Search Results - "Ung, Trong Thuan"
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Metformin inhibits lithocholic acid-induced interleukin 8 upregulation in colorectal cancer cells by suppressing ROS production and NF-kB activity
Published in Scientific reports (14-02-2019)“…Metformin, an inexpensive, well-tolerated oral agent that is a commonly used first-line treatment for type 2 diabetes, has become the focus of intense research…”
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Lithocholic Acid Induces miR21, Promoting PTEN Inhibition via STAT3 and ERK-1/2 Signaling in Colorectal Cancer Cells
Published in International journal of molecular sciences (01-10-2021)“…Micro-RNA-21 (miR-21) is a vital regulator of colorectal cancer (CRC) progression and has emerged as a potential therapeutic target in CRC treatment. Our study…”
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3
Role of bile acids in colon carcinogenesis
Published in World journal of clinical cases (06-11-2018)“…Bile acids (BAs) are cholesterol derivatives synthesized in the liver and then secreted into the intestine for lipid absorption. There are numerous scientific…”
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Apigenin Suppresses the IL-1β-Induced Expression of the Urokinase-Type Plasminogen Activator Receptor by Inhibiting MAPK-Mediated AP‑1 and NF-κB Signaling in Human Bladder Cancer T24 Cells
Published in Journal of agricultural and food chemistry (25-07-2018)“…The urokinase-type plasminogen activator receptor (uPAR), a glycoprotein localized on the cell surface with a glycosylphosphatidylinositol anchor, plays a…”
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Lithocholic Acid Stimulates IL‐8 Expression in Human Colorectal Cancer Cells Via Activation of Erk1/2 MAPK and Suppression of STAT3 Activity
Published in Journal of cellular biochemistry (01-09-2017)“…ABSTRACT The secondary bile acid lithocholic acid (LCA), an established tumor promoter, has been implicated in colorectal cancer (CRC) metastasis…”
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Development of TRIB3-Based Therapy as a Gene-Independent Approach to Treat Retinal Degenerative Disorders
Published in International journal of molecular sciences (01-05-2024)“…Inherited retinal degeneration (RD) constitutes a heterogeneous group of genetic retinal degenerative disorders. The molecular mechanisms underlying RD…”
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Nicotine stimulates IL‐6 expression by activating the AP‐1 and STAT‐3 pathways in human endothelial EA.hy926 cells
Published in Journal of cellular biochemistry (01-04-2019)“…Interleukin‐6 (IL‐6), a pleiotropic cytokine, plays a key role in endothelial injury and atherosclerosis. In this study, we investigated the effects of…”
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Cholic Acid Stimulates MMP-9 in Human Colon Cancer Cells via Activation of MAPK, AP-1, and NF-κB Activity
Published in International journal of molecular sciences (12-05-2020)“…Matrix metalloproteinase-9 (MMP-9) plays a crucial role in cell invasion and cancer metastasis. In this study, we showed that cholic acid (CA), a major primary…”
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9
Carbon monoxide releasing molecule-2 ameliorates IL-1β-induced IL-8 in human gastric cancer cells
Published in Toxicology (Amsterdam) (15-06-2016)“…Abstract Carbon monoxide (CO), a byproduct of heme oxygenase (HO), presents antioxidant, anti-inflammatory, and anti-tumor properties. Accumulating evidence…”
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Prostaglandin E 2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells
Published in Molecular carcinogenesis (01-02-2017)“…Aberrant expression of urokinase-type plasminogen activator receptor (uPAR) has been observed in human gastric cancers. Prostaglandin E (PGE ), whose…”
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Prostaglandin E2 stimulates urokinase‐type plasminogen activator receptor via EP2 receptor‐dependent signaling pathways in human AGS gastric cancer cells
Published in Molecular carcinogenesis (01-02-2017)“…Aberrant expression of urokinase‐type plasminogen activator receptor (uPAR) has been observed in human gastric cancers. Prostaglandin E2 (PGE2), whose…”
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12
Lysophosphatidic Acid Upregulates Recepteur D'origine Nantais Expression and Cell Invasion via Egr-1, AP-1, and NF-κB Signaling in Bladder Carcinoma Cells
Published in International journal of molecular sciences (01-01-2020)“…Muscle invasive bladder carcinoma is a highly malignant cancer with a high mortality rate, due to its tendency to metastasize. The tyrosine kinase recepteur…”
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Preclinical Immune Response and Safety Evaluation of the Protein Subunit Vaccine Nanocovax for COVID-19
Published in Frontiers in immunology (06-12-2021)“…The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global health concern…”
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Piperine Attenuates Lithocholic Acid-Stimulated Interleukin-8 by Suppressing Src/EGFR and Reactive Oxygen Species in Human Colorectal Cancer Cells
Published in Antioxidants (10-03-2022)“…Piperine, a natural alkaloidal pungent product present in pepper plants, possesses the properties of anti-inflammatory and anti-metastasis. Lithocholic acid is…”
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Docosahexaenoic Acid Inhibits Tumor Promoter-Induced Urokinase-Type Plasminogen Activator Receptor by Suppressing PKCδ- and MAPKs-Mediated Pathways in ECV304 Human Endothelial Cells
Published in PloS one (01-09-2016)“…The overexpression of urokinase-type plasminogen activator receptor (uPAR) is associated with inflammation and virtually all human cancers. Despite the fact…”
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Role of Recepteur D'origine Nantais on Gastric Cancer Development and Progression
Published in Chonnam medical journal (01-09-2017)“…Recepteur d'origine nantais (RON) is a receptor tyrosine kinase belonging to the subfamily of which c-MET is the prototype. Large epidemiologic studies have…”
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The Involvement of Unfolded Protein Response in the Mechanism of Nitrogen Mustard-Induced Ocular Toxicity
Published in The Journal of pharmacology and experimental therapeutics (01-02-2024)“…Nitrogen mustard (NM) is a known surrogate of sulfur mustard, a chemical-warfare agent that causes a wide range of ocular symptoms, from a permanent reduction…”
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Nicotine stimulates CYP1A1 expression in human hepatocellular carcinoma cells via AP-1, NF-κB, and AhR
Published in Toxicology letters (01-10-2021)“…[Display omitted] Cytochrome P450 1A1 (CYP1A1) is a member of a subfamily of enzymes involved in the metabolism of both endogenous and exogenous substrates and…”
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Lithocholic Acid Stimulates IL-8 Expression in Human Colorectal Cancer Cells Via Activation of Erk1/2 MAPK and Suppression of STAT3 Activity: L ITHOCHOLIC A CID S TIMULATES IL-8 E XPRESSION IN H UMAN C OLORECTAL C ANCER C ELLS
Published in Journal of cellular biochemistry (01-09-2017)Get full text
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Docosahexaenoic Acid Inhibits Tumor Promoter-Induced Urokinase-Type Plasminogen Activator Receptor by Suppressing PKC[delta]- and MAPKs-Mediated Pathways in ECV304 Human Endothelial Cells
Published in PloS one (21-09-2016)“…The overexpression of urokinase-type plasminogen activator receptor (uPAR) is associated with inflammation and virtually all human cancers. Despite the fact…”
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