Search Results - "Ulusoy, Nuray"

Synthesis, characterization, molecular docking and in vitro anti-cancer activity studies of new and highly selective 1,2,3-triazole substituted 4-hydroxybenzohyrdazide derivatives by Şenol, Halil, Ağgül, Ahmet Gökhan, Atasoy, Sezen, Güzeldemirci, Nuray Ulusoy

“…•The new HER2 inhibitors was synthesized with a thiazolidine-4-one structure.•Compound 7g is the most potent against MCF7 cells with IC50 values 4.38 µM.•The…”
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Synthesis and antimicrobial activity evaluation of new 1,2,4-triazoles and 1,3,4-thiadiazoles bearing imidazo[2,1- b]thiazole moiety by Güzeldemirci, Nuray Ulusoy, Küçükbasmacı, Ömer

“…A series of 4-alkyl/aryl-2,4-dihydro-5-((6-(4-bromophenyl)imidazo[2,1- b]thiazol-3-yl)methyl)-3 H-1,2,4-triazole-3-thiones ( 3a– i) and…”
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Design, synthesis, characterization and antimicrobial evaluation of some novel hydrazinecarbothioamide, 4‐thiazolidinone and 1,2,4‐triazole‐3‐thione derivatives by Dincel, Efe Doğukan, Ulusoy‐Güzeldemirci, Nuray, Şatana, Dilek, Küçükbasmacı, Ömer

“…A series of novel hydrazinecarbothioamide (5a,c,f), 4‐thiazolidinone (6a‐e), and 1,2,4‐triazole‐3‐thione (7a‐d) were designed and synthesized. The structural…”
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Synthesis and primary cytotoxicity evaluation of new imidazo[2,1- b]thiazole derivatives by GÜRSOY, Elif, GUZELDEMIRCI, Nuray Ulusoy

“…A series of arylidenehydrazides ( 3a– 3i) were synthesized from [6-(4-bromophenyl)imidazo[2,1- b]thiazol-3-yl]acetic acid hydrazide. The structures of new…”
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Synthesis of Novel Carboxamide Derivatives: Insecticidal Activity, Acetylcholinesterase Activity and In Silico Calculations by Mermer, Arif, Yorulmaz, Sibel, Dincel, Efe Doğukan, Şirin, Yakup, Güzeldemirci, Nuray Ulusoy

“…•Novel synthesized carboxamide derivatives•Insecticidal activity against Myzus percisace, Leptinotarsa decemlineata, and Trialeurodes vaporariorum•In vitro and…”
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Novel imidazo[2,1‐b]thiazole‐based anticancer agents as potential focal adhesion kinase inhibitors: Synthesis, in silico and in vitro evaluation by Başoğlu, Faika, Ulusoy‐Güzeldemirci, Nuray, Akalın‐Çiftçi, Gülşen, Çetinkaya, Serap, Ece, Abdulilah

“…The purpose of this study was to synthesize imidazo[2,1‐b]thiazole derivatives, characterize them with spectroscopical techniques and investigate for cytotoxic…”
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Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease by Dincel, Efe Doğukan, Başoğlu‐Ünal, Faika, Kuran, Ebru Didem, Kayra, Tülay, Aydın, Nurcan, Kanber, Esmanur, Gülçin, İlhami, Ulusoy‐Güzeldemirci, Nuray

“…In this project, non‐sulfonamide bistrifluoromethyl‐derived hydrazide‐hydrazones were synthesized as multi‐target‐directed ligands to treat Alzheimer's disease…”
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Synthesis and biological evaluation of new imidazo[2,1-b]thiazole derivatives as anticancer agents by Karaman, Berin, Ulusoy Güzeldemirci, Nuray

“…A series of arylidenehydrazide compounds ( 3a – 3j ) were synthesized from [6-(4-chlorophenyl)imidazo[2,1- b ]thiazol-3-yl]acetic acid hydrazide. The newly…”
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Antibacterial, Antitubercular and Antiviral Activity Evaluations of Some Arylidenehydrazide Derivatives Bearing Imidazo[2,1- b ]thiazole Moiety by Ulusoy Güzeldemirci, Nuray, Karaman, Berin, Küçükbasmaci, Ömer

“…The aim of this study was to determine the probable antibacterial, antitubercular, and antiviral activities of some -arylidene-(6-(4-chlorophenyl)imidazo[2,1-…”
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Design and synthesis of novel Imidazo[2,1-b]thiazole derivatives as potent antiviral and antimycobacterial agents by Gürsoy, Elif, Dincel, Efe Doğukan, Naesens, Lieve, Ulusoy Güzeldemirci, Nuray

“…[Display omitted] •Development of novel antimycobacterial drugs is an obligation.•Spirothiazolidinone moiety is potent for antitubercular activity.•Ring…”
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Synthesis, characterization, and antimicrobial evaluation of some new hydrazinecarbothioamide, 1,2,4-triazole and 1,3,4-thiadiazole derivatives by Güzeldemirci, Nuray Ulusoy, Satana, Dilek, Küçükbasmacı, Omer

“…In this work, we reported the synthesis and evaluation of antibacterial and antifungal activities of three new compound series obtained from…”
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Synthesis and Aldose Reductase Inhibitory Effect of Some New Hydrazinecarbothioamides and 4-Thiazolidinones Bearing an Imidazo[2,1- b ]Thiazole Moiety by Ulusoy Güzeldemirci, Nuray, Cimok, Selin, Daş-Evcimen, Net, Sarikaya, Mutlu

“…To synthesize and characterize 2-[[6-(4-bromophenyl)imidazo[2,1- ]thiazol-3-yl]acetyl]- -alkyl/arylhydrazinecarbothioamide and…”
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A newly synthesized thiosemicarbazide derivative trigger apoptosis rather than necroptosis on HEPG2 cell line by Başoğlu‐Ünal, Faika, Becer, Eda, Ensarioğlu, Hilal Kabadayı, ‐Güzeldemirci, Nuray Ulusoy, Kuran, Ebru Didem, Vatansever, H. Seda

“…Thiosemicarbazide derivatives have been the focus of scientists owing to their broad biological activities such as anticancer, antimicrobial, and…”
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Synthesis and antimicrobial evaluation of some new hydrazone derivatives of 6-(4-nitrophenyl)imidazo[2,1-b]thiazole-3-acetic acid hydrazide by Güzeldemirci,Nuray Ulusoy, Şatana,Dilek, Küçükbasmacı,Ömer

“…In this study, some novel N2-arylidene/cycloalkylidene-(6-(4-nitrophenyl)imidazo[2,1-b]thiazol-3-yl)acetic acid hydrazides (2a-d) were synthesized from…”
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Antioxidant activity of novel imidazo[2,1-b]thiazole derivatives: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction by Dincel, Efe Doğukan, Gürsoy, Elif, Yilmaz-Ozden, Tugba, Ulusoy-Güzeldemirci, Nuray

“…[Display omitted] •The development of novel antioxidant agents possesses significance.•Imidazo[2,1-b]thiazole moiety is potent for antioxidant activity.•Ring…”
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Synthesis and antimicrobial activity evaluation of new hydrazide-hydrazones derived from 1,2,4-triazole by Ulusoy Güzeldemirci,Nuray, Şatana,Dilek, Küçükbasmacı,Ömer

“…Background and Aims: The aim in this study was to synthesize new 2-[[4-(4-chlorophenyl)-5-(furan-2-yl)-4H-1,2,4-triazol- 3-yl]sulfanyl]-N’-[(substituted…”
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Synthesis and antimicrobial evaluation of new 3-alkyl/aryl-2-[((α,α-diphenyl-α-hydroxy)acetyl)hydrazono]-5-methyl-4-thiazolidinones by Güzeldemirci, Nuray Ulusoy, Ilhan, Eser, Küçükbasmaci, Ömer, Satana, Dilek

“…New 4-thiazolidinone derivatives of benzilic acid (α,α-diphenyl-α-hydroxyacetic acid) have been synthesized and evaluated for antibacterial and antifungal…”
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Novel hydrazide-hydrazone containing 1,2,4-triazole as potent inhibitors of antiapoptotic protein Bcl-xL: Synthesis, biological evaluation, and docking studies by Kuran, Ebru Didem, Uner, Burcu, Cam, Muhammet Emin, Ulusoy-Guzeldemirci, Nuray

“…This study describes the synthesis and characterization of a series of novel hydrazide-hydrazone derivatives containing a 1,2,4-triazole ring. The compounds…”
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Design, synthesis, biological evaluation, molecular docking, and dynamic simulation study of novel imidazo[2,1-b]thiazole derivatives as potent antioxidant agents by Dincel, Efe Doğukan, Hasbal-Celikok, Gozde, Yilmaz-Ozden, Tugba, Ulusoy-Güzeldemirci, Nuray

“…•Novel imidazo[2,1-b]thiazole derivatives were synthesized.•The title compounds displayed antioxidant activity.•Molecular docking studies were…”
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Design, biological evaluation, molecular docking study and in silico ADME prediction of novel imidazo[2,1-b]thiazole derivatives as a novel class of α-glucosidase inhibitors by Dincel, Efe Doğukan, Hasbal-Celikok, Gozde, Yilmaz-Ozden, Tugba, Ulusoy-Güzeldemirci, Nuray

“…•Novel imidazo[2,1-b]thiazoles were synthesized.•α-Glucosidase inhibitory activities were evaluated.•Compounds 4d-e and 5a–d displayed higher biological…”
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