Search Results - "Umemura, Hiroshi"

Current Status of Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight Mass Spectrometry (MALDI-TOF MS) in Clinical Diagnostic Microbiology by Tsuchida, Sachio, Umemura, Hiroshi, Nakayama, Tomohiro

“…Mass spectrometry (MS), a core technology for proteomics and metabolomics, is currently being developed for clinical applications. The identification of…”
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Regulation of programmed cell death ligand 1 expression by atypical protein kinase C lambda/iota in cutaneous angiosarcoma by Kawamura, Ai, Kawamura, Takuji, Riddell, Meghan, Hikita, Takao, Yanagi, Teruki, Umemura, Hiroshi, Nakayama, Masanori

“…The expression of immune checkpoint proteins such as programmed cell death protein 1 (PD‐1) and its ligand (PD‐L1) has been shown to correlate with patient…”
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Elucidation of the Mechanism and Significance of the Erythrocyte Sedimentation Rate from Clinical Laboratory Data by Umemura, Hiroshi, Fukuda, Yoshiaki, Miyashita, Tetsuo, Nakayama, Tomohiro

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Evaluation of a novel sample preparation method for identifying Aspergillus fumigatus using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: Combining Yatalase and silica beads treatment by Tsuchida, Sachio, Yamashita, Koji, Murata, Syota, Miyabe, Akiko, Satoh, Mamoru, Matsushita, Kazuyuki, Nakayama, Tomohiro, Nomura, Fumio, Umemura, Hiroshi

“…Aspergillus spp. belong to filamentous fungi and sometimes cause invasive aspergillosis which has high mortality. Filamentous fungi are generally identified…”
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Sex differences in the evaluation of proteinuria using the urine dipstick test by Kojima, Chiari, Umemura, Hiroshi, Shimosawa, Tatsuo, Nakayama, Tomohiro

“…The urine protein dipstick test is widely used, but false-positive and false-negative results may occur. This study aimed to compare the urine protein dipstick…”
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aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability by Riddell, Meghan, Nakayama, Akiko, Hikita, Takao, Mirzapourshafiyi, Fatemeh, Kawamura, Takuji, Pasha, Ayesha, Li, Mengnan, Masuzawa, Mikio, Looso, Mario, Steinbacher, Tim, Ebnet, Klaus, Potente, Michael, Hirose, Tomonori, Ohno, Shigeo, Fleming, Ingrid, Gattenlöhner, Stefan, Aung, Phyu P., Phung, Thuy, Yamasaki, Osamu, Yanagi, Teruki, Umemura, Hiroshi, Nakayama, Masanori

“…Strict regulation of proliferation is vital for development, whereas unregulated cell proliferation is a fundamental characteristic of cancer. The polarity…”
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Comparative study on driver mutations in primary and metastatic melanomas at a single Japanese institute: A clue for intra- and inter-tumor heterogeneity by Kaji, Tatsuya, Yamasaki, Osamu, Takata, Minoru, Otsuka, Masaki, Hamada, Toshihisa, Morizane, Shin, Asagoe, Kenji, Yanai, Hiroyuki, Hirai, Yoji, Umemura, Hiroshi, Iwatsuki, Keiji

“…Highlights • In the present paper, we analyzed driver mutations of 77 melanoma tissue samples from 60 patients, focusing on the intra-tumor mutational…”
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Leukocytoclastic vasculitis associated with immunoglobulin A lambda monoclonal gammopathy of undetermined significance: A case report and review of previously reported cases by Umemura, Hiroshi, Yamasaki, Osamu, Iwatsuki, Keiji

“…Leukocytoclastic vasculitis is often associated with immunoglobulin (Ig)A deposition on the vascular walls. IgA‐associated leukocytoclastic vasculitis…”
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A Case-Control Study of the APELA Gene and Hypertensive Disorders of Pregnancy by Shimada, Naomi, Nakayama, Tomohiro, Umemura, Hiroshi, Kawana, Kei, Yamamoto, Tatsuo, Uchigasaki, Seisaku

“…Hypertensive disorders of pregnancy (HDPs) are believed to comprise a group of multifactorial genetic diseases. Recently, it was reported that -knockout mice…”
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Usefulness of serum 5‐S‐cysteinyl‐dopa as a biomarker for predicting prognosis and detecting relapse in patients with advanced stage malignant melanoma by Umemura, Hiroshi, Yamasaki, Osamu, Kaji, Tatsuya, Otsuka, Masaki, Asagoe, Kenji, Takata, Minoru, Iwatsuki, Keiji

“…With the recent development of novel molecular targeted drugs for advanced stage malignant melanoma (MM), including RAF and mitogen‐activated protein kinase…”
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Two cases of metallic foreign bodies hidden in recalcitrant wounds unexpectedly detected using magnetic resonance imaging by Tachibana, Kota, Umemura, Hiroshi, Morizane, Shin, Yamasaki, Osamu

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Proteomic analysis of gingival crevicular fluid for discovery of novel periodontal disease markers by Tsuchida, Sachio, Satoh, Mamoru, Umemura, Hiroshi, Sogawa, Kazuyuki, Kawashima, Yusuke, Kado, Sayaka, Sawai, Setsu, Nishimura, Motoi, Kodera, Yoshio, Matsushita, Kazuyuki, Nomura, Fumio

“…The protein composition of gingival crevicular fluid (GCF) may reflect the pathophysiology of periodontal diseases. A standard GCF proteomic pattern of healthy…”
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Identification of a Novel ACVRL1 Gene Mutation (c.100T>A, p.Cys34Ser) in a Japanese Patient with Possible Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu Disease) by Umemura, Hiroshi, Miura, Katsuhiro, Naruse, Hiromu, Hatta, Yoshihiro, Takei, Masami, Nakayama, Tomohiro

“…Hereditary hemorrhagic telangiectasia (HHT; also known as Osler-Weber-Rendu disease) is an autosomal dominant genetic disorder that causes frequent epistaxis,…”
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Serum Carcinoembryonic Antigen Level as a Marker for Advanced Stage and Chemotherapeutic Response in Extramammary Paget's Disease by Umemura, Hiroshi, Yamasaki, Osamu, Kaji, Tatsuya, Otsuka, Masaki, Asagoe, Kenji, Iwatsuki, Keiji

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Identification of a high molecular weight kininogen fragment as a marker for early gastric cancer by serum proteome analysis by Umemura, Hiroshi, Togawa, Akira, Sogawa, Kazuyuki, Satoh, Mamoru, Mogushi, Kaoru, Nishimura, Motoi, Matsushita, Kazuyuki, Tanaka, Hiroshi, Takizawa, Hirotaka, Kodera, Yoshio, Nomura, Fumio

“…Background Serum biomarkers currently available for gastric cancers are not sufficiently sensitive and specific. Methods We used matrix-assisted laser…”
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Eumycetoma caused by Trichophyton species successfully treated with terbinafine and surgery by Namba, Hiroko D., Umemura, Hiroshi, Asagoe, Kenji

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Attitudes toward and current status of disclosure of secondary findings from next-generation sequencing: a nation-wide survey of clinical genetics professionals in Japan by Tsuchiya, Mio, Yamada, Takahiro, Akaishi, Rina, Hamanoue, Haruka, Hirasawa, Akira, Hyodo, Maki, Imoto, Issei, Kosho, Tomoki, Kurosawa, Kenji, Murakami, Hiromi, Nakatani, Kaname, Nomura, Fumio, Sasaki, Aiko, Shimizu, Kenji, Tamai, Mariko, Umemura, Hiroshi, Watanabe, Atsushi, Yoshida, Akiko, Yoshihashi, Hiroshi, Yotsumoto, Junko, Kosugi, Shinji

“…The management of secondary findings (SFs), which are beyond the intended purpose of the analysis, from clinical comprehensive genomic analysis using next…”
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Spindle cell squamous cell carcinoma arising from chronic osteomyelitis by Umemura, Hiroshi, Hamashige, Jumpei, Yamada, Kazuki, Yamadori, Ichiro, Asagoe, Kenji

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Prognostic value of 18F‐fluorodeoxyglucose positron emission tomography/computed tomography in patients with cutaneous angiosarcoma: A retrospective study of 18 cases by Umemura, Hiroshi, Yamasaki, Osamu, Kaji, Tatsuya, Hamada, Toshihisa, Otsuka, Masaki, Asagoe, Kenji, Iwatsuki, Keiji

“…Cutaneous angiosarcoma (CAS) is a rare soft tissue sarcoma with rapid growth and poor prognosis. We retrospectively analyzed the data of 18 patients with CAS…”
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Reducing the Incidence of Pseudohyperkalemia by Avoiding Making a Fist During Phlebotomy: A Quality Improvement Report by Seimiya, Masanori, PhD, Yoshida, Toshihiko, BSc, Sawabe, Yuji, BHSc, Sogawa, Kazuyuki, PhD, Umemura, Hiroshi, MD, PhD, Matsushita, Kazuyuki, MD, PhD, Nomura, Fumio, MD, PhD

“…Background Pseudohyperkalemia is uncommon, but important. Local release of potassium caused by contraction of the forearm muscles from a tightly clenched fist…”
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