Search Results - "Underwood, Clare K."

Inhibition of motor neuron death in vitro and in vivo by a p75 neurotrophin receptor intracellular domain fragment by Matusica, Dusan, Alfonsi, Fabienne, Turner, Bradley J, Butler, Tim J, Shepheard, Stephanie R, Rogers, Mary-Louise, Skeldal, Sune, Underwood, Clare K, Mangelsdorf, Marie, Coulson, Elizabeth J

“…The p75 neurotrophin receptor (p75(NTR); also known as NGFR) can mediate neuronal apoptosis in disease or following trauma, and facilitate survival through…”
Get full text

Non-invasive diffusion tensor imaging detects white matter degeneration in the spinal cord of a mouse model of amyotrophic lateral sclerosis by Underwood, Clare K., Kurniawan, Nyoman D., Butler, Tim J., Cowin, Gary J., Wallace, Robyn H.

“…Amyotrophic lateral sclerosis (ALS) is characterized by selective degeneration of motor neurons. Here we examine the ability of magnetic resonance imaging…”
Get full text

Copper induced oxidation of serotonin: analysis of products and toxicity by Jones, Christopher E., Underwood, Clare K., Coulson, Elizabeth J., Taylor, Paul J.

“…Serotonin is a major neurotransmitter that controls many functions, ranging from mood and behaviour through to sleep and motor functions. The non‐enzymatic…”
Get full text

Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor by Sotthibundhu, Areechun, Sykes, Alex M, Fox, Briony, Underwood, Clare K, Thangnipon, Wipawan, Coulson, Elizabeth J

“…Alzheimer's disease is characterized by the accumulation of neurotoxic amyloidogenic peptide Abeta, degeneration of the cholinergic innervation to the…”
Get full text

The p75 neurotrophin receptor by Underwood, Clare K., Coulson, Elizabeth J.

“…The pan neurotrophin receptor (p75NTR) is best known for mediating neural cell death during development as well as in the adult following injury, the latter…”
Get full text

Palmitoylation of the C-terminal fragment of p75(NTR) regulates death signaling and is required for subsequent cleavage by gamma-secretase by Underwood, Clare K, Reid, Kate, May, Linda M, Bartlett, Perry F, Coulson, Elizabeth J

“…It has recently been shown that the p75 neurotrophin receptor (p75(NTR)), which is known to mediate neural cell death during development of the nervous system…”
Get full text

p75 Neurotrophin Receptor Mediates Neuronal Cell Death by Activating GIRK Channels through Phosphatidylinositol 4,5-Bisphosphate by Coulson, Elizabeth J, May, Linda M, Osborne, Shona L, Reid, Kate, Underwood, Clare K, Meunier, Frederic A, Bartlett, Perry F, Sah, Pankaj

“…The pan neurotrophin receptor p75(NTR) signals programmed cell death both during nervous system development and after neural trauma and disease in the adult…”
Get full text

XANES investigation of the Co oxidation state in solution and in cancer cells treated with Co(III) complexes by Bonnitcha, Paul D., Hall, Matthew D., Underwood, Clare K., Foran, Garry J., Zhang, Mei, Beale, Philip J., Hambley, Trevor W.

“…XANES spectroscopy has been used to investigate whether it is possible to determine the oxidation state and coordination environment of Co complexes following…”
Get full text

β-Amyloid1–42 Induces Neuronal Death through the p75 Neurotrophin Receptor by Sotthibundhu, Areechun, Sykes, Alex M., Fox, Briony, Underwood, Clare K., Thangnipon, Wipawan, Coulson, Elizabeth J.

“…Alzheimer's disease is characterized by the accumulation of neurotoxic amyloidogenic peptide Aβ, degeneration of the cholinergic innervation to the hippocampus…”
Get full text

β-Amyloid 1–42 Induces Neuronal Death through the p75 Neurotrophin Receptor by Sotthibundhu, Areechun, Sykes, Alex M., Fox, Briony, Underwood, Clare K., Thangnipon, Wipawan, Coulson, Elizabeth J.

“…Alzheimer's disease is characterized by the accumulation of neurotoxic amyloidogenic peptide Aβ, degeneration of the cholinergic innervation to the hippocampus…”
Get full text

beta -Amyloid sub(1-42) Induces Neuronal Death through the p75 Neurotrophin Receptor by Sotthibundhu, Areechun, Sykes, Alex M, Fox, Briony, Underwood, Clare K, Thangnipon, Wipawan, Coulson, Elizabeth J

“…Alzheimer's disease is characterized by the accumulation of neurotoxic amyloidogenic peptide A beta , degeneration of the cholinergic innervation to the…”
Get full text

Palmitoylation of the C-terminal fragment of p75NTR regulates death signaling and is required for subsequent cleavage by γ-secretase by Underwood, Clare K., Reid, Kate, May, Linda M., Bartlett, Perry F., Coulson, Elizabeth J.

Get full text

Palmitoylation of the C-terminal fragment of p75 NTR regulates death signaling and is required for subsequent cleavage by γ-secretase by Underwood, Clare K., Reid, Kate, May, Linda M., Bartlett, Perry F., Coulson, Elizabeth J.

“…It has recently been shown that the p75 neurotrophin receptor (p75 NTR), which is known to mediate neural cell death during development of the nervous system…”
Get full text

Can metal complexes serve as hypoxia activated prodrugs? Investigations of a Co(III) complex of the MMP inhibitor marimastat by Failes, Timothy W., Diakos, Connie I., Underwood, Clare K., Hambley, Trevor W., Cullinane, Carleen M., Guy Lyons, J.

Get full text

{beta}-Amyloid1-42 Induces Neuronal Death through the p75 Neurotrophin Receptor by Sotthibundhu, Areechun, Sykes, Alex M, Fox, Briony, Underwood, Clare K, Thangnipon, Wipawan, Coulson, Elizabeth J

Get full text