Search Results - "Umemoto, Atsushi"

Proteomic alteration in gastic adenocarcinomas from Japanese patients by Yoshihara, Takahiro, Kadota, Yoshito, Yoshimura, Yoshiyuki, Tatano, Yutaka, Takeuchi, Naohiro, Okitsu, Hiroshi, Umemoto, Atsushi, Yamauchi, Takashi, Itoh, Kohji

“…Gastric adenocarcinomas comprise one of the common types of cancers in Asian countries including Japan. Comprehensive protein profiling of paired surgical…”
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Preoperative chemotherapy with weekly docetaxel plus low-dose cisplatin and 5-fluorouracil for stage II/III squamous cell carcinoma of the esophagus by Yoshida, Takahiro, Seike, Junichi, Miyoshi, Takanori, Yamai, Hiromichi, Takechi, Hirokazu, Yuasa, Yasuhiro, Furukita, Yoshihito, Yamamoto, Yota, Umemoto, Atsushi, Tangoku, Akira

“…Background Docetaxel is a powerful anticancer agent for esophageal cancer. Preoperative combined chemotherapy with weekly docetaxel plus low-dose cisplatin and…”
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A case of early relapsed multiple lung metastases after esophagectomy successfully treated with S-1/cisplatin therapy after docetaxel/5-fluorouracil/cisplatin therapy by Seike, Junichi, Yoshida, Takahiro, Honda, Junko, Miyoshi, Takanori, Umemoto, Atsushi, Tangoku, Akira

“…A 55-year-old-male patient underwent subtotal esophagectomy for esophageal cancer (pT1b, N0, M0, stage II) in April 2005. The patient received postoperative…”
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Effects of dietary bile acids on formation of azoxymethane-induced aberrant crypt foci in F344 rats by Seraj, Mohammed Jabed, Umemoto, Atsushi, Kajikawa, Aiichiro, Mimura, Seiji, Kinouchi, Takemi, Ohnishi, Yoshinari, Monden, Yasumasa

“…The present study has demonstrated the influence of bile acids (BAs) on the development and growth of azoxymethane (AOM)-induced aberrant crypt foci (ACF)…”
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An elderly case of advanced cervical esophageal cancer successfully treated with UFT after chemoradiotherapy with docetaxel/5-FU/CDDP by Seike, Junichi, Yoshida, Takahiro, Honda, Junko, Miyoshi, Takanori, Umemoto, Atsushi, Tangoku, Akira

“…An 80-year-old woman with advanced cervical esophageal cancer underwent chemoradiotherapy with docetaxel/5-FU/CDDP (DFP). The tumor reduced in size after the…”
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Effect of ursodeoxycholic acid on azoxymethane-induced aberrant crypt foci formation in rat colon: in vitro potential role of intracellular Ca2 by Momen, Mohammed Abdul, Monden, Yasumasa, Houchi, Hitoshi, Umemoto, Atsushi

“…The studies were conducted to examine the precise nature of the suppressive effect of ursodeoxycholic acid (UDCA) on colonic aberrant crypt foci (ACF)…”
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DNA adduct formation by 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) in rat colon by Lin, C X, Monden, Y, Umemoto, A

“…A food-born carcinogen, 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) induces cancer in the rat colon. The mechanism for colonic DNA adduct formation leading…”
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Antiestrogens and the Formation of DNA Damage in Rats:  A Comparison by Kim, Sung Yeon, Suzuki, Naomi, Laxmi, Y. R. Santosh, Umemoto, Atsushi, Matsuda, Tomonari, Shibutani, Shinya

“…Tamoxifen (TAM) has been used as an agent for the treatment and prevention of breast cancer. However, long-term treatment of TAM in women increases the risk of…”
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Binding of Orally given 2-Amino-6-methyldipyrido [1, 2-a: 3', 2'-d] imidazole, a Carcinogen, to Rat Hemoglobin by UMEMOTO, Atsushi, NEGISHI, Chie, SATO, Shigeaki, SUGIMURA, Takashi

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Determination of Tamoxifen−DNA Adducts in Leukocytes from Breast Cancer Patients Treated with Tamoxifen by Umemoto, Atsushi, Monden, Yasumasa, Lin, Chun-Xing, Momen, Md. Abdul, Ueyama, Yuji, Komaki, Kansei, Laxmi, Y. R. Santosh, Shibutani, Shinya

“…Tamoxifen (TAM), a widely used antiestrogen for breast cancer therapy and chemoprevention, increases the incidence of endometrial cancer in women. The…”
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Absence of DNA Adduct in the Leukocytes from Breast Cancer Patients Treated with Toremifene by Umemoto, Atsushi, Lin, Chun-Xing, Ueyama, Yuji, Komaki, Kansei, Santosh Laxmi, Y. R, Shibutani, Shinya

“…Tamoxifen (TAM) causes cancer in rat liver and human endometrium, whereas the carcinogenicity of its chlorinated analogue toremifene (TOR) has not been…”
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Jejunal extramedullary plasmacytoma by Okamura, Seisuke, Tsujigami, Koji, Muguruma, Naoki, Ito, Susumu, Wakatsuki, Shingo, Sano, Toshiaki, Umemoto, Atsushi, Urakami, Yoshihito

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Identification of hepatic tamoxifen-DNA adducts in mice: (alpha)-(N(2)-deoxyguanosinyl)tamoxifen and (alpha)-(N(2)-deoxyguanosinyl)tamoxifen N-oxide by Umemoto, Atsushi, Monden, Yasumasa, Suwa, Masato, Kanno, Yoshikazu

“…Tamoxifen-DNA adducts detected in the liver of mice treated with tamoxifen have not yet been identified. In the present study a new type of tamoxifen-DNA…”
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Identification and Quantification of Tamoxifen-DNA Adducts in the Liver of Rats and Mice by Umemoto, Atsushi, Komaki, Kansei, Monden, Yasumasa, Suwa, Masato, Kanno, Yoshikazu, Kitagawa, Masayuki, Suzuki, Masanobu, Lin, Chun-Xing, Ueyama, Yuji, Momen, Md. Abdul, Ravindernath, Anisetti, Shibutani, Shinya

“…A new HPLC gradient system was developed for 32P-postlabeling analysis to identify and quantify hepatic tamoxifen−DNA adducts of rats and mice treated with…”
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Identification of hepatic tamoxifen–DNA adducts in mice: α-(N2-deoxyguanosinyl)tamoxifen and α-(N2-deoxyguanosinyl)tamoxifen N-oxide by Umemoto, Atsushi, Monden, Yasumasa, Suwa, Masato, Kanno, Yoshikazu, Suzuki, Masanobu, Lin, Chun-Xing, Ueyama, Yuji, Momen, Md.Abdul, Ravindernath, Anisetti, Shibutani, Shinya, Komaki, Kansei

“…Tamoxifen–DNA adducts detected in the liver of mice treated with tamoxifen have not yet been identified. In the present study a new type of tamoxifen–DNA…”
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Identification of Tamoxifen−DNA Adducts Induced by α-Acetoxy-N-desmethyltamoxifen by Kitagawa, Masayuki, Ravindernath, Anisetti, Suzuki, Naomi, Rieger, Robert, Terashima, Isamu, Umemoto, Atsushi, Shibutani, Shinya

“…Treatment with tamoxifen increased the risk of endometrial cancers in breast cancer patients and women participating in the chemoprevention study. In our…”
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Effect of bile acids on formation of azoxymethane-induced aberrant crypt foci in colostomized F344 rat colon by Lin, Chun-Xing, Umemoto, Atsushi, Jabed Seraj, Mohammed, Mimura, Seiji, Monden, Yasumasa

“…The effect of bile acids on the formation of azoxymethane induced aberrant crypt foci (ACF) was investigated using the fecal stream-excluded colons of…”
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Tamoxifen−DNA Adducts Formed by α-Acetoxytamoxifen N-Oxide by Umemoto, Atsushi, Monden, Yasumasa, Komaki, Kansei, Suwa, Masato, Kanno, Yoshikazu, Suzuki, Masanobu, Lin, Chun-Xing, Ueyama, Yuji, Momen, Md. Abdul, Ravindernath, Anisetti, Shibutani, Shinya

“…DNA adduct formation is assumed to be a major carcinogenic event, leading to the development of endometrial cancer in breast cancer patients taking tamoxifen…”
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In vitro formation of DNA adducts with bile acids by Hamada, K, Umemoto, A, Kajikawa, A, Seraj, M J, Monden, Y

“…The in vitro experiment was carried out following 32P-postlabeling analysis to determine the DNA-reactive bile acids present in the human body. The…”
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DNA adducts detected in human gastric mucosa by Momen, Mohammed Abdul, Monden, Yasumasa, Hamada, Kunimi, Komaki, Kansei, Kondo, Kazuya, Umemoto, Atsushi

“…Human gastrointestinal neoplasms are mostly developed from the mucosa, not from the adjacent muscle layer. DNA adducts in the mucosa and adjacent muscle layer…”
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