Search Results - "Unekawa"

HRTEM Characterization of an Age-Hardened Mg–Ca Binary Alloy by Unekawa, Mariko, Terada, Yoshihiro

“…A Mg–2.8 mass% Ca binary alloy was subjected to a homogenization treatment. The three-dimensional morphology and coherency of the Mg2Ca phase (with C14…”
Get full text

HRTEM Characterization of an Age-Hardened Mg–Ca Binary Alloy by Unekawa, Mariko, Terada, Yoshihiro

“…A Mg–2.8 mass% Ca binary alloy was subjected to a homogenization treatment. The three-dimensional morphology and coherency of the Mg2Ca phase (with C14…”
Get full text

Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant by Tang, Chunhua, Unekawa, Miyuki, Kitagawa, Satoshi, Takizawa, Tsubasa, Kayama, Yohei, Nakahara, Jin, Shibata, Mamoru

“…Cortical spreading depolarisation (CSD), the neural mechanism underlying migraine aura, may cause headache by sensitising the trigeminal system. Photophobia,…”
Get full text

Calcitonin Gene-Related Peptide mRNA Synthesis in Trigeminal Ganglion Neurons after Cortical Spreading Depolarization by Shibata, Mamoru, Kitagawa, Satoshi, Unekawa, Miyuki, Takizawa, Tsubasa, Nakahara, Jin

“…Migraine is a debilitating neurovascular disorder characterized by recurrent headache attacks of moderate to severe intensity. Calcitonin gene-related peptide…”
Get full text

Differential pial and penetrating arterial responses examined by optogenetic activation of astrocytes and neurons by Hatakeyama, Nao, Unekawa, Miyuki, Murata, Juri, Tomita, Yutaka, Suzuki, Norihiro, Nakahara, Jin, Takuwa, Hiroyuki, Kanno, Iwao, Matsui, Ko, Tanaka, Kenji F, Masamoto, Kazuto

“…A variety of brain cells participates in neurovascular coupling by transmitting and modulating vasoactive signals. The present study aimed to probe cell…”
Get full text

Three-Dimensional Morphology of C15–Al2Ca Precipitates in a Mg–Al–Ca Alloy by Kashiwase, Sakiko, Unekawa, Mariko, Hisazawa, Hiromu, Terada, Yoshihiro

“…The three-dimensional morphology and thickness of an Al2Ca Laves phase with a C15 crystal structure, which precipitated within the primary α-Mg grain of a…”
Get full text

Close association between spreading depolarization and development of infarction under experimental ischemia in anesthetized male mice by Unekawa, Miyuki, Tomita, Yutaka, Masamoto, Kazuto, Kanno, Iwao, Nakahara, Jin, Izawa, Yoshikane

“…[Display omitted] •No infarct was detected in mice without SD during experimental ischemia.•The infarct size tended to be larger in repeated SD-occurred…”
Get full text

Effect of Goreisan, a Japanese Traditional Medicine, on Cortical Spreading Depolarization in Mice by Iba, Chisato, Unekawa, Miyuki, Izawa, Yoshikane, Nakahara, Jin, Takizawa, Tsubasa

“…Goreisan, a traditional Japanese Kampo medicine, is often used to treat headaches, including migraines; however, the underlying mechanisms remain unknown…”
Get full text

Protracted hypomobility in the absence of trigeminal sensitization after cortical spreading depolarization: Relevance to migraine postdrome by Shibata, Mamoru, Kitagawa, Satoshi, Tang, Chunghua, Unekawa, Miyuki, Kayama, Yohei, Shimizu, Toshihiko, Nakahara, Jin, Suzuki, Norihiro

“…Cortical spreading depolarization (CSD) can cause prolonged hypoactivity and photophobia postdrome symptoms, which leads to protracted disability in migraine…”
Get full text

Sustained Effects of CGRP Blockade on Cortical Spreading Depolarization-Induced Alterations in Facial Heat Pain Threshold, Light Aversiveness, and Locomotive Activity in the Light Environment by Kitagawa, Satoshi, Tang, Chunhua, Unekawa, Miyuki, Kayama, Yohei, Nakahara, Jin, Shibata, Mamoru

“…A migraine is clinically characterized by repeated headache attacks that entail considerable disability. Many patients with migraines experience postdrome, the…”
Get full text

Repeated longitudinal in vivo imaging of neuro-glio-vascular unit at the peripheral boundary of ischemia in mouse cerebral cortex by Masamoto, K, Tomita, Y, Toriumi, H, Aoki, I, Unekawa, M, Takuwa, H, Itoh, Y, Suzuki, N, Kanno, I

“…Highlights ► Repeated live cell imaging at the boundary of cerebral ischemia. ► Vital staining of astrocyte with intraperitoneal injection of sulforhodamine…”
Get full text

Separate optogenetic manipulation of Nerve/glial antigen 2 (NG2) glia and mural cells using the NG2 promoter by Oishi, Mitsuhiro, Passlick, Stefan, Yamazaki, Yoshihiko, Unekawa, Miyuki, Adachi, Ruka, Yamada, Mayumi, Imayoshi, Itaru, Abe, Yoshifumi, Steinhäuser, Christian, Tanaka, Kenji F.

“…Nerve/glial antigen 2 (NG2) is a protein marker of NG2 glia and mural cells, and NG2 promoter activity is utilized to target these cells. However, the NG2…”
Get full text

Alterations in the threshold of the potassium concentration to evoke cortical spreading depression during the natural estrous cycle in mice by Ebine, Taeko, Toriumi, Haruki, Shimizu, Toshihiko, Unekawa, Miyuki, Takizawa, Tsubasa, Kayama, Yohei, Shibata, Mamoru, Suzuki, Norihiro

“…•This study explored the inducibility of CSD in the natural estrous cycle of mice.•Susceptibility to the development of CSD is elevated in the diestrus…”
Get full text

High-mobility group box 1 is an important mediator of microglial activation induced by cortical spreading depression by Takizawa, Tsubasa, Shibata, Mamoru, Kayama, Yohei, Shimizu, Toshihiko, Toriumi, Haruki, Ebine, Taeko, Unekawa, Miyuki, Koh, Anri, Yoshimura, Akihiko, Suzuki, Norihiro

“…Single episodes of cortical spreading depression (CSD) are believed to cause typical migraine aura, whereas clusters of spreading depolarizations have been…”
Get full text

Striatal Blood Flow Changes by Middle Cerebral Artery Occlusion and Its Effect on Neurological Deficits in Mice by Unekawa, Miyuki, Tsukada, Naoki, Takizawa, Tsubasa, Tomita, Yutaka, Nakahara, Jin, Izawa, Yoshikane

“…ABSTRACT Objective We attempted to record the regional cerebral blood flow (CBF) simultaneously at various regions of the cerebral cortex and the striatum…”
Get full text

Optical manipulation of local cerebral blood flow in the deep brain of freely moving mice by Abe, Yoshifumi, Kwon, Soojin, Oishi, Mitsuhiro, Unekawa, Miyuki, Takata, Norio, Seki, Fumiko, Koyama, Ryuta, Abe, Manabu, Sakimura, Kenji, Masamoto, Kazuto, Tomita, Yutaka, Okano, Hideyuki, Mushiake, Hajime, Tanaka, Kenji F.

“…An artificial tool for manipulating local cerebral blood flow (CBF) is necessary for understanding how CBF controls brain function. Here, we generate vascular…”
Get full text

Dynamic diameter response of intraparenchymal penetrating arteries during cortical spreading depression and elimination of vasoreactivity to hypercapnia in anesthetized mice by Unekawa, Miyuki, Tomita, Yutaka, Masamoto, Kazuto, Toriumi, Haruki, Osada, Takashi, Kanno, Iwao, Suzuki, Norihiro

“…Cortical spreading depression (CSD) induces marked hyperemia with a transient decrease of regional cerebral blood flow (rCBF), followed by sustained oligemia…”
Get full text

Effects of passive smoking on cortical spreading depolarization in male and female mice by Takizawa, Tsubasa, Ihara, Keiko, Unekawa, Miyuki, Iba, Chisato, Kagawa, Shizuko, Watanabe, Narumi, Nakayama, Shingo, Sakurai, Kaori, Miyazaki, Naoki, Ishida, Noriyuki, Takemura, Ryo, Shibata, Mamoru, Izawa, Yoshikane, Chubachi, Shotaro, Fukunaga, Koichi, Nakahara, Jin

“…Background Patients with migraine are typically advised to avoid passive smoking because it may aggravate headaches and other health conditions. However, there…”
Get full text

In Vivo Imaging of the Mouse Neurovascular Unit Under Chronic Cerebral Hypoperfusion by Yata, Kenichiro, Nishimura, Yuhei, Unekawa, Miyuki, Tomita, Yutaka, Suzuki, Norihiro, Tanaka, Toshio, Mizoguchi, Akira, Tomimoto, Hidekazu

“…BACKGROUND AND PURPOSE—Proper brain function is maintained by an integrated system called the neurovascular unit (NVU) comprised cellular and acellular…”
Get full text

C15–Al2Ca Precipitation in a Mg–Al–Ca Alloy by Kashiwase, Sakiko, Unekawa, Mariko, Hisazawa, Hiromu, Terada, Yoshihiro

“…The coarsening kinetics of a fine C15–Al2Ca Laves phase with a plate-like morphology precipitated within the primary α-Mg grains were investigated for…”
Get full text