Search Results - "Umehara, Hayato"
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Satiety factor oleoylethanolamide recruits the brain histaminergic system to inhibit food intake
Published in Proceedings of the National Academy of Sciences - PNAS (05-08-2014)“…Key factors driving eating behavior are hunger and satiety, which are controlled by a complex interplay of central neurotransmitter systems and peripheral…”
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Identification of a histaminergic circuit in the caudal hypothalamus: An evidence for functional heterogeneity of histaminergic neurons
Published in Neurochemistry international (01-11-2012)“…► The caudal ARC was activated through H1R by food-deprivation under scheduled feeding. ► E3 subgroup of the TMN was activated by food-deprivation under…”
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Deprivation of anticipated food under scheduled feeding induces c-Fos expression in the caudal part of the arcuate nucleus of hypothalamus through histamine H1 receptors in rats: Potential involvement of E3 subgroup of histaminergic neurons in tuberomammillary nucleus
Published in Brain research (28-04-2011)“…Abstract It is well established that histaminergic neurons densely innervate the anterior hypothalamus and regulate several functions through histamine H1…”
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Suplatast Tosilate Inhibits Histamine Signaling by Direct and Indirect Down-Regulation of Histamine H1 Receptor Gene Expression through Suppression of Histidine Decarboxylase and IL-4 Gene Transcriptions
Published in The Journal of immunology (1950) (01-08-2009)“…Allergic rhinitis (AR) is an inflammatory disorder typified by symptoms such as sneezing, congestion, and rhinorrhea. Histamine plays important roles in…”
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Kujin Suppresses Histamine Signaling at the Transcriptional Level in Toluene 2,4-Diisocyanate–Sensitized Rats
Published in Journal of Pharmacological Sciences (2009)“…Kujin, the dried root of Sophorae flavescensis, has been used in Chinese folklore medicine against allergy. Evaluation of its anti-allergic potential as well…”
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Sho-seiryu-to Suppresses Histamine Signaling at the Transcriptional Level in TDI-Sensitized Nasal Allergy Model Rats
Published in Allergology international (2009)“…The therapeutic use of Kampo medicine, Sho-seiryu-to (SST) in allergic disorders is well known. As histamine plays a central role in allergic diseases, it is…”
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Repeated Pre-treatment With Antihistamines Causes Transcriptional Up-regulations of Histamine H1 Receptor and Interleukin-4 Genes in Toluene-2,4-diisocyanate–Sensitized Rats
Published in Journal of Pharmacological Sciences (2008)“…Antihistamines are effective for treatment of seasonal nasal allergy. Recently, prophylactic treatment with antihistamines in patients with pollinosis was…”
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Suppression of Histamine Signaling by Probiotic Lac-B: a Possible Mechanism of Its Anti-allergic Effect
Published in Journal of Pharmacological Sciences (2008)“…It has been shown that probiotic bacteria are effective for the treatment of allergic diseases. As histamine plays a central role in allergic diseases, it is…”
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Evaluation of Efficacy and Sedative Profiles of H1 Antihistamines by Large-Scale Surveillance Using the Visual Analogue Scale (VAS)
Published in Allergology international (2008)“…H1 antihistamines are widely used as therapeutics for allergic diseases. Sedation is a well-known side effect of H1 antihistamines and sometimes it is…”
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Effects of hypergravity on histamine H1 receptor mRNA expression in hypothalamus and brainstem of rats: implications for development of motion sickness
Published in Acta oto-laryngologica (2009)“…Conclusion: The study findings suggest that histamine was released from the axon terminals in the hypothalamus and brainstem and the released histamine…”
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Down-regulation of histamine H1 receptors by β2-adrenoceptor-mediated inhibition of H1 receptor gene transcription
Published in Journal of pharmacy and pharmacology (01-06-2008)“…Histamine H1 receptor (H1R) levels vary under various pathological conditions, and these changes may be responsible for some pathogenesis such as in allergic…”
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The hypophagic factor oleoylethanolamide differentially increases c-fos expression in appetite regulating centres in the brain of wild type and histamine deficient mice
Published in Pharmacological research (01-11-2016)“…[Display omitted] Histaminergic neurons in the hypothalamic tuberomamillary nucleus (TMN) establish connections with virtually all brain areas. Recent evidence…”
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Evaluation of Efficacy and Sedative Profiles of H1 Antihistamines by Large-Scale Surveillance Using the Visual Analogue Scale (VAS)
Published in Allergology International (2008)“…Background: H1 antihistamines are widely used as therapeutics for allergic diseases. Sedation is a well-known side effect of H1 antihistamines and sometimes it…”
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14
Deprivation of anticipated food under scheduled feeding induces c-Fos expression in the caudal part of the arcuate nucleus of hypothalamus through histamine H 1 receptors in rats: Potential involvement of E3 subgroup of histaminergic neurons in tuberomammillary nucleus
Published in Brain research (28-04-2011)“…It is well established that histaminergic neurons densely innervate the anterior hypothalamus and regulate several functions through histamine H 1 receptor…”
Get full text
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Down-regulation of histamine H1 receptors by b2-adrenoceptor-mediated inhibition of H1 receptor gene transcription
Published in Journal of pharmacy and pharmacology (01-06-2008)“…Histamine H1 receptor (H1R) levels vary under various pathological conditions, and these changes may be responsible for some pathogenesis such as in allergic…”
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Journal Article -
18
Down-regulation of histamine H1 receptors by beta2-adrenoceptor-mediated inhibition of H1 receptor gene transcription
Published in Journal of pharmacy and pharmacology (01-06-2008)“…Histamine H1 receptor (H1R) levels vary under various pathological conditions, and these changes may be responsible for some pathogenesis such as in allergic…”
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Journal Article -
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Evaluation of efficacy and sedative profiles of H(1) antihistamines by large-scale surveillance using the visual analogue scale (VAS)
Published in Allergology international (01-09-2008)“…H(1) antihistamines are widely used as therapeutics for allergic diseases. Sedation is a well-known side effect of H(1) antihistamines and sometimes it is…”
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Repeated pre-treatment with antihistamines suppresses [corrected] transcriptional up-regulations of histamine H(1) receptor and interleukin-4 genes in toluene-2,4-diisocyanate-sensitized rats
Published in Journal of pharmacological sciences (01-12-2008)“…Antihistamines are effective for treatment of seasonal nasal allergy. Recently, prophylactic treatment with antihistamines in patients with pollinosis was…”
Get full text
Journal Article