Search Results - "Ultman, James S"

A patient-specific model of reactive air pollutant uptake in proximal airways of the lung: Effect of tracheal deviation by Borhan, Shirin, Motevalian, Pouria, Ultman, James S., Bascom, Rebecca, Borhan, Ali

“…•Patient-specific dosimetry highlights difference between healthy and diseased lungs.•Proximal airway deformations have a significant effect on toxicant…”
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Longitudinal distribution of chlorine absorption in human airways: comparison of nasal and oral quiet breathing by Nodelman, Vladislav, Ultman, James S

“…Biological Transport Dynamics Laboratory, Department of Chemical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802 The fraction…”
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Ozone uptake during inspiratory flow in a model of the larynx, trachea and primary bronchial bifurcation by Padaki, Amit, Ultman, James S., Borhan, Ali

“…Three-dimensional simulations of the transport and uptake of a reactive gas such as O 3 were compared between an idealized model of the larynx, trachea, and…”
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Kinetics of ozone reaction with uric acid, ascorbic acid, and glutathione at physiologically relevant conditions by Kermani, Sanaz, Ben-Jebria, Abdellaziz, Ultman, James S.

“…This study quantified the reaction kinetics of O 3 with three low molecular weight antioxidants—uric acid (UA), ascorbic acid (AH 2), and glutathione…”
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Pulmonary function responses to ozone in smokers with a limited smoking history by Bates, Melissa L., Brenza, Timothy M., Ben-Jebria, Abdellaziz, Bascom, Rebecca, Eldridge, Marlowe W., Ultman, James S.

“…In non-smokers, ozone (O3) inhalation causes decreases in forced expiratory volume (FEV1) and dead space (VD) and increases the slope of the alveolar plateau…”
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Comparison of ozone-specific (OZAC) and oxygen radical (ORAC) antioxidant capacity assays for use with nasal lavage fluid by Rutkowski, Joseph M., Santiag, Lizzie Y., Ben-Jebria, Abdellaziz, Ultman, James S.

“…► The ORAC and OZAC assays were assessed for use with aqueous biological solutions. ► There was correlation between the methods using prepared model samples. ►…”
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Three-dimensional simulations of reactive gas uptake in single airway bifurcations by Taylor, Adekemi B, Borhan, Ali, Ultman, James S

“…The pattern of lung injury induced by the inhalation of ozone (O(3)) depends on the dose delivered to different tissues in the airways. This study examined the…”
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Modeling Approaches for Estimating the Dosimetry of Inhaled Toxicants in Children by Ginsberg, Gary L., Asgharian, Bahman, Kimbell, Julia S., Ultman, James S., Jarabek, Annie M.

“…Risk assessment of inhaled toxicants has typically focused upon adults, with modeling used to extrapolate dosimetry and risks from lab animals to humans…”
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Comparison of axisymmetric and three-dimensional models for gas uptake in a single bifurcation during steady expiration by Madasu, Srinath, Ultman, James S, Borhan, Ali

“…Reactive gas uptake is predicted and compared in a single bifurcation at steady expiratory flow in terms of Sherwood number using an axisymmetric single-path…”
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Longitudinal distribution of ozone absorption in the lung: Comparison of cigarette smokers and nonsmokers by Bates, Melissa L., Brenza, Timothy M., Ben-Jebria, Abdellaziz, Bascom, Rebecca, Ultman, James S.

“…In nonsmokers, ozone (O 3) is removed primarily by the epithelial lining fluid (ELF) of the conducting airways. We hypothesized that cigarette smokers, whose…”
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An axisymmetric single-path model for gas transport in the conducting airways by Madasu, Srinath, Borhan, All, Ultman, James S

“…In conventional one-dimensional single-path models, radially averaged concentration is calculated as a function of time and longitudinal position in the lungs,…”
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Changes in the carbon dioxide expirogram in response to ozone exposure by Taylor, Adekemi B., Lee, Genea M., Nellore, Kavitha, Ben-Jebria, Abdellaziz, Ultman, James S.

“…The objectives of this study were to quantify pulmonary responses to ozone (O 3) exposure by parameters computed from the carbon dioxide expirogram and to…”
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Application of a Hybrid Computational Fluid Dynamics and Physiologically Based Inhalation Model for Interspecies Dosimetry Extrapolation of Acidic Vapors in the Upper Airways by Frederick, Clay B., Bush, Michele L., Lomax, Larry G., Black, Kurt A., Finch, Lavorgie, Kimbell, Julia S., Morgan, Kevin T., Subramaniam, Ravi P., Morris, John B., Ultman, James S.

“…This study provides a scientific basis for interspecies extrapolation of nasal olfactory irritants from rodents to humans. By using a series of short-termin…”
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Longitudinal distribution of chlorine absorption in human airways: a comparison to ozone absorption by Nodelman, Vladislav, Ultman, James S

“…Biomolecular Transport Dynamics Laboratory, Department of Chemical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802 The bolus…”
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Uptake distribution of ozone in human lungs: intersubject variability in physiologic response by Ultman, James S, Ben-Jebria, Abdellaziz, Arnold, Steven F

“…The primary hypothesis of this study was that intersubject variation in uptake of inhaled ozone causes corresponding variation in the resulting physiologic…”
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Uptake of Ozone in Human Lungs and Its Relationship to Local Physiological Response by Reeser, Wade H., Lee, Genea M., Taylor, Adekemi, Wang, Lan, Arnold, Steve F., Ultman, James S., Ben-Jebria, Abdellaziz

“…To investigate whether intersubject variations in the dose of inhaled ozone (O3) cause corresponding variations in the physiological response, 28 female and 32…”
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Longitudinal Distribution of Ozone and Chlorine in the Human Respiratory Tract: Simulation of Nasal and Oral Breathing with the Single-Path Diffusion Model by Bush, Michele L., Zhang, Wei, Ben-Jebria, Abdellaziz, Ultman, James S.

“…In the single-path model of the respiratory system, gas transport occurs within a conduit of progressively increasing cross-sectional and surface areas by a…”
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Ozone absorption in the human nose during unidirectional airflow by Santiago, Lizzie Y, Hann, Matthew C, Ben-Jebria, Abdellaziz, Ultman, James S

“…1  Department of Chemical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802; and 2  Institut National de la Santé et de la…”
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Enhancement of O2 and CO2 transfer through microporous hollow fibers by pressure cycling by NODELMAN, V, BASKARAN, H, ULTMAN, J. S

“…An intravascular gas exchange device for the treatment of respiratory failure consisted of a multitude of blind-ended hollow fibers glued in a pine-needle…”
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Ozone uptake in the intact human respiratory tract: relationship between inhaled dose and actual dose by Rigas, Marc L, Catlin, Sandra N, Ben-Jebria, Abdellaziz, Ultman, James S

“…1  National Exposure Research Laboratory, U.S. EPA, Las Vegas 89193-3478; 2  Department of Mathematical Sciences, University of Nevada Las Vegas, Las Vegas,…”
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