haiying, Hellmich, Judy L, Asimakopoulou, Antonia, Yanagi, Kazunori, Olah, Gabor, Szoleczky, Petra, Törö, Gabor, Bohanon, Fredrick J, Cheema, Minal, Lewis, Rachel, Eckelbarger, David, Ahmad, Akbar, Módis, Katalin, Untereiner, Ashley, Szczesny, Bartosz, Papapetropoulos, Andreas, Zhou, Jia, Hellmich, Mark R, Szabo, Csaba

“…Colon cancer cells contain high levels of cystathionine-beta-synthase (CBS). Its product, hydrogen sulfide (H S) promotes the growth and proliferation of…”
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Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept by Hellmich, Mark R., Chao, Celia, Módis, Katalin, Ding, Ye, Zatarain, John R., Thanki, Ketan, Maskey, Manjit, Druzhyna, Nadiya, Untereiner, Ashley A., Ahmad, Akbar, Xue, Yu, Chen, Haiying, Russell, William K., Wang, Jianmei, Zhou, Jia, Szabo, Csaba

“…Upregulation of hydrogen sulfide (H2S) biosynthesis, at least in part related to the upregulation of cystathionine β-synthetase (CBS) in cancer cells, serves…”
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Hydrogen Sulfide and Glucose Homeostasis: A Tale of Sweet and the Stink by Untereiner, Ashley, Wu, Lingyun

“…Among many endogenous mediators, the gasotransmitter hydrogen sulfide (H S) plays an important role in the regulation of glucose homeostasis. In this article…”
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Hydrogen sulfide and the pathogenesis of atherosclerosis by Mani, Sarathi, Untereiner, Ashley, Wu, Lingyun, Wang, Rui

“…Stigmatized as a toxic environmental pollutant for centuries, hydrogen sulfide (H2S) has gained recognition over the last decade as an important…”
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H2S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells by Ju, YoungJun, Untereiner, Ashley, Wu, Lingyun, Yang, Guangdong

“…Cystathionine gamma-lyase (CSE)-derived hydrogen sulfide (H2S) possesses diverse roles in the liver, affecting lipoprotein synthesis, insulin sensitivity, and…”
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GABA promotes β‐cell proliferation, but does not overcome impaired glucose homeostasis associated with diet‐induced obesity by Untereiner, Ashley, Abdo, Shaaban, Bhattacharjee, Alpana, Gohil, Himaben, Pourasgari, Farzaneh, Ibeh, Neke, Lai, Mi, Batchuluun, Battsetseg, Wong, Anthony, Khuu, Nicholas, Liu, Ying, Rijjal, Dana Al, Winegarden, Neil, Virtanen, Carl, Orser, Beverley A., Cabrera, Over, Varga, Gabor, Rocheleau, Jonathan, Dai, Feihan F., Wheeler, Michael B.

“…ABSTRACT γ‐Aminobutyric acid (GABA) administration has been shown to increase β‐cell mass, leading to a reversal of type 1 diabetes in mice. Whether GABA has…”
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γ‐aminobutyric acid stimulates β‐cell proliferation through the mTORC1/p70S6K pathway, an effect amplified by Ly49, a novel γ‐aminobutyric acid type A receptor positive allosteric modulator by Untereiner, Ashley, Xu, Jie, Bhattacharjee, Alpana, Cabrera, Over, Hu, Cheng, Dai, Feihan F., Wheeler, Michael B.

“…Aim To examine the mechanism of action of γ‐aminobutyric acid (GABA) on β‐cell proliferation and investigate if co‐treatment with Ly49, a novel GABA type A…”
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Hydrogen Sulfide Impairs Glucose Utilization and Increases Gluconeogenesis in Hepatocytes by Zhang, Ling, Yang, Guangdong, Untereiner, Ashley, Ju, Youngjun, Wu, Lingyun, Wang, Rui

“…Mounting evidence has established hydrogen sulfide (H2S) as an important gasotransmitter with multifaceted physiological functions. The aim of the present…”
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PP33 - H2S-induced increase in hepatic glucose production and the underlying mechanisms by Untereiner, Ashley Anne, Wang, Rui, Wu, Lingyun

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H2S-induced increase in hepatic glucose production and the underlying mechanisms by Untereiner, Ashley Anne, Wang, Rui, Wu, Lingyun

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Oxidative stress and aging: is methylglyoxal the hidden enemy? by Desai, Kaushik M, Chang, Tuanjie, Wang, Hui, Banigesh, Ali, Dhar, Arti, Liu, Jianghai, Untereiner, Ashley, Wu, Lingyun

“…Aging is a multifactorial process that involves changes at the cellular, tissue, organ and the whole body levels resulting in decreased functioning,…”
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