Search Results - "Uno, Masaharu"

Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans by Kishimoto, Saya, Uno, Masaharu, Okabe, Emiko, Nono, Masanori, Nishida, Eisuke

“…Hormesis is a biological phenomenon, whereby exposure to low levels of toxic agents or conditions increases organismal viability. It thus represents a…”
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The microRNA machinery regulates fasting-induced changes in gene expression and longevity in Caenorhabditis elegans by Kogure, Akiko, Uno, Masaharu, Ikeda, Takako, Nishida, Eisuke

“…Intermittent fasting (IF) is a dietary restriction regimen that extends the lifespans of Caenorhabditis elegans and mammals by inducing changes in gene…”
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Lactobacillus paracasei subsp. paracasei 2004 improves health and lifespan in Caenorhabditis elegans by Kishimoto, Saya, Nono, Masanori, Makizaki, Yutaka, Tanaka, Yoshiki, Ohno, Hiroshi, Nishida, Eisuke, Uno, Masaharu

“…Recent research has highlighted the importance of the gut microbiome in regulating aging, and probiotics are interventions that can promote gut health. In this…”
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Intestine-to-Germline Transmission of Epigenetic Information Intergenerationally Ensures Systemic Stress Resistance in C. elegans by Nono, Masanori, Kishimoto, Saya, Sato-Carlton, Aya, Carlton, Peter Mark, Nishida, Eisuke, Uno, Masaharu

“…Changes in epigenetic states affect organismal homeostasis, including stress resistance. However, the mechanisms coordinating epigenetic states and systemic…”
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Octopamine enhances oxidative stress resistance through the fasting‐responsive transcription factor DAF‐16/FOXO in C. elegans by Hoshikawa, Haruka, Uno, Masaharu, Honjoh, Sakiko, Nishida, Eisuke

“…Dietary restriction regimens lead to enhanced stress resistance and extended life span in many species through the regulation of fasting and/or diet‐responsive…”
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Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans by Okabe, Emiko, Uno, Masaharu, Kishimoto, Saya, Nishida, Eisuke

“…Environmental conditions can cause phenotypic changes, part of which can be inherited by subsequent generations via soma-to-germline communication. However,…”
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Molecular mechanisms regulating lifespan and environmental stress responses by Kishimoto, Saya, Uno, Masaharu, Nishida, Eisuke

“…Throughout life, organisms are subjected to a variety of environmental perturbations, including temperature, nutrient conditions, and chemical agents. Exposure…”
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A Fasting-Responsive Signaling Pathway that Extends Life Span in C. elegans by Uno, Masaharu, Honjoh, Sakiko, Matsuda, Mitsuhiro, Hoshikawa, Haruka, Kishimoto, Saya, Yamamoto, Tomohito, Ebisuya, Miki, Yamamoto, Takuya, Matsumoto, Kunihiro, Nishida, Eisuke

“…Intermittent fasting is one of the most effective dietary restriction regimens that extend life span in C. elegans and mammals. Fasting-stimulus responses are…”
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Neuronal DAF-16-to-intestinal DAF-16 communication underlies organismal lifespan extension in C. elegans by Uno, Masaharu, Tani, Yuri, Nono, Masanori, Okabe, Emiko, Kishimoto, Saya, Takahashi, Chika, Abe, Ryoji, Kurihara, Takuya, Nishida, Eisuke

“…Previous studies have revealed the importance of inter-tissue communications for lifespan regulation. However, the inter-tissue network responsible for…”
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Effect of the boron content on the steam activation of boron-doped diamond electrodes by Zhang, Junfeng, Nakai, Takaaki, Uno, Masaharu, Nishiki, Yoshinori, Sugimoto, Wataru

“…In order to investigate the initial stages of the steam-activation process of boron-doped diamond (BDD) electrodes, polycrystalline BDD electrodes with…”
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Lifespan-regulating genes in C. elegans by Uno, Masaharu, Nishida, Eisuke

“…The molecular mechanisms underlying the aging process have garnered much attention in recent decades because aging is the most significant risk factor for many…”
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Evaluation of Ag-based gas-diffusion electrode for two-compartment cell used in novel chlor-alkali membrane process by Sudoh, Masao, Arai, Kenji, Izawa, Yuki, Suzuki, Tomohisa, Uno, Masaharu, Tanaka, Masashi, Hirao, Kazuhiro, Nishiki, Yoshinori

“…The oxygen-depolarized cathode has become attractive by reducing energy consumption and also CO 2 emissions. The initial gas-diffusion electrode was for a…”
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Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases by Nakamura, Hiroyuki, Sasaki, Yusuke, Uno, Masaharu, Yoshikawa, Tomohiro, Asano, Toru, Ban, Hyun Seung, Fukazawa, Hidesuke, Shibuya, Masabumi, Uehara, Yoshimasa

“…A series of benzamidines and benzamides was synthesized as selective inhibitors of vascular endothelial growth factor receptor (VEGFR) tyrosine kinases, and…”
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Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans by Nishida, Eisuke, Yamamoto, Takuya, Honjoh, Sakiko, Uno, Masaharu

“…Dietary restriction is the most effective and reproducible intervention to extend lifespan in divergent species. In mammals, two regimens of dietary…”
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The MYST family histone acetyltransferase complex regulates stress resistance and longevity through transcriptional control of DAF‐16/FOXO transcription factors by Ikeda, Takako, Uno, Masaharu, Honjoh, Sakiko, Nishida, Eisuke

“…The well‐known link between longevity and the Sir2 histone deacetylase family suggests that histone deacetylation, a modification associated with repressed…”
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Src family kinases suppress differentiation of brown adipocytes and browning of white adipocytes by Usui, Mai, Uno, Masaharu, Nishida, Eisuke

“…Brown adipocytes and beige adipocytes can expend energy, generate heat, and increase whole‐body energy expenditure. The detailed mechanisms of adipogenesis and…”
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Cholesterol regulates DAF-16 nuclear localization and fasting-induced longevity in C. elegans by Ihara, Akiko, Uno, Masaharu, Miyatake, Koichi, Honjoh, Sakiko, Nishida, Eisuke

“…Cholesterol has attracted significant attention as a possible lifespan regulator. It has been reported that serum cholesterol levels have an impact on…”
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Single housing of juveniles accelerates early-stage growth but extends adult lifespan in African turquoise killifish by Takahashi, Chika, Okabe, Emiko, Nono, Masanori, Kishimoto, Saya, Matsui, Hideaki, Ishitani, Tohru, Yamamoto, Takuya, Uno, Masaharu, Nishida, Eisuke

“…Within the same species, individuals exhibiting faster growth tend to have shorter lifespans, even if their fast growth arises from early-life pharmacological…”
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Preferential {100} etching of boron-doped diamond electrodes and diamond particles by CO2 activation by Zhang, Junfeng, Nakai, Takaaki, Uno, Masaharu, Nishiki, Yoshinori, Sugimoto, Wataru

“…The etching behavior of polycrystalline boron-doped diamond (BDD) electrodes and diamond particles with gaseous CO2 at 800 and 900°C was investigated by…”
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Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitors by Uno, Masaharu, Koma, Yosuke, Ban, Hyun Seung, Nakamura, Hiroyuki

“…Compound 4 (GN6958) was found to be a potent inhibitor against SUMO-Sentrin Specific Protease (SENP)1 without inhibiting other protease enzyme activities in…”
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