Search Results - "Umano, Takaaki"

In vivo mutagenicity assessment of styrene in MutaMouse liver and lung by Murata, Yasumasa, Natsume, Masakatsu, Iso, Takako, Shigeta, Yoshiyuki, Hirose, Nozomu, Umano, Takaaki, Horibata, Katsuyoshi, Sugiyama, Kei-Ichi, Masumura, Kenichi, Hirose, Akihiko, Matsumoto, Mariko

“…Styrene (CAS 100-42-5) is widely used as polystyrene and acrylonitrile-butadiene-styrene resin such as plastic, rubber, and paint. One of the primary uses of…”
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Lack of in vivo mutagenicity of carbendazim in the liver and glandular stomach of MutaMice by Iso, Takako, Suzuki, Kenichiro, Murata, Yasumasa, Hirose, Nozomu, Umano, Takaaki, Horibata, Katsuyoshi, Sugiyama, Kei-Ichi, Hirose, Akihiko, Masumura, Kenichi, Matsumoto, Mariko

“…Carbendazim (methyl 2-benzimidazolecarbamate, CASRN: 10605-21-7) exhibits spindle poisoning effects and is widely used as a fungicide. With respect to…”
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In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse by Murata, Yasumasa, Suzuki, Kenichiro, Shigeta, Yoshiyuki, Iso, Takako, Hirose, Nozomu, Umano, Takaaki, Horibata, Katsuyoshi, Sugiyama, Kei-ichi, Hirose, Akihiko, Masumura, Kenichi, Matsumoto, Mariko

“…tert-Butyl hydroperoxide (TBHP; CAS 75-91-2), a hydroperoxide, is mainly used as a polymerization initiator to produce polyethylene, polyvinyl chloride, and…”
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A TWO-GENERATION REPRODUCTIVE TOXICITY STUDY OF BUTYL BENZYL PHTHALATE IN RATS by ASO, Sunao, EHARA, Hatsune, MIYATA, Katsumi, HOSYUYAMA, Satsuki, SHIRAISHI, Keiji, UMANO, Takaaki, MINOBE, Yasusi

“…A two-generation reproductive toxicity study with extra parameters was performed for Butyl benzyl phthalate (BBP). The compound was administered orally by…”
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Derivation of subacute guidance values for chemical contaminants of drinking water quality standard in Japan by Matsumoto, Mariko, Murata, Yasumasa, Hirose, Nozomu, Shigeta, Yoshiyuki, Iso, Takako, Umano, Takaaki, Hirose, Akihiko

“…The concentration of chemicals in drinking water may transiently and accidently exceed the Drinking Water Quality Standard (DWQS). If the level of a…”
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A TWO-GENERATION REPRODUCTIVE TOXICITY STUDY OF 4-NITROTOLUENE IN RATS by ASO, Sunao, MIYATA, Katsumi, EHARA, Hatsune, HOSYUYAMA, Satsuki, SHIRAISHI, Keiji, UMANO, Takaaki, MINOBE, Yasusi

“…4-nitrotoluene (4-NT) was administered orally at doses of 0, 40, 80, or 160 mg/kg/day by gavage to 24 Crj:CD®(SD)IGS rats of each sex per group over two…”
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Endocrine-mediated effects of 4,4’-(hexafluoroisopropylidene)diphenol in SD rats, based on a subacute oral toxicity study by Umano, Takaaki, Tanaka, Ryota, Yamasaki, Kanji

“…The purpose of this study was to investigate the endocrine-mediated effects of 4,4’-(hexafluoroisopropylidene)diphenol according to OECD test guideline no…”
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Lack of in vivo mutagenicity of carbendazim in the liver and glandular stomach of MutaMice by Takako Iso, Kenichiro Suzuki, Yasumasa Murata, Nozomu Hirose, Takaaki Umano, Katsuyoshi Horibata, Kei-ichi Sugiyama, Akihiko Hirose, Kenichi Masumura, Mariko Matsumoto

“…[Abstract] [Background] Carbendazim (methyl 2-benzimidazolecarbamate, CASRN: 10605-21-7) exhibits spindle poisoning effects and is widely used as a fungicide…”
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In vivo mutagenicity assessment of styrene in MutaMouse liver and lung by Yasumasa Murata, Masakatsu Natsume, Takako Iso, Yoshiyuki Shigeta, Nozomu Hirose, Takaaki Umano, Katsuyoshi Horibata, Kei-ichi Sugiyama, Kenichi Masumura, Akihiko Hirose, Mariko Matsumoto

“…[Abstract] [Background] Styrene (CAS 100-42-5) is widely used as polystyrene and acrylonitrile-butadiene-styrene resin such as plastic, rubber, and paint. One…”
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In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse by Yasumasa Murata, Kenichiro Suzuki, Yoshiyuki Shigeta, Takako Iso, Nozomu Hirose, Takaaki Umano, Katsuyoshi Horibata, Kei-ichi Sugiyama, Akihiko Hirose, Kenichi Masumura, Mariko Matsumoto

“…[Abstract][Background] tert-Butyl hydroperoxide (TBHP; CAS 75-91-2), a hydroperoxide, is mainly used as a polymerization initiator to produce polyethylene,…”
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Neurobehavioral toxicity of acrylamide and IDPN (3,3'-iminodipropionitrile) in rats by 28-day oral administration--problems encountered in collaborative study and a commentary on conducting neurobehavioral testing by Okazaki, Shuzo, Takashima, Hiromasa, Yamaguchi, Makiko, Hamamura, Masao, Yamashita, Kotaro, Okada, Masaaki, Sunaga, Masao, Tanaka, Ryota, Sato, Shinichi, Umano, Takaaki, Tsuji, Ryozo, Yosioka, Takafumi, Fujii, Tomoko

“…In order to clarify technical problems in evaluating neurotoxicity of chemicals and to solve them, a collaborative study with a common protocol was conducted…”
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Enhanced OECD TG 407 in detection of endocrine-mediated effects of 4,4′-(octahydro-4,7-methano-5H-inden-5-ylidene)bisphenol by Umano, Takaaki, Miyata, Katsumi, Minobe, Yasushi, Yamasaki, Kanji

“…The purpose of this study was to investigate whether the estrogenic effects were detected in the enhanced TG 407 if the estrogenic property was not so strong…”
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Uterotrophic assay, Hershberger assay, and subacute oral toxicity study of 3-amino-1,2,4-triazole based on the Organization for Economic Co-operation and Development draft protocols by Umano, Takaaki, Shiraishi, Keiji, Minobe, Yasushi, Yamasaki, Kanji

“…We performed a uterotrophic assay, the Hershberger assay, and the 28-day repeated-dose toxicity study (enhanced OECD test guideline no. 407) of…”
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Subacute oral toxicity study of di(2-ethylhexyl)adipate based on the draft protocol for the Enhanced OECD Test Guideline no. 407 by MIYATA, Katsumi, SHIRAISHI, Keiji, HOUSHUYAMA, Satsuki, IMATANAKA, Nobuya, UMANO, Takaaki, MINOBE, Yasushi, YAMASAKI, Kanji

“…We performed a 28-day repeated-dose toxicity study of di(2-ethylhexyl)adipate (DEHA) based on the draft protocol of the "Enhanced OECD Test Guideline 407" to…”
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Subacute oral toxicity study of diethylphthalate based on the draft protocol for enhanced OECD test guideline no. 407 by SHIRAISHI, Keiji, MIYATA, Katusi, HOUSHUYAMA, Satsuki, IMATANAKA, Nobuya, UMANO, Takaaki, MINOBE, Yasushi, YAMASAKI, Kanji

“…We performed a 28-day repeated-dose toxicity study of diethylphthalate based on the draft protocol of the "Enhanced OECD Test Guideline 407" to investigate…”
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TazobactamとPiperacillinの配合剤およびTazobactamの単回投与毒性試験 by 林, 泰司, 矢田, 英昭, 穴井, 真紀子, 馬野, 高昭, 河津, 孝二, 穴井, 俊二, 梶原, 利彦, 山崎, 寛治

“…TAZ/PIPCおよびTAZのマウス, ラットおよびイヌにおける単回投与毒性を検討し, 以下の結果を得た。1. マウスおよびラッ卜ではTAZ/PIPC, TAZともすべての投与経路において軟便がみられ, 皮下,…”
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SINGLE-DOSE TOXICITY STUDIES OF TAZOBACTAM/PIPERACILLIN AND TAZOBACTAM by HAYASHI, Taiji, YADA, Hideaki, ANAI, Makiko, UMANO, Takaaki, KAWAZU, Kouji, ANAI, Shunji, KAZIWARA, Toshihiko, YAMASAKI, Kanji

“…Tazobactam (TAZ) is a newly developed β-lactamase inhibitor. Tazobactam/Piperacillin (TAZ/PIPC) is a formulation consisting of TAZ and PIPC in a ratio of 1:4…”
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