Search Results - "Uno, Kazuko"

Peripheral helper-T-cell-derived CXCL13 is a crucial pathogenic factor in idiopathic multicentric Castleman disease by Harada, Takuya, Kikushige, Yoshikane, Miyamoto, Toshihiro, Uno, Kazuko, Niiro, Hiroaki, Kawakami, Atsushi, Koga, Tomohiro, Akashi, Koichi, Yoshizaki, Kazuyuki

“…Castleman disease (CD) is a rare lymphoproliferative disorder. Among subtypes of CD, idiopathic multicentric CD-not otherwise specified (iMCD-NOS) has a poor…”
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Anti-nucleocapsid antibodies enhance the production of IL-6 induced by SARS-CoV-2 N protein by Nakayama, Emi E., Kubota-Koketsu, Ritsuko, Sasaki, Tadahiro, Suzuki, Keita, Uno, Kazuko, Shimizu, Jun, Okamoto, Toru, Matsumoto, Hisatake, Matsuura, Hiroshi, Hashimoto, Shoji, Tanaka, Toshio, Harada, Hiromasa, Tomita, Masafumi, Kaneko, Mitsunori, Yoshizaki, Kazuyuki, Shioda, Tatsuo

“…A cytokine storm induces acute respiratory distress syndrome, the main cause of death in coronavirus disease 2019 (COVID-19) patients. However, the detailed…”
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The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction by Luqman-Fatah, Ahmad, Watanabe, Yuzo, Uno, Kazuko, Ishikawa, Fuyuki, Moran, John V., Miyoshi, Tomoichiro

“…Some interferon stimulated genes (ISGs) encode proteins that inhibit LINE-1 (L1) retrotransposition. Here, we use immunoprecipitation followed by liquid…”
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Author Correction: The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction by Luqman-Fatah, Ahmad, Watanabe, Yuzo, Uno, Kazuko, Ishikawa, Fuyuki, Moran, John V., Miyoshi, Tomoichiro

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Twitter use in scientific communication revealed by visualization of information spreading by influencers within half a year after the Fukushima Daiichi nuclear power plant accident by Tsubokura, Masaharu, Onoue, Yosuke, Torii, Hiroyuki A, Suda, Saori, Mori, Kohei, Nishikawa, Yoshitaka, Ozaki, Akihiko, Uno, Kazuko

“…Scientific communication through social media, particularly Twitter has been gaining importance in recent years. As such, it is critical to understand how…”
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Predictive biomarkers of COVID-19 prognosis identified in Bangladesh patients and validated in Japanese cohorts by Uno, Kazuko, Hasan, Abu, Nakayama, Emi E., Rahim, Rummana, Harada, Hiromasa, Kaneko, Mitsunori, Hashimoto, Shoji, Tanaka, Toshio, Matsumoto, Hisatake, Fujimiya, Hitoshi, Shioda, Tatsuo, Rahman, Mizanur, Yoshizaki, Kazuyuki

“…Despite high vaccination rates globally, countries are still grappling with new COVID infections, and patients diagnosed as mild dying at home during…”
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Enhancement of IL-6 Production Induced by SARS-CoV-2 Nucleocapsid Protein and Bangladeshi COVID-19 Patients’ Sera by Hasan, Abu, Rahim, Rummana, Nakayama, Emi E, Uno, Kazuko, Hasan, Nazmul, Rahman, Mizanur, Shioda, Tatsuo

“…Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by severe acute respiratory syndrome coronavirus 2 that can have detrimental…”
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Pretreatment Prediction of Individual Rheumatoid Arthritis Patients' Response to Anti-Cytokine Therapy Using Serum Cytokine/Chemokine/Soluble Receptor Biomarkers by Uno, Kazuko, Yoshizaki, Kazuyuki, Iwahashi, Mitsuhiro, Yamana, Jiro, Yamana, Seizo, Tanigawa, Miki, Yagi, Katsumi

“…The inability to match rheumatoid arthritis (RA) patients with the anti-cytokine agent most efficacious for them is a major hindrance to patients’ speedy…”
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Cryptococcus neoformans Infection in Mice Lacking Type I Interferon Signaling Leads to Increased Fungal Clearance and IL-4-Dependent Mucin Production in the Lungs by Sato, Ko, Yamamoto, Hideki, Nomura, Toshiki, Matsumoto, Ikumi, Miyasaka, Tomomitsu, Zong, Tong, Kanno, Emi, Uno, Kazuko, Ishii, Keiko, Kawakami, Kazuyoshi

“…Type I interferons (IFNs) are secreted by many cell types upon stimulation via pattern recognition receptors and bind to IFN-α/β receptor (IFNAR), which is…”
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Simulation of Information Spreading on Twitter Concerning Radiation After the Fukushima Nuclear Power Plant Accident by Sano, Yukie, Torii, Hiroyuki A., Onoue, Yosuke, Uno, Kazuko

“…Information spreading on social media is a crucial issue to build a safe society. In particular, during emergencies, misinformation and uncertain information…”
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Matrix metalloproteinase-10: a novel biomarker for idiopathic pulmonary fibrosis by Sokai, Akihiko, Handa, Tomohiro, Tanizawa, Kiminobu, Oga, Toru, Uno, Kazuko, Tsuruyama, Tatsuaki, Kubo, Takeshi, Ikezoe, Kohei, Nakatsuka, Yoshinari, Tanimura, Kazuya, Muro, Shigeo, Hirai, Toyohiro, Nagai, Sonoko, Chin, Kazuo, Mishima, Michiaki

“…Matrix metalloproteinases (MMPs) are believed to be involved in the pathogenesis of idiopathic pulmonary fibrosis (IPF), and MMP-7 has been described as a…”
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Tentative diagnostic criteria and disease severity classification for Castleman disease: A report of the research group on Castleman disease in Japan by Fujimoto, Shino, Koga, Tomohiro, Kawakami, Atsushi, Kawabata, Hiroshi, Okamoto, Shinichiro, Mizuki, Masao, Yano, Shingo, Ide, Makoto, Uno, Kazuko, Yagi, Katsumi, Kojima, Toshiyuki, Mizutani, Minoru, Tokumine, Yukihiro, Nishimoto, Norihiro, Fujiwara, Hiroshi, Nakatsuka, Shin-ichi, Shiozawa, Kazuko, Iwaki, Noriko, Masaki, Yasufumi, Yoshizaki, Kazuyuki

“…Objectives: To determine the tentative diagnostic criteria and disease severity classification for Castleman disease (CD) and describe the clinical and…”
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Cutaneous T-cell-attracting chemokine as a novel biomarker for predicting prognosis of idiopathic pulmonary fibrosis: a prospective observational study by Niwamoto, Takafumi, Handa, Tomohiro, Murase, Yuko, Nakatsuka, Yoshinari, Tanizawa, Kiminobu, Taguchi, Yoshio, Tomioka, Hiromi, Tomii, Keisuke, Kita, Hideo, Uyama, Michihiro, Tsuchiya, Michiko, Emura, Masahito, Kawamura, Tetsuji, Arai, Naoki, Arita, Machiko, Uno, Kazuko, Yoshizawa, Akihiko, Uozumi, Ryuji, Yamaguchi, Izumi, Matsuda, Fumihiko, Chin, Kazuo, Hirai, Toyohiro

“…Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrotic lung disease that leads to respiratory failure and death. Although…”
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Renal redox dysregulation in AKI: application for oxidative stress marker of AKI by Kasuno, Kenji, Shirakawa, Kiichi, Yoshida, Haruyoshi, Mori, Kiyoshi, Kimura, Hideki, Takahashi, Naoki, Nobukawa, Yasunari, Shigemi, Kenji, Tanabe, Sawaka, Yamada, Narihisa, Koshiji, Takaaki, Nogaki, Fumiaki, Kusano, Hitoshi, Ono, Takahiko, Uno, Kazuko, Nakamura, Hajime, Yodoi, Junji, Muso, Eri, Iwano, Masayuki

“…Oxidative stress is a major determinant of acute kidney injury (AKI); however, the effects of an AKI on renal redox system are unclear, and few existing AKI…”
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Analysis of systemic and airway inflammation in obstructive sleep apnea by Aihara, Kensaku, Oga, Toru, Chihara, Yuichi, Harada, Yuka, Tanizawa, Kiminobu, Handa, Tomohiro, Hitomi, Takefumi, Uno, Kazuko, Mishima, Michiaki, Chin, Kazuo

“…Purpose The presence of both systemic and airway inflammation has been suggested in obstructive sleep apnea (OSA) by increased levels of inflammatory…”
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Beneficial effects of anti-apolipoprotein A-2 on an animal model for coronary arteritis in Kawasaki disease by Ito, Fuyu, Oharaseki, Toshiaki, Tsukui, Daisuke, Kimura, Yoshitaka, Yanagida, Tamiko, Kishi, Fukuko, Yamakawa, Yoshio, Kameoka, Yosuke, Suzuki, Shoichi, Uno, Kazuko, Suzuki, Osamu, Miura, Noriko N, Ohno, Naohito, Takahashi, Kei, Kono, Hajime, Suzuki, Kazuo

“…Kawasaki disease (KD) is usually treated with high-dose intravenous immunoglobulin (IVIg) as severe infectious and other diseases. Due to issues that are…”
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Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma by Ikezoe, Kohei, Oga, Toru, Honda, Tetsuya, Hara-Chikuma, Mariko, Ma, Xiaojun, Tsuruyama, Tatsuaki, Uno, Kazuko, Fuchikami, Jun-ichi, Tanizawa, Kiminobu, Handa, Tomohiro, Taguchi, Yoshio, Verkman, Alan S., Narumiya, Shuh, Mishima, Michiaki, Chin, Kazuo

“…Oxidative stress plays a pivotal role in the pathogenesis of asthma. Aquaporin-3 (AQP3) is a small transmembrane water/glycerol channel that may facilitate the…”
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Thioredoxin-1 protects against neutrophilic inflammation and emphysema progression in a mouse model of chronic obstructive pulmonary disease exacerbation by Tanabe, Naoya, Hoshino, Yuma, Marumo, Satoshi, Kiyokawa, Hirofumi, Sato, Susumu, Kinose, Daisuke, Uno, Kazuko, Muro, Shigeo, Hirai, Toyohiro, Yodoi, Junji, Mishima, Michiaki

“…Exacerbations of chronic obstructive pulmonary disease (COPD) are characterized by acute enhancement of airway neutrophilic inflammation under oxidative stress…”
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Phase I clinical trial of fibronectin CH296-stimulated T cell therapy in patients with advanced cancer by Ishikawa, Takeshi, Kokura, Satoshi, Enoki, Tatsuji, Sakamoto, Naoyuki, Okayama, Tetsuya, Ideno, Mitsuko, Mineno, Junichi, Uno, Kazuko, Yoshida, Naohisa, Kamada, Kazuhiro, Katada, Kazuhiro, Uchiyama, Kazuhiko, Handa, Osamu, Takagi, Tomohisa, Konishi, Hideyuki, Yagi, Nobuaki, Naito, Yuji, Itoh, Yoshito, Yoshikawa, Toshikazu

“…Previous studies have demonstrated that less-differentiated T cells are ideal for adoptive T cell transfer therapy (ACT) and that fibronectin CH296 (FN-CH296)…”
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Prompt Reduction in CRP, IL-6, IFN-γ, IP-10, and MCP-1 and a Relatively Low Basal Ratio of Ferritin/CRP Is Possibly Associated With the Efficacy of Tocilizumab Monotherapy in Severely to Critically Ill Patients With COVID-19 by Hashimoto, Shoji, Yoshizaki, Kazuyuki, Uno, Kazuko, Kitajima, Heita, Arai, Tsuyoshi, Tamura, Yoshitaka, Morishita, Hiroshi, Matsuoka, Hiroto, Han, Yuki, Minamoto, Seijiro, Hirashima, Tomonori, Yamada, Tomoki, Kashiwa, Yozo, Kameda, Makoto, Yamaguchi, Seiji, Tsuchihashi, Yasunari, Iwahashi, Mitsuhiro, Nakayama, Emi, Shioda, Tatsuo, Nagai, Takayuki, Tanaka, Toshio

“…Tocilizumab, a humanized anti-IL-6 receptor antibody, has been used to treat severely to critically ill patients with COVID-19. A living systematic review with…”
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