Search Results - "Underwood, Charles J"
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Engineering Apomixis: Clonal Seeds Approaching the Fields
Published in Annual review of plant biology (20-05-2022)“…Apomixis is a form of reproduction leading to clonal seeds and offspring that are genetically identical to the maternal plant. While apomixis naturally occurs…”
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GenomeScope: fast reference-free genome profiling from short reads
Published in Bioinformatics (Oxford, England) (15-07-2017)“…GenomeScope is an open-source web tool to rapidly estimate the overall characteristics of a genome, including genome size, heterozygosity rate and repeat…”
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Epigenetic activation of meiotic recombination near Arabidopsis thaliana centromeres via loss of H3K9me2 and non-CG DNA methylation
Published in Genome research (01-04-2018)“…Eukaryotic centromeres contain the kinetochore, which connects chromosomes to the spindle allowing segregation. During meiosis, centromeres are suppressed for…”
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Genetic and epigenetic variation of transposable elements in Arabidopsis
Published in Current opinion in plant biology (01-04-2017)“…•Natural Arabidopsis accessions exhibit genetic and epigenetic variation of TEs.•Variable enrichment of TE classes in euchromatin, pericentromeres and…”
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Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions
Published in Genome research (01-04-2018)“…Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11 topoisomerase-like complexes. Meiotic DSB frequency varies extensively…”
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Natural variation and dosage of the HEI10 meiotic E3 ligase control Arabidopsis crossover recombination
Published in Genes & development (01-02-2017)“…During meiosis, homologous chromosomes undergo crossover recombination, which creates genetic diversity and balances homolog segregation. Despite these…”
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Selective Methylation of Histone H3 Variant H3.1 Regulates Heterochromatin Replication
Published in Science (American Association for the Advancement of Science) (14-03-2014)“…Histone variants have been proposed to act as determinants for posttranslational modifications with widespread regulatory functions. We identify a…”
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Recombination Rate Heterogeneity within Arabidopsis Disease Resistance Genes
Published in PLoS genetics (01-07-2016)“…Meiotic crossover frequency varies extensively along chromosomes and is typically concentrated in hotspots. As recombination increases genetic diversity,…”
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Apomixis
Published in Current biology (24-04-2023)“…Wang and Underwood introduce apomixis in plants…”
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10
Heterogeneous transposable elements as silencers, enhancers and targets of meiotic recombination
Published in Chromosoma (01-09-2019)“…During meiosis, DNA double-strand breaks are initiated by the topoisomerase-like enzyme SPO11 and are repaired by inter-sister chromatid and inter-homologue…”
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A new Oligocene site with terrestrial mammals and a selachian fauna from Minqar Tibaghbagh, the Western Desert of Egypt
Published in Acta palaeontologica Polonica (01-09-2017)“…A new fossil site at Minqar Tibaghbagh, east of Siwa, in the Egyptian Western Desert is described. This represents the first place in Egypt outside the Fayum…”
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Meiosis in crops: from genes to genomes
Published in Journal of experimental botany (30-09-2021)“…Meiosis generates genetic diversity in natural populations and during breeding. We review meiosis research in major crop species, including an in-depth…”
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Massive crossover elevation via combination of HEI10 and recq4a recq4b during Arabidopsis meiosis
Published in Proceedings of the National Academy of Sciences - PNAS (06-03-2018)“…During meiosis, homologous chromosomes undergo reciprocal crossovers, which generate genetic diversity and underpin classical crop improvement. Meiotic…”
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14
A PARTHENOGENESIS allele from apomictic dandelion can induce egg cell division without fertilization in lettuce
Published in Nature genetics (01-01-2022)“…Apomixis, the clonal formation of seeds, is a rare yet widely distributed trait in flowering plants. We have isolated the PARTHENOGENESIS ( PAR ) gene from…”
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Harnessing clonal gametes in hybrid crops to engineer polyploid genomes
Published in Nature genetics (01-06-2024)“…Heterosis boosts crop yield; however, harnessing additional progressive heterosis in polyploids is challenging for breeders. We bioengineered a ‘mitosis…”
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Technology-driven approaches for meiosis research in tomato and wild relatives
Published in Plant reproduction (01-03-2023)“…Meiosis is a specialized cell division during reproduction where one round of chromosomal replication is followed by genetic recombination and two rounds of…”
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A chromosome scale tomato genome built from complementary PacBio and Nanopore sequences alone reveals extensive linkage drag during breeding
Published in The Plant journal : for cell and molecular biology (01-04-2022)“…SUMMARY The assembly and scaffolding of plant crop genomes facilitate the characterization of genetically diverse cultivated and wild germplasm. The cultivated…”
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The emerging role of small RNAs in ovule development, a kind of magic
Published in Plant reproduction (01-12-2021)“…In plants, small RNAs have been recognized as key genetic and epigenetic regulators of development. Small RNAs are usually 20 to 30 nucleotides in length and…”
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Natural variation identifies SNI1, the SMC5/6 component, as a modifier of meiotic crossover in Arabidopsis
Published in Proceedings of the National Academy of Sciences - PNAS (17-08-2021)“…The frequency and distribution of meiotic crossovers are tightly controlled; however, variation in this process can be observed both within and between…”
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Argonautes team up to silence transposable elements in Arabidopsis
Published in The EMBO journal (04-03-2015)“…The de novo silencing of transposable elements in plants and animals is mediated in part by RNA‐directed chromatin modification. In flowering plants, AGO4 has…”
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