Search Results - "Ulyanova, Alexandra V."

Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue by Lovatt, Ditte, Ruble, Brittani K, Lee, Jaehee, Dueck, Hannah, Kim, Tae Kyung, Fisher, Stephen, Francis, Chantal, Spaethling, Jennifer M, Wolf, John A, Grady, M Sean, Ulyanova, Alexandra V, Yeldell, Sean B, Griepenburg, Julianne C, Buckley, Peter T, Kim, Junhyong, Sul, Jai-Yoon, Dmochowski, Ivan J, Eberwine, James

“…A noninvasive method is reported for the isolation and profiling of the transcriptome from a single cell in the context of intact tissue. Transcriptome…”
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Voltage-dependent inward currents in smooth muscle cells of skeletal muscle arterioles by Ulyanova, Alexandra V, Shirokov, Roman E

“…Voltage-dependent inward currents responsible for the depolarizing phase of action potentials were characterized in smooth muscle cells of 4th order arterioles…”
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CHEX-seq detects single-cell genomic single-stranded DNA with catalytical potential by Lu, Youtao, Lee, Jaehee, Li, Jifen, Allu, Srinivasa Rao, Wang, Jinhui, Kim, HyunBum, Bullaughey, Kevin L., Fisher, Stephen A., Nordgren, C. Erik, Rosario, Jean G., Anderson, Stewart A., Ulyanova, Alexandra V., Brem, Steven, Chen, H. Isaac, Wolf, John A., Grady, M. Sean, Vinogradov, Sergei A., Kim, Junhyong, Eberwine, James

“…Genomic DNA (gDNA) undergoes structural interconversion between single- and double-stranded states during transcription, DNA repair and replication, which is…”
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Pervasive within-Mitochondrion Single-Nucleotide Variant Heteroplasmy as Revealed by Single-Mitochondrion Sequencing by Morris, Jacqueline, Na, Young-Ji, Zhu, Hua, Lee, Jae-Hee, Giang, Hoa, Ulyanova, Alexandra V., Baltuch, Gordon H., Brem, Steven, Chen, H. Isaac, Kung, David K., Lucas, Timothy H., O’Rourke, Donald M., Wolf, John A., Grady, M. Sean, Sul, Jai-Yoon, Kim, Junhyong, Eberwine, James

“…A number of mitochondrial diseases arise from single-nucleotide variant (SNV) accumulation in multiple mitochondria. Here, we present a method for…”
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Primary Cell Culture of Live Neurosurgically Resected Aged Adult Human Brain Cells and Single Cell Transcriptomics by Spaethling, Jennifer M., Na, Young-Ji, Lee, Jaehee, Ulyanova, Alexandra V., Baltuch, Gordon H., Bell, Thomas J., Brem, Steven, Chen, H. Isaac, Dueck, Hannah, Fisher, Stephen A., Garcia, Marcela P., Khaladkar, Mugdha, Kung, David K., Lucas, Timothy H., O’Rourke, Donald M., Stefanik, Derek, Wang, Jinhui, Wolf, John A., Bartfai, Tamas, Grady, M. Sean, Sul, Jai-Yoon, Kim, Junhyong, Eberwine, James H.

“…Investigation of human CNS disease and drug effects has been hampered by the lack of a system that enables single-cell analysis of live adult patient brain…”
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Multichannel Silicon Probes for Awake Hippocampal Recordings in Large Animals by Ulyanova, Alexandra V, Cottone, Carlo, Adam, Christopher D, Gagnon, Kimberly G, Cullen, D Kacy, Holtzman, Tahl, Jamieson, Brian G, Koch, Paul F, Chen, H Isaac, Johnson, Victoria E, Wolf, John A

“…Decoding laminar information across deep brain structures and cortical regions is necessary in order to understand the neuronal ensembles that represent…”
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Hippocampal interneuronal dysfunction and hyperexcitability in a porcine model of concussion by Ulyanova, Alexandra V., Adam, Christopher D., Cottone, Carlo, Maheshwari, Nikhil, Grovola, Michael R., Fruchet, Oceane E., Alamar, Jami, Koch, Paul F., Johnson, Victoria E., Cullen, D. Kacy, Wolf, John A.

“…Cognitive impairment is a common symptom following mild traumatic brain injury (mTBI or concussion) and can persist for years in some individuals. Hippocampal…”
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Single cell phototransfection of mRNAs encoding SARS-CoV2 spike and nucleocapsid into human astrocytes results in RNA dependent translation interference by Kim, Hyun-Bum, Brosseau, Quentin, Radzio, Julia, Wang, Jinhui, Muramatsu, Hiromi, Kuang, Da, Grady, M. Sean, Chen, H. Isaac, Wolf, John A., Ulyanova, Alexandra V., Bartfai, Tamas, Kim, Junhyong, Pardi, Norbert, Sul, Jai-Yoon, Arratia, Paulo, Eberwine, James

“…Multi-RNA co-transfection is starting to be employed to stimulate immune responses to SARS-CoV-2 viral infection. While there are good reasons to utilize such…”
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Traumatic Brain Injury Preserves Firing Rates But Disrupts Laminar Oscillatory Coupling and Neuronal Entrainment in Hippocampal CA1 by Koch, Paul F, Cottone, Carlo, Adam, Christopher D, Ulyanova, Alexandra V, Russo, Robin J, Weber, Maura T, Arena, John D, Johnson, Victoria E, Wolf, John A

“…While hippocampal-dependent learning and memory are particularly vulnerable to traumatic brain injury (TBI), the functional status of individual hippocampal…”
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Electrophysiological Signature Reveals Laminar Structure of the Porcine Hippocampus by Ulyanova, Alexandra V, Koch, Paul F, Cottone, Carlo, Grovola, Michael R, Adam, Christopher D, Browne, Kevin D, Weber, Maura T, Russo, Robin J, Gagnon, Kimberly G, Smith, Douglas H, Isaac Chen, H, Johnson, Victoria E, Kacy Cullen, D, Wolf, John A

“…The hippocampus is integral to working and episodic memory and is a central region of interest in diseases affecting these processes. Pig models are widely…”
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Automatic High-Frequency Oscillations Detection Using Time-Frequency Analysis by Mirzakhalili, Ehsan, Adam, Christopher D., Ulyanova, Alexandra V., Johnson, Victoria E., Wolf, John A.

“…The role of high-frequency oscillations (HFO) has been established in a multitude of the brain functions such as retrieval and consolidation of memory…”
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Transcriptome In Vivo Analysis (TIVA) of spatially defined single cells in intact live mouse and human brain tissue by Lovatt, Ditte, Ruble, Brittani K., Lee, Jaehee, Dueck, Hannah, Kim, Tae Kyung, Fisher, Stephen, Francis, Chantal, Spaethling, Jennifer M., Wolf, John A., Grady, M. Sean, Ulyanova, Alexandra V., Yeldell, Sean B., Griepenburg, Julianne C., Buckley, Peter T., Kim, Junhyong, Sul, Jai-Yoon, Dmochowski, Ivan J., Eberwine, James

“…Transcriptome profiling is an indispensable tool in advancing the understanding of single cell biology, but depends upon methods capable of isolating mRNA at…”
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Subcellular Genomics: Pervasive within-mitochondrion SNV heteroplasmy revealed by single mitochondrion sequencing by Morris, Jacqueline, Na, Young-Ji, Zhu, Hua, Lee, Jae-Hee, Giang, Hoa, Ulyanova, Alexandra V., Baltuch, Gordon H., Brem, Steven, Chen, H. Isaac, Kung, David K., Lucas, Timothy H., O’Rourke, Donald M., Wolf, John A., Grady, M. Sean, Sul, Jai-Yoon, Kim, Junhyong, Eberwine, James

“…A number of mitochondrial diseases arise from Single Nucleotide Variant (SNV) accumulation in multiple mitochondria. Here we present a method for…”
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