Search Results - "Unnikrishnan, Ginu"

A 3-D virtual human thermoregulatory model to predict whole-body and organ-specific heat-stress responses by Unnikrishnan, Ginu, Hatwar, Rajeev, Hornby, Samantha, Laxminarayan, Srinivas, Gulati, Tushar, Belval, Luke N., Giersch, Gabrielle E. W., Kazman, Josh B., Casa, Douglas J., Reifman, Jaques

“…Objective This study aimed at assessing the risks associated with human exposure to heat-stress conditions by predicting organ- and tissue-level heat-stress…”
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Changes in Volumetric Bone Mineral Density Over 12 Months After a Tibial Bone Stress Injury Diagnosis: Implications for Return to Sports and Military Duty by Popp, Kristin L., Ackerman, Kathryn E., Rudolph, Sara E., Johannesdottir, Fjola, Hughes, Julie M., Tenforde, Adam S., Bredella, Miriam A., Xu, Chun, Unnikrishnan, Ginu, Reifman, Jaques, Bouxsein, Mary L.

“…Background: Bone stress injuries (BSIs) occur in up to 20% of runners and military personnel. Typically, after a period of unloading and gradual return to…”
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Changes in tibial bone microarchitecture in female recruits in response to 8 weeks of U.S. Army Basic Combat Training by Hughes, Julie M., Gaffney-Stomberg, Erin, Guerriere, Katelyn I., Taylor, Kathryn M., Popp, Kristin L., Xu, Chun, Unnikrishnan, Ginu, Staab, Jeffery S., Matheny, Ronald W., McClung, James P., Reifman, Jaques, Bouxsein, Mary L.

“…U.S. Army Basic Combat Training (BCT) is a physically-demanding program at the start of military service. Whereas animal studies have shown that increased…”
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Effects of body size and load carriage on lower-extremity biomechanical responses in healthy women by Unnikrishnan, Ginu, Xu, Chun, Baggaley, Michael, Tong, Junfei, Kulkarni, Sahil, Edwards, W Brent, Reifman, Jaques

“…Musculoskeletal injuries, such as stress fractures, are the single most important medical impediment to military readiness in the U.S. Army. While multiple…”
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A biomechanical-based approach to scale blast-induced molecular changes in the brain by Rubio, Jose E., Subramaniam, Dhananjay Radhakrishnan, Unnikrishnan, Ginu, Sajja, Venkata Siva Sai Sujith, Van Albert, Stephen, Rossetti, Franco, Frock, Andrew, Nguyen, Giang, Sundaramurthy, Aravind, Long, Joseph B., Reifman, Jaques

“…Animal studies provide valuable insights on how the interaction of blast waves with the head may injure the brain. However, there is no acceptable methodology…”
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The importance of modeling the human cerebral vasculature in blunt trauma by Subramaniam, Dhananjay Radhakrishnan, Unnikrishnan, Ginu, Sundaramurthy, Aravind, Rubio, Jose E, Kote, Vivek Bhaskar, Reifman, Jaques

“…Multiple studies describing human head finite element (FE) models have established the importance of including the major cerebral vasculature to improve the…”
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Investigation of the direct and indirect mechanisms of primary blast insult to the brain by Rubio, Jose E., Unnikrishnan, Ginu, Sajja, Venkata Siva Sai Sujith, Van Albert, Stephen, Rossetti, Franco, Skotak, Maciej, Alay, Eren, Sundaramurthy, Aravind, Subramaniam, Dhananjay Radhakrishnan, Long, Joseph B., Chandra, Namas, Reifman, Jaques

“…The interaction of explosion-induced blast waves with the head (i.e., a direct mechanism) or with the torso (i.e., an indirect mechanism) presumably causes…”
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Effect of specimen-specific anisotropic material properties in quantitative computed tomography-based finite element analysis of the vertebra by Unnikrishnan, Ginu U, Barest, Glenn D, Berry, David B, Hussein, Amira I, Morgan, Elise F

“…Intra- and inter-specimen variations in trabecular anisotropy are often ignored in quantitative computed tomography (QCT)-based finite element (FE) models of…”
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Cerebral Vasculature Influences Blast-Induced Biomechanical Responses of Human Brain Tissue by Subramaniam, Dhananjay Radhakrishnan, Unnikrishnan, Ginu, Sundaramurthy, Aravind, Rubio, Jose E, Kote, Vivek Bhaskar, Reifman, Jaques

“…Multiple finite-element (FE) models to predict the biomechanical responses in the human brain resulting from the interaction with blast waves have established…”
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Correlations between local strains and tissue phenotypes in an experimental model of skeletal healing by Morgan, Elise F, Salisbury Palomares, Kristy T, Gleason, Ryan E, Bellin, Daniel L, Chien, Karen B, Unnikrishnan, Ginu U, Leong, Pui L

“…Abstract Defining how mechanical cues regulate tissue differentiation during skeletal healing can benefit treatment of orthopaedic injuries and may also…”
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Elastic Anisotropy of Trabecular Bone in the Elderly Human Vertebra by Unnikrishnan, Ginu U, Gallagher, John A, Hussein, Amira I, Barest, Glenn D, Morgan, Elise F

“…Knowledge of the nature of the elastic symmetry of trabecular bone is fundamental to the study of bone adaptation and failure. Previous studies have classified…”
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A new material mapping procedure for quantitative computed tomography-based, continuum finite element analyses of the vertebra by Unnikrishnan, Ginu U, Morgan, Elise F

“…Inaccuracies in the estimation of material properties and errors in the assignment of these properties into finite element models limit the reliability,…”
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Does Blast Exposure to the Torso Cause a Blood Surge to the Brain? by Rubio, Jose E, Skotak, Maciej, Alay, Eren, Sundaramurthy, Aravind, Subramaniam, Dhananjay Radhakrishnan, Kote, Vivek Bhaskar, Yeoh, Stewart, Monson, Kenneth, Chandra, Namas, Unnikrishnan, Ginu, Reifman, Jaques

“…The interaction of explosion-induced blast waves with the torso is suspected to contribute to brain injury. In this indirect mechanism, the wave-torso…”
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Contribution of material properties of cellular components on the viscoelastic, stress-relaxation response of a cell during AFM indentation by Unnikrishnan, Ginu U., Unnikrishnan, Vinu U., Reddy, J. N.

“…The close relationship between the mechanical properties of biological cells, namely, elasticity, viscosity, and the state of its disease condition has been…”
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A 3-D Finite-Element Minipig Model to Assess Brain Biomechanical Responses to Blast Exposure by Sundaramurthy, Aravind, Kote, Vivek Bhaskar, Pearson, Noah, Boiczyk, Gregory M, McNeil, Elizabeth M, Nelson, Allison J, Subramaniam, Dhananjay Radhakrishnan, Rubio, Jose E, Monson, Kenneth, Hardy, Warren N, VandeVord, Pamela J, Unnikrishnan, Ginu, Reifman, Jaques

“…Despite years of research, it is still unknown whether the interaction of explosion-induced blast waves with the head causes injury to the human brain. One way…”
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Recent advances in the analysis of nanotube-reinforced polymeric biomaterials by Reddy J.N., Unnikrishnan Vinu U., Unnikrishnan Ginu U.

“…Conventional experimental or computational techniques are often inadequate for the analysis and development of nanocomposite-based materials as they are…”
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A 3-D virtual human model for simulating heat and cold stress by Gulati, Tushar, Hatwar, Rajeev, Unnikrishnan, Ginu, Rubio, Jose E, Reifman, Jaques

“…In this study, we extended our previously developed anatomically detailed three-dimensional (3-D) thermoregulatory virtual human model for predicting heat…”
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Effects of load carriage on biomechanical variables associated with tibial stress fractures in running by Baggaley, Michael, Esposito, Michael, Xu, Chun, Unnikrishnan, Ginu, Reifman, Jaques, Edwards, W. Brent

“…•Heavy load carriage (≥ 11.3 kg) increased loading rate and absolute free moment.•Heavy load carriage also increased rearfoot eversion and stride…”
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A cross-sectional study of the effects of load carriage on running characteristics and tibial mechanical stress: implications for stress-fracture injuries in women by Xu, Chun, Silder, Amy, Zhang, Ju, Reifman, Jaques, Unnikrishnan, Ginu

“…Load carriage is associated with musculoskeletal injuries, such as stress fractures, during military basic combat training. By investigating the influence of…”
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A 3-D Rat Brain Model for Blast-Wave Exposure: Effects of Brain Vasculature and Material Properties by Unnikrishnan, Ginu, Mao, Haojie, Sundaramurthy, Aravind, Bell, E. David, Yeoh, Stewart, Monson, Kenneth, Reifman, Jaques

“…Exposure to blast waves is suspected to cause primary traumatic brain injury. However, existing finite-element (FE) models of the rat head lack the necessary…”
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