Search Results - "Uneuchi, Fumito"
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Design, synthesis and biological evaluation of novel pyridine derivatives as gut-selective NaPi2b inhibitors
Published in Bioorganic & medicinal chemistry letters (01-06-2022)“…[Display omitted] We previously reported thiophene derivatives as gut-selective (minimally systemic) and potent sodium-dependent phosphate transport protein 2b…”
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Design, synthesis and biological evaluation of novel indole derivatives as gut-selective NaPi2b inhibitors
Published in Bioorganic & medicinal chemistry (15-07-2022)“…[Display omitted] Intestinal sodium-dependent phosphate transport protein 2b (SLC34A2, NaPi2b) inhibitors are expected to be potential new candidates for…”
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Design, synthesis and biological evaluation of novel 1H-pyrazole-4-carbonyl-4,5,6,7-tetrahydrobenzo [b]thiophene derivatives as gut-selective NaPi2b inhibitors
Published in Bioorganic & medicinal chemistry letters (01-03-2022)“…[Display omitted] Intestinal sodium-dependent phosphate transport protein 2b (SLC34A2, NaPi2b) inhibitors are expected to be potential new candidates for…”
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4
Structure–activity relationship studies on vitamin D lactam derivatives as vitamin D receptor antagonist
Published in Bioorganic & medicinal chemistry (01-08-2008)“…Structure–activity relationship studies on 1α,25-dihydroxyvitamin D 3-26,23-lactams (DLAMs), antagonists of vitamin D, were conducted, focusing on the…”
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Lead generation from N-[benzyl(4-phenylbutyl)carbamoyl]amino acid as a novel LPA1 antagonist for the treatment of systemic sclerosis
Published in European journal of medicinal chemistry (15-11-2023)“…Lysophosphatidic acid (LPA), a bioactive phospholipid, binds to the G protein-coupled LPA1 receptor on the surfaces of immune cells, to promote progression of…”
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6
Lead generation from N-benzyl(4-phenylbutyl)carbamoylamino acid as a novel LPA1 antagonist for the treatment of systemic sclerosis
Published in European journal of medicinal chemistry (15-11-2023)“…Lysophosphatidic acid (LPA), a bioactive phospholipid, binds to the G protein-coupled LPA1 receptor on the surfaces of immune cells, to promote progression of…”
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