Search Results - "Unsicker, K."

Extracellular signal-regulated kinase as an inducer of non-apoptotic neuronal death by Subramaniam, S., Unsicker, K.

“…Extracellular signal-regulated kinase (ERK) is a versatile protein kinase, which has been implicated in signaling numerous biological functions ranging from…”
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Age-related alterations in hippocampal spines and deficiencies in spatial memory in mice by von Bohlen und Halbach, O., Zacher, C., Gass, P., Unsicker, K.

“…Alterations in neuronal morphology occur in the brain during normal aging, but vary depending on neuronal cell types and brain regions. Such alterations have…”
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TGF-β in aging and disease by Krieglstein, K, Miyazono, K, ten Dijke, P, Unsicker, K

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Implications of p75NTR for dentate gyrus morphology and hippocampus-related behavior revisited by Dokter, M., Busch, R., Poser, R., Vogt, M. A., von Bohlen und Halbach, V., Gass, P., Unsicker, K., von Bohlen und Halbach, O.

“…The pan-neurotrophin receptor p75NTR is expressed in the adult brain in a discrete pattern. Although numerous studies have addressed its implications for…”
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Functions of Fibroblast Growth Factor (FGF)-2 and FGF-5 in Astroglial Differentiation and Blood-Brain Barrier Permeability: Evidence from Mouse Mutants by Reuss, Bernhard, Dono, Rosanna, Unsicker, Klaus

“…Multiple evidence suggests that fibroblast growth factors (FGFs), most prominently FGF-2, affect astroglial proliferation, maturation, and transition to a…”
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Antidepressant-mediated reversal of abnormal behavior and neurodegeneration in mice following olfactory bulbectomy by Jarosik, J., Legutko, B., Unsicker, K., von Bohlen und Halbach, O.

“…Olfactory bulbectomy is an established animal model of depression that has been mostly investigated in rats. As in human major depression, bulbectomy induces…”
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TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines by von Bohlen und Halbach, O, Minichiello, L, Unsicker, K

“…Abstract Dendritic spines are major sites of excitatory synaptic transmission and changes in their densities have been linked to alterations in learning and…”
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Roles of exogenous and endogenous FGF-2 in animal models of depression by Jarosik, J, Legutko, B, Werner, S, Unsicker, K, von Bohlen Und Halbach, O

“…Several members of the fibroblast growth factor (FGF) family have been shown to be dysregulated in individuals with major depression, and treatment with…”
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Cell interactions with the extracellular matrix by Bruckner-Tuderman, L., von der Mark, K., Pihlajaniemi, T., Unsicker, K.

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GDNF: a cytokine at the interface of TGF-βs and neurotrophins by Unsicker, K.

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Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation by Cole, T J, Blendy, J A, Monaghan, A P, Krieglstein, K, Schmid, W, Aguzzi, A, Fantuzzi, G, Hummler, E, Unsicker, K, Schütz, G

“…The role of the glucocorticoid receptor (GR) in glucocorticoid physiology and during development was investigated by generation of GR-deficient mice by gene…”
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TGF‐beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity by Krieglstein, K., Suter‐Crazzolara, C., Fischer, W.H., Unsicker, K.

“…The superfamily of transforming growth factors‐beta (TGF‐beta) comprises an expanding list of multifunctional proteins serving as regulators of cell…”
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Expression of a novel member of the TGF-beta superfamily, growth/differentiation factor-15/macrophage-inhibiting cytokine-1 (GDF-15/MIC-1) in adult rat tissues by Böttner, M, Suter-Crazzolara, C, Schober, A, Unsicker, K

“…We have cloned a novel member of the transforming growth factor-beta (TGF-beta) superfamily from a human placental cDNA library. The sequence is identical to…”
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Growth/Differentiation Factor-15/Macrophage Inhibitory Cytokine-1 Is a Novel Trophic Factor for Midbrain Dopaminergic Neurons In Vivo by Strelau, Jens, Sullivan, Aideen, Bottner, Martina, Lingor, Paul, Falkenstein, Elisabeth, Suter-Crazzolara, Clemens, Galter, Dagmar, Jaszai, Jozsef, Krieglstein, Kerstin, Unsicker, Klaus

“…Transforming growth factor-betas (TGF-betas) constitute an expanding family of multifunctional cytokines with prominent roles in development, cell…”
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F-spondin regulates neuronal survival through activation of disabled-1 in the chicken ciliary ganglion by Peterziel, H., Sackmann, T., Strelau, J., Kuhn, P.H., Lichtenthaler, S.F., Marom, K., Klar, A., Unsicker, K.

“…The extracellular membrane-associated protein F-spondin has been implicated in cell–matrix and cell–cell adhesion and plays an important role in axonal…”
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The chromaffin cell: paradigm in cell, developmental and growth factor biology by Unsicker, K

“…This article reviews the chromaffin cell in relation to studies that have elucidated fundamental phenomena in cell biology (the molecular anatomy of…”
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c-ret regulates cholinergic properties in mouse sympathetic neurons: evidence from mutant mice by Burau, K., Stenull, I., Huber, K., Misawa, H., Berse, B., Unsicker, K., Ernsberger, U.

“…The search for signalling systems regulating development of noradrenergic and cholinergic sympathetic neurons is a classical problem of developmental…”
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The trophic cocktail made by adrenal chromaffin cells by Unsicker, K

“…The beneficial effect of chromaffin cell grafts to the striatum in patients with Morbus Parkinson and in animal models of the disease may be due to liberated…”
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Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 by Kiprianova, Irina, Schindowski, Katharina, von Bohlen und Halbach, Oliver, Krause, Sonja, Dono, Rosanna, Schwaninger, Markus, Unsicker, Klaus

“…FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have…”
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Fibroblast growth factors-5 and -9 distinctly regulate expression and function of the gap junction protein connexin43 in cultured astroglial cells from different brain regions by Reuss, B., Hertel, M., Werner, S., Unsicker, K.

“…Astroglial cells contribute to neuronal maintenance and function in the normal and diseased brain. Gap junctions formed predominantly by connexin43 (cx43)…”
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