Search Results - "Unal, Durisehvar"
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Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice
Published in Nature communications (08-11-2022)“…Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous CRY1 in mammals…”
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Gene doping in sports
Published in Sports medicine (Auckland) (01-01-2004)“…Gene or cell doping is defined by the World Anti-Doping Agency (WADA) as "the non-therapeutic use of genes, genetic elements and/or cells that have the…”
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3
Analgesic efficacy of wound infiltration with tramadol after cesarean delivery under general anesthesia: Randomized trial
Published in The journal of obstetrics and gynaecology research (01-07-2016)“…Aim To examine whether tramadol wound infiltration decreased postoperative pain following cesarean section (CS) under general anesthesia or reduced the need…”
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Food Effect on Bioavailability of Modified-Release Trimetazidine Tablets
Published in Journal of clinical pharmacology (01-10-2012)“…This study aimed to investigate a food effect on the bio-availability of modified-release (MR) trimetazidine tablets in 36 healthy volunteers. Trimetazidine,…”
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Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets
Published in Cellular signalling (01-10-2010)“…The Wnt signaling pathway is involved in many differentiation events during embryonic development and can lead to tumor formation after aberrant activation of…”
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A validated method without derivatization for the determination of Letrozole by high performance liquid chromatography-fluorimetric method for pharmaceutical preparation
Published in Istanbul journal of pharmacy (09-10-2019)“…A high performance liquid chromatography method has been developed for determination of letrozole in tablets. The method has developed in reverse phase column…”
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7
Escitalopram co-prescription in anastrozole-treated breast cancer patients
Published in Northern Clinics of Istanbul (01-01-2022)“…OBJECTIVE: The purpose of the study was to evaluate the impact of escitalopram co-prescription on plasma anastrozole levels in post-menopausal breast cancer…”
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Comparative study of cytotoxic activities, DNA binding and molecular docking interactions of anticancer agent epirubicin and its novel copper complex
Published in Journal of molecular structure (15-05-2021)“…•The synthesis of copper(II) complex of anticancer agent Epirubicin.•It has been investigated whether complex will exhibit cytotoxic activity.•DNA binding…”
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Comparative vascular effects of levetiracetam and valproate with hyperhomocysteinemia in rat models
Published in Türk biyokimya dergisi (29-04-2024)“…Hyperhomocysteinemia (HHcy) a significant risk factor for vascular disease, often emerges in epilepsy with the use of antiepileptic drugs. In this…”
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Capsaicin determination from pain patch for the calculation of Scoville heat units by gas chromatography-mass spectrometry
Published in Istanbul journal of pharmacy (01-12-2021)“…Background and Aims: A sensitive, accurate and precise method has been developed for the determination of Capsaicin from pain patches by Gas chromatography…”
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A Simple and Rapid LC-MS/MS Method for Therapeutic Drug Monitoring of Lenalidomide
Published in Pakistan journal of analytical and environmental chemistry (30-06-2020)“…Immunomodulatory drugs lenalidomide (LENA) and pomalidomide (POMA) are synthetic compounds derived by modifying the chemical structure of thalidomide to…”
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Core shell column in high-performance liquid chromatography for the determination of polar compounds; troxerutin and carbazochrome
Published in Istanbul journal of pharmacy (01-04-2020)“…Background and Aims: The combination of troxerutin and carbazochrome has been found efficacious for non-surgical patients with acute uncomplicated hemorrhoids…”
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13
Purine Nucleoside Phosphorylase Deficiency in a Patient With Spastic Paraplegia and Recurrent Infections
Published in Journal of child neurology (01-06-2007)“…Purine nucleoside phosphorylase deficiency is a rare autosomal recessive immunodeficiency disease. The characteristic features of the disease include severe T…”
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Correction to: The Effect of Hydroxy Metabolites of Clarithromycin to the Pharmacokinetic Parameters, and Determination of Hydroxy Metabolites Ratio of Clarithromycin
Published in European journal of drug metabolism and pharmacokinetics (2021)“…The following article was unintentionally published twice in European Journal of Drug Metabolism and Pharmacokinetics…”
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Clinical study on the bioequivalence of two tablet formulations of flurbiprofen
Published in European journal of drug metabolism and pharmacokinetics (01-01-2009)“…Summary Flurbiprofen (CAS 5104-49-4) is a member of phenylaikanoic acid derivative group of nonsteroid anti-inflammatory drugs. It exhibits anti-inflammatory,…”
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16
Investigation of serum leptin levels in professional male football players and healthy sedentary males
Published in Neuro-endocrinology letters (01-04-2005)“…In the present study we aimed at investigating leptin levels in professional male athletes who have been exercising regularly for a long time and leptin levels…”
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The effect of hydroxy metabolites of clarithromycin to the pharmacokinetic parameters, and determination of hydroxy metabolites ratio of clarithromycin
Published in European journal of drug metabolism and pharmacokinetics (01-10-2008)“…Summary Clarithromycin is a broad-spectrum macrolide antibacterial agent which is effective both in vitro and in vivo against the major pathogens responsible…”
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The Relation Between Serum Leptin Levels and Max VO 2 in Male Patients with Type I Diabetes and Healthy Sedentary Males
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The Relation Between Serum Leptin Levels and Max VO2 in Male Patients with Type I Diabetes and Healthy Sedentary Males
Published in Endocrine research (01-01-2004)“…This study aimed at investigating leptin levels in male diabetes type I patients who were on insulin treatment and also healthy sedentary males. The study…”
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The effect of hydroxy metabolites of clarithromycin to the pharmacokinetic parameters, and determination of hydroxy metabolites ratio of clarithromycin
Published in European journal of drug metabolism and pharmacokinetics (01-01-2009)“…Summary Clarithromycin is a broad-spectrum macrolide antibacterial agent which is effective both in vitro and in vivo against the major pathogens responsible…”
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