Search Results - "Umar, Mohd. Saad"
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Selective Targeting of 4SO4-N-Acetyl-Galactosamine Functionalized Mycobacterium tuberculosis Protein Loaded Chitosan Nanoparticle to Macrophages: Correlation With Activation of Immune System
Published in Frontiers in microbiology (20-11-2018)“…In the present study, we investigated potential of chitosan-based nanoparticles (CNPs) to deliver loaded therapeutic molecules to pathogen harboring…”
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Immunotherapy With 5, 15-DPP Mediates Macrophage M1 Polarization and Modulates Subsequent Mycobacterium tuberculosis Infectivity in rBCG30 Immunized Mice
Published in Frontiers in immunology (29-10-2021)“…Tuberculosis (TB) is a significant and continuing problem worldwide, with a death toll of around 1.5 million human lives annually. BCG, the only vaccine…”
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Bioactive Gum Arabic/κ-Carrageenan-Incorporated Nano-Hydroxyapatite Nanocomposites and Their Relative Biological Functionalities in Bone Tissue Engineering
Published in ACS omega (26-05-2020)“…The present frontiers of bone tissue engineering are being pushed by novel biomaterials that exhibit phenomenal biocompatibility and adequate mechanical…”
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Combinatorial approach to fabricate silica doped polyvinyl alcohol/hydroxyapatite/carrageenan nanocomposite for bone regeneration applications
Published in Polymers for advanced technologies (01-07-2023)“…Bone tissue engineering is a dominating approach for the fabrication of nanocomposite bone implants with superior biocompatibility and low toxicity to the…”
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Exosome-encapsulated ncRNAs: Emerging yin and yang of tumor hallmarks
Published in Frontiers in genetics (20-10-2022)“…Tumorigenesis is a multifaceted process, where multiple physiological traits serving as cancer’s distinctive characteristics are acquired. “Hallmarks of…”
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Bio-mediated synthesis of 5-FU based nanoparticles employing orange fruit juice: a novel drug delivery system to treat skin fibrosarcoma in model animals
Published in Scientific reports (23-08-2019)“…Nano-sized drug delivery systems (NDDS) have been widely exploited to achieve targeted delivery of pharmaco-materials. Traditional pharmaceutical approaches,…”
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Amyloid form of ovalbumin evokes native antigen-specific immune response in the host: prospective immuno-prophylactic potential
Published in The Journal of biological chemistry (13-02-2015)“…Amyloids are highly organized protein aggregates that arise from inappropriately folded versions of proteins or polypeptides under both physiological as well…”
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Leishmania-Specific Promiscuous Membrane Protein Tubulin Folding Cofactor D Divulges Th1/Th2 Polarization in the Host via ERK-1/2 and p38 MAPK Signaling Cascade
Published in Frontiers in immunology (02-06-2020)“…Visceral leishmaniasis (VL)-related mortality and morbidity imposes a great deal of health concern across the globe. The existing anti-leishmanial drug regimen…”
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Fabrication of Microbicidal Silver Nanoparticles: Green Synthesis and Implications in the Containment of Bacterial Biofilm on Orthodontal Appliances
Published in Frontiers in nanotechnology (07-04-2022)“…Among various metal-based nanoparticles, silver nanoparticles (AgNPs) manifest superior inhibitory effects against several microorganisms. In fact, the…”
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Synthesis of steroidal dihydropyrazole derivatives using green ZnO NPs and evaluation of their anticancer and antioxidant activity
Published in Steroids (01-12-2022)“…[Display omitted] •ZnO NPs were synthesized by a green method using Azadirachta indica leaf extract.•Steroidal dihydropyrazole derivatives are synthesized via…”
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Efficacy of IL10/STAT3 directed small molecule immunotherapy in augmenting the potential of rBCG30 vaccine against murine pulmonary tuberculosis
Published in Molecular immunology (01-10-2022)“…Several recent studies have contributed to our understanding of the need for host directed immunotherapeutic strategies against Mycobacterium tuberculosis…”
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A small molecule based immunotherapy targeting IL-10/STAT3 praxis to augment the potential of rBCG30 vaccine against experimental tuberculosis
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Several recent studies have contributed to our understanding of the need for host directed immunotherapeutic strategies against Mycobacterium…”
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Corrigendum: Selective Targeting of 4SO 4 - N -Acetyl-Galactosamine Functionalized Mycobacterium tuberculosis Protein Loaded Chitosan Nanoparticle to Macrophages: Correlation With Activation of Immune System
Published in Frontiers in microbiology (2020)“…[This corrects the article DOI: 10.3389/fmicb.2018.02469.]…”
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Hydroxyapatite/Chondroitin Sulphate Nanocomposite Infused with Black Seed Oil for Bone Tissue Applications: Physicochemical Characterizations and In Vitro Screening
Published in ChemistrySelect (Weinheim) (08-11-2024)“…Morbidities associated with natural bone have highlighted the need of advanced bioactive implants for the replacement of damaged bone. Known for their…”
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Hydroxyapatite Nanoparticles Fortified Xanthan Gum-Chitosan Based Polyelectrolyte Complex Scaffolds for Supporting the Osteo-Friendly Environment
Published in ACS applied bio materials (19-10-2020)“…Nanoparticle-reinforced polymer-based scaffolding matrices as artificial bone-implant materials are potential suitors for bone regenerative medicine as they…”
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Selective Targeting of 4SO 4 - N -Acetyl-Galactosamine Functionalized Mycobacterium tuberculosis Protein Loaded Chitosan Nanoparticle to Macrophages: Correlation With Activation of Immune System
Published in Frontiers in microbiology (2018)“…In the present study, we investigated potential of chitosan-based nanoparticles (CNPs) to deliver loaded therapeutic molecules to pathogen harboring…”
Get full text
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A Potent Inhibitor of IL-10/STAT3 Axis Signaling Modulates Anti-Inflammatory Responses and Boosts Anti-Tuberculosis Immunity in rBCG30 Immunized Mice
Published in International journal of mycobacteriology (01-01-2021)“…Aims and Objectives: In the present study we tried to improve anti-TB immunity offered by 2 nd generation rBCG30 vaccine. We attempted to bolster rBCG30…”
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