Search Results - "Uneda, Shima"

Salmonella mycotic aneurysms of the external carotid artery by Hayano, Satoshi, Uneda, Shima, Kashima, Masayuki

Get full text

Retroperitoneal Bulky Histiocytic Sarcoma Successfully Treated with Induction Chemotherapy Followed by Curative Surgery by Oto, Masafumi, Maeda, Akiko, Nose, Taku, Ueda, Yujiro, Uneda, Shima, Inadome, Akito, Oshima, Koichi, Yoshida, Minoru

“…Histiocytic sarcoma (HS) is a rare hematopoietic neoplasm. We report a patient with HS treated with induction chemotherapy followed by curative surgery. A…”
Get full text

Endoglin-targeted cancer therapy by Seon, Ben K, Haba, Akinao, Matsuno, Fumihiko, Takahashi, Norihiko, Tsujie, Masanori, She, Xinwei, Harada, Naoko, Uneda, Shima, Tsujie, Tomoko, Toi, Hirofumi, Tsai, Hilda, Haruta, Yuro

“…Vascular-targeting antiangiogenic therapy (VTAT) of cancer can be advantageous over conventional tumor cell targeted cancer therapy if an appropriate target is…”
Get more information

Anti‐endoglin monoclonal antibodies are effective for suppressing metastasis and the primary tumors by targeting tumor vasculature by Uneda, Shima, Toi, Hirofumi, Tsujie, Tomoko, Tsujie, Masanori, Harada, Naoko, Tsai, Hilda, Seon, Ben K.

“…Anti‐metastatic activity of an antitumor agent is exceedingly important because metastasis is the primary cause of death for most solid cancer patients. In…”
Get full text

Prognostic Factors and Outcomes of Adult-Onset Hemophagocytic Lymphohistiocytosis: A Retrospective Analysis of 34 Cases by Oto, Masafumi, Yoshitsugu, Kanako, Uneda, Shima, Nagamine, Michiko, Yoshida, Minoru

“…Adult-onset hemophagocytic lymphohistiocytosis (HLH) has features that are distinct from that of HLH in pediatric patients. The clinical records at the…”
Get full text

Macrophage inflammatory protein‐1 alpha is produced by human multiple myeloma (MM) cells and its expression correlates with bone lesions in patients with MM by Uneda, Shima, Hata, Hiroyuki, Matsuno, Fumihiko, Harada, Naoko, Mitsuya, Yumi, Kawano, Fumio, Mitsuya, Hiroaki

“…Macrophage inflammatory protein‐1 alpha (MIP‐1α) is a chemokine primarily associated with bone absorption. We examined whether MIP‐1α was produced by purified…”
Get full text

Successful Use of Extracorporeal Membrane Oxygenation for Respiratory Failure Caused by Mediastinal Precursor T Lymphoblastic Lymphoma by Uekihara, Soichi, Uneda, Shima, Chosa, Toshiyuki, Inadomi, Kyoko, Oto, Masafumi, Yoshida, Minoru

“…Precursor T lymphoblastic lymphoma (T-LBL) often manifests as a mediastinal mass sometimes compressing vital structures like vessels or large airways. This…”
Get full text

Rapid Vanishing of Tumors by Withdrawal of Methotrexate in Epstein-Barr Virus-Related B cell Lymphoproliferative Disorder by Uneda, Shima, Sonoki, Takashi, Nakamura, Yashushi, Matsuoka, Hiroshi, Nakakuma, Hideki

Get full text

Successful treatment with liposomal doxorubicin for widespread Kaposi’s sarcoma and human herpesvirus-8 related severe hemophagocytic syndrome in a patient with acquired immunodeficiency syndrome by Uneda, Shima, Murata, Shogo, Sonoki, Takashi, Matsuoka, Hiroshi, Nakakuma, Hideki

“…Hemophagocytic syndrome (HPS) sometimes occurres in patients with acquired immunodeficiency syndrome (AIDS). Human herpesvirus-8 (HHV-8)/Kaposi’s sarcoma…”
Get full text

Antiangiogenic chimeric anti-endoglin (CD105) antibody : pharmacokinetics and immunogenicity in nonhuman primates and effects of doxorubicin by SHIOZAKI, Ken, HARADA, Naoko, GRECO, William R, HABA, Akinao, UNEDA, Shima, TSAI, Hilda, SEON, Ben K

“…We generated a human/mouse chimeric antibody c-SN6j of human IgG1 isotype from a murine anti-human endoglin (EDG) monoclonal antibody (mAb) SN6j that…”
Get full text

Aggressive CD5-positive B-cell lymphoma after remission of CD5-negative follicular lymphoma with distinct immunoglobulin heavy chain rearrangement and translocation by Sonoki, Takashi, Ishihara, Sonoko, Uneda, Shima, Hanaoka, Nobuyoshi, Kurimoto, Miwa, Matsuoka, Hiroshi, Nakakuma, Hideki

“…We report a unique, aggressive B-cell lymphoma that developed after the long-term remission of follicular lymphoma (FL). FL cells were negative for CD5,…”
Get full text

Establishment of CD5 and CD10 double-positive mature B-cell line, WILL1, showing complex 8q24 translocation involving 14q32 and 6q27 by Uneda, Shima, Gotoh, Minako, Sonoki, Takashi, Nishida, Kazuhiro, Nakamura, Yasushi, Kurimoto, Miwa, Hanaoka, Nobuyoshi, Matsuoka, Hiroshi, Taniwaki, Masafumi, Nakakuma, Hideki

“…We established a novel mature B-cell line from a CD5 and CD10 double-positive diffuse large B-cell lymphoma patient, designated as WILL1. WILL1 cells were…”
Get full text

Dehydroxymethylepoxyquinomicin, a novel nuclear factor-κB inhibitor, induces apoptosis in multiple myeloma cells in an IκBα-independent manner by Tatetsu, Hiro, Okuno, Yutaka, Nakamura, Miki, Matsuno, Fumihiko, Sonoki, Takashi, Taniguchi, Izumi, Uneda, Shima, Umezawa, Kazuo, Mitsuya, Hiroaki, Hata, Hiroyuki

“…Nuclear factor-κB (NF-κB) is constitutively activated in multiple myeloma cells. Several proteasome inhibitors have been shown to be effective against multiple…”
Get full text

Phase III study of bilayer sustained-release tramadol tablets in patients with cancer pain: a double-blind parallel-group, non-inferiority study with immediate-release tramadol capsules as an active comparator by Shinkai, Masaharu, Katsumata, Noriyuki, Kawai, Shinichi, Kuyama, Shoichi, Sasaki, Osamu, Yanagita, Yasuhiro, Yoshida, Minoru, Uneda, Shima, Tsuji, Yasushi, Harada, Hidenori, Nishida, Yasunori, Sakamoto, Yasuhiro, Himeji, Daisuke, Arioka, Hitoshi, Sato, Kazuhiro, Katsuki, Ryo, Shomura, Hiroki, Nakano, Hideshi, Ohtani, Hideaki, Sasaki, Kazutaka, Adachi, Takeshi

“…Purpose We investigated whether twice-daily administration of a bilayer tablet formulation of tramadol (35% immediate-release [IR] and 65% sustained-release)…”
Get full text

Anti‐tumor activity of an anti‐endoglin monoclonal antibody is enhanced in immunocompetent mice by Tsujie, Masanori, Tsujie, Tomoko, Toi, Hirofumi, Uneda, Shima, Shiozaki, Ken, Tsai, Hilda, Seon, Ben K.

“…In the present study, we investigated the mechanisms by which anti‐endoglin (EDG; CD105) monoclonal antibodies (mAbs) suppress angiogenesis and tumor growth…”
Get full text

Pretreatment of Low-Dose Decitabine to Leukemia Cells Markedly Enhances the Cytotoxicity of Gemtuzumab Ozogamicin by Kurimoto, Miwa, Matsuoka, Hiroshi, Hanaoka, Nobuyoshi, Uneda, Shima, Sonoki, Takashi, Nakakuma, Hideki

“…Abstract 5000 Prognosis of relapsed/refractory acute myeloid leukemia (AML) patients has been poor due to its drug resistance. Although gemtuzumab ozogamicin…”
Get full text

Effective anti-angiogenic therapy of established tumors in mice by naked anti-human endoglin (CD105) antibody : Differences in growth rate and therapeutic response between tumors growing at different sites by TSUJIE, Masanori, UNEDA, Shima, TSAI, Hilda, SEON, Ben K

“…We investigated anti-angiogenic/vascular targeting therapy of established tumors in immunocompetent mice using an anti-human endoglin (EDG; CD105) monoclonal…”
Get full text

Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells by Nakamura, Miki, Gotoh, Tomomi, Okuno, Yutaka, Tatetsu, Hiro, Sonoki, Takashi, Uneda, Shima, Mori, Masataka, Mitsuya, Hiroaki, Hata, Hiroyuki

“…The endoplasmic reticulum (ER) is an organelle in which proteins are modified. When unfolded proteins accumulate in the ER under various stresses, ER stress…”
Get full text

Receptor-targeted anticancer therapy by Seon, Ben K., Haruta, Yuro, Matsuno, Fumihiko, Haba, Akinao, Takahashi, Norihiko, She, Xinwei, Harada, Naoko, Uneda, Shima, Tsujie, Masanori, Tsujie, Tomoko, Toi, Hirofumi, Tsai, Hilda

“…ENG is a homodimeric cell membrane glycoprotein that was initially found on human leukemia cells and subsequently on endothelial cells. ENG as a target for…”
Get full text

A nitric oxide synthase inhibitor, N(G)-nitro-l-arginine-methyl-ester, exerts potent antiangiogenic effects on plasmacytoma in a newly established multiple myeloma severe combined immunodeficient mouse model by Uneda, Shima, Hata, Hiroyuki, Matsuno, Fumihiko, Nagasaki, Akitoshi, Harada, Naoko, Mitsuya, Yumi, Matsuzaki, Hiromitsu, Mitsuya, Hiroaki

“…Angiogenesis is one of critical factors in sustaining the growth, invasion and metastasis of certain solid tumours and haematological malignancies such as…”
Get full text