Search Results - "Umrao, Deepmala"

Docosahexaenoic acid modulates brain-derived neurotrophic factor via GPR40 in the brain and alleviates diabesity-associated learning and memory deficits in mice by Sona, Chandan, Kumar, Ajeet, Dogra, Shalini, Kumar, Boda Arun, Umrao, Deepmala, Yadav, Prem N.

“…GPR40 (Free fatty acid receptor 1) has emerged as an important therapeutic target for diabetes. Several studies have demonstrated the association of comorbid…”
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Chronic histamine 3 receptor antagonism alleviates depression like conditions in mice via modulation of brain-derived neurotrophic factor and hypothalamus-pituitary adrenal axis by Kumar, Ajeet, Dogra, Shalini, Sona, Chandan, Umrao, Deepmala, Rashid, Mamunur, Singh, Sandeep K, Wahajuddin, Muhammad, Yadav, Prem N

“…•Chronic H3R antagonism alleviates CUS induced depression-like phenotypes.•Chronic treatment of H3R antagonist increases BDNF expression in PFC and hippocampus…”
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Chronic Kappa opioid receptor activation modulates NR2B: Implication in treatment resistant depression by Dogra, Shalini, Kumar, Ajeet, Umrao, Deepmala, Sahasrabuddhe, Amogh A., Yadav, Prem N.

“…Psychotomimetic and prodepressive effect by kappa opioid receptor (KOR) activation in rodents and human is widely known. Significantly, recent clinical…”
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Novel Tetrahydroquinazolinamines as Selective Histamine 3 Receptor Antagonists for the Treatment of Obesity by Kumar, Ajeet, Pasam, Venkata Reddy, Thakur, Ravi Kumar, Singh, Maninder, Singh, Kartikey, Shukla, Mahendra, Yadav, Anubhav, Dogra, Shalini, Sona, Chandan, Umrao, Deepmala, Jaiswal, Swati, Ahmad, Hafsa, Rashid, Mamunur, Singh, Sandeep K, Wahajuddin, Muhammad, Dwivedi, Anil Kumar, Siddiqi, Mohammad Imran, Lal, Jawahar, Tripathi, Rama Pati, Yadav, Prem N

“…The histamine 3 receptor (H3R) is a presynaptic receptor, which modulates several neurotransmitters including histamine and various essential physiological…”
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Opioid Receptor Modulators with a Cinnamyl Group by Ravilla, Lokesh, Venkata subba Naidu, N, Dogra, Shalini, Umrao, Deepmala, Yadav, Prem N, Biswas, Ansuman, Michael, Daliah, Sekar, Kanagaraj, Nagarajan, Kuppuswamy

“…To obtain selective and potent opioid receptor ligands, we synthesized dehydro derivatives of alvimopan and found compound (28f), a selective but modest…”
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