Search Results - "Unger, M."

Systematic Review and Meta-Analysis of the Magnitude of Structural, Clinical, and Physician and Patient Barriers to Cancer Clinical Trial Participation by Unger, Joseph M, Vaidya, Riha, Hershman, Dawn L, Minasian, Lori M, Fleury, Mark E

“…Barriers to cancer clinical trial participation have been the subject of frequent study, but the rate of trial participation has not changed substantially over…”
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Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice by Unger, M S, Schernthaner, P, Marschallinger, J, Mrowetz, H, Aigner, L

“…Undoubtedly, neuroinflammation is a major contributor to Alzheimer's disease (AD) progression. Neuroinflammation is characterized by the activity of brain…”
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The BAR Domain Superfamily: Membrane-Molding Macromolecules by Frost, Adam, Unger, Vinzenz M., De Camilli, Pietro

“…Membrane-shaping proteins of the BAR domain superfamily are determinants of organelle biogenesis, membrane trafficking, cell division, and cell migration. An…”
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Structural Basis of Membrane Bending by the N-BAR Protein Endophilin by Mim, Carsten, Cui, Haosheng, Gawronski-Salerno, Joseph A., Frost, Adam, Lyman, Edward, Voth, Gregory A., Unger, Vinzenz M.

“…Functioning as key players in cellular regulation of membrane curvature, BAR domain proteins bend bilayers and recruit interaction partners through poorly…”
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The COVID-19 pandemic and new clinical trial activations by Unger, Joseph M, Xiao, Hong

“…The COVID-19 pandemic has caused severe disruptions in care for many patients. A key question is whether the landscape of clinical research has also changed…”
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Recent Results From NA61/SHINE by Unger, M.

“…We present preliminary measurements of the production spectra of identified charged pions and ρ0 production in π−+C interactions at 158 and 350 GeV/c with the…”
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Association between Body Mass Index and Cancer Survival in a Pooled Analysis of 22 Clinical Trials by Greenlee, Heather, Unger, Joseph M, LeBlanc, Michael, Ramsey, Scott, Hershman, Dawn L

“…Data are inconsistent on the association between body mass index (BMI) at time of cancer diagnosis and prognosis. We used data from 22 clinical treatment…”
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The role of soil carbon in natural climate solutions by Bossio, D. A., Cook-Patton, S. C., Ellis, P. W., Fargione, J., Sanderman, J., Smith, P., Wood, S., Zomer, R. J., von Unger, M., Emmer, I. M., Griscom, B. W.

“…Mitigating climate change requires clean energy and the removal of atmospheric carbon. Building soil carbon is an appealing way to increase carbon sinks and…”
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Sex Differences in Risk of Severe Adverse Events in Patients Receiving Immunotherapy, Targeted Therapy, or Chemotherapy in Cancer Clinical Trials by Unger, Joseph M, Vaidya, Riha, Albain, Kathy S, LeBlanc, Michael, Minasian, Lori M, Gotay, Carolyn C, Henry, N Lynn, Fisch, Michael J, Lee, Shing M, Blanke, Charles D, Hershman, Dawn L

“…Women have more adverse events (AEs) from chemotherapy than men, but few studies have investigated sex differences in immune or targeted therapies. We examined…”
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CD8+ T-cells infiltrate Alzheimer’s disease brains and regulate neuronal- and synapse-related gene expression in APP-PS1 transgenic mice by Unger, M.S., Li, E., Scharnagl, L., Poupardin, R., Altendorfer, B., Mrowetz, H., Hutter-Paier, B., Weiger, T.M., Heneka, M.T., Attems, J., Aigner, L.

“…•CD8+ T-cells infiltrate the brain in aging and human AD pathology.•CD8+ T-cells can successfully be ablated from blood and brain using an anti-CD8 antibody…”
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Comparison of Survival Outcomes Among Cancer Patients Treated In and Out of Clinical Trials by UNGER, Joseph M, BARLOW, William E, MARTIN, Diane P, RAMSEY, Scott D, LEBLANC, Michael, ETZIONI, Ruth, HERSHMAN, Dawn L

“…Clinical trials test the efficacy of a treatment in a select patient population. We examined whether cancer clinical trial patients were similar to nontrial,…”
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Effects of Subthalamic Nucleus Deep Brain Stimulation on Facial Emotion Recognition in Parkinson’s Disease: A Critical Literature Review by Fassbender, Klaus, Lochner, P., Lyros, E., Kalampokini, S., Unger, M. M.

“…Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for Parkinson’s disease (PD). Nevertheless, DBS has been associated with…”
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Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer’s Disease by Unger, M. S., Marschallinger, J., Kaindl, J., Höfling, C., Rossner, S., Heneka, Michael T., Van der Linden, A., Aigner, Ludwig

“…Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease in the Western world and is characterized by a progressive loss of cognitive functions…”
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Patient Income Level and Cancer Clinical Trial Participation by UNGER, Joseph M, HERSHMAN, Dawn L, ALBAIN, Kathy S, MOINPOUR, Carol M, PETERSEN, Judith A, BURG, Kenda, CROWLEY, John J

“…Studies have shown an association between socioeconomic status (SES) and quality of oncology care, but less is known about the impact of patient SES on…”
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Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: A multicenter study by Postuma, Ronald B., Iranzo, Alex, Hogl, Birgit, Arnulf, Isabelle, Ferini-Strambi, Luigi, Manni, Raffaele, Miyamoto, Tomoyuki, Oertel, Wolfgang, Dauvilliers, Yves, Ju, Yo-El, Puligheddu, Monica, Sonka, Karel, Pelletier, Amelie, Santamaria, Juan, Frauscher, Birgit, Leu-Semenescu, Smaranda, Zucconi, Marco, Terzaghi, Michele, Miyamoto, Masayuki, Unger, Marcus M., Carlander, Bertrand, Fantini, Maria-Livia, Montplaisir, Jacques Y.

“…Objective To assess whether risk factors for Parkinson disease and dementia with Lewy bodies increase rate of defined neurodegenerative disease in idiopathic…”
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Geographic social inequalities in information-seeking response to the COVID-19 pandemic in China: longitudinal analysis of Baidu Index by Wang, Zhicheng, Xiao, Hong, Lin, Leesa, Tang, Kun, Unger, Joseph M.

“…The outbreak of the COVID-19 pandemic alarmed the public and initiated the uptake of preventive measures. However, the manner in which the public responded to…”
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Understanding the Role of Amphipathic Helices in N-BAR Domain Driven Membrane Remodeling by Cui, Haosheng, Mim, Carsten, Vázquez, Francisco X., Lyman, Edward, Unger, Vinzenz M., Voth, Gregory A.

“…Endophilin N-BAR (N-terminal helix and Bin/amphiphysin/Rvs) domain tubulates and vesiculates lipid membranes in vitro via its crescent-shaped dimer and four…”
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Structural Basis of Membrane Invagination by F-BAR Domains by Frost, Adam, Perera, Rushika, Roux, Aurélien, Spasov, Krasimir, Destaing, Olivier, Egelman, Edward H., De Camilli, Pietro, Unger, Vinzenz M.

“…BAR superfamily domains shape membranes through poorly understood mechanisms. We solved structures of F-BAR modules bound to flat and curved bilayers using…”
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Flooding effects on soil microbial communities by Unger, Irene M., Kennedy, Ann C., Muzika, Rose-Marie

“…Flooding affects both above- and below-ground ecosystem processes. While the below-ground changes may be less obvious, they are as important as the…”
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Publisher Correction: Geographic social inequalities in information-seeking response to the COVID-19 pandemic in China: longitudinal analysis of Baidu Index by Wang, Zhicheng, Xiao, Hong, Lin, Leesa, Tang, Kun, Unger, Joseph M.

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