Search Results - "Ulrike Heberlein"

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    Preferential Ethanol Consumption in Drosophila Models Features of Addiction by Devineni, Anita V., Heberlein, Ulrike

    Published in Current biology (29-12-2009)
    “…Alcohol addiction is a common affliction with a strong genetic component [1]. Although mammalian studies have provided significant insight into the molecular…”
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    Competing dopamine neurons drive oviposition choice for ethanol in Drosophila by Azanchi, Reza, Kaun, Karla R., Heberlein, Ulrike

    “…The neural circuits that mediate behavioral choice evaluate and integrate information from the environment with internal demands and then initiate a behavioral…”
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    A Neural Circuit Encoding the Experience of Copulation in Female Drosophila by Shao, Lisha, Chung, Phuong, Wong, Allan, Siwanowicz, Igor, Kent, Clement F., Long, Xi, Heberlein, Ulrike

    Published in Neuron (Cambridge, Mass.) (05-06-2019)
    “…Female behavior changes profoundly after mating. In Drosophila, the mechanisms underlying the long-term changes led by seminal products have been extensively…”
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    Sensory Neurons in the Drosophila Genital Tract Regulate Female Reproductive Behavior by Häsemeyer, Martin, Yapici, Nilay, Heberlein, Ulrike, Dickson, Barry J.

    Published in Neuron (Cambridge, Mass.) (26-02-2009)
    “…Females of many animal species behave very differently before and after mating. In Drosophila melanogaster, changes in female behavior upon mating are…”
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    Tissue-specific activation of a single gustatory receptor produces opposing behavioral responses in Drosophila by Joseph, Ryan M, Heberlein, Ulrike

    Published in Genetics (Austin) (01-10-2012)
    “…Understanding sensory systems that perceive environmental inputs and neural circuits that select appropriate motor outputs is essential for studying how…”
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    Enabling cell-type-specific behavioral epigenetics in Drosophila: a modified high-yield INTACT method reveals the impact of social environment on the epigenetic landscape in dopaminergic neurons by Agrawal, Pavan, Chung, Phuong, Heberlein, Ulrike, Kent, Clement

    Published in BMC biology (10-04-2019)
    “…Epigenetic mechanisms play fundamental roles in brain function and behavior and stressors such as social isolation can alter animal behavior via epigenetic…”
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    A Subset of Serotonergic Neurons Evokes Hunger in Adult Drosophila by Albin, Stephanie D., Kaun, Karla R., Knapp, Jon-Michael, Chung, Phuong, Heberlein, Ulrike, Simpson, Julie H.

    Published in Current biology (21-09-2015)
    “…Hunger is a complex motivational state that drives multiple behaviors. The sensation of hunger is caused by an imbalance between energy intake and expenditure…”
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    Acute ethanol responses in Drosophila are sexually dimorphic by Devineni, Anita V., Heberlein, Ulrike

    “…In mammalian and insect models of ethanol intoxication, low doses of ethanol stimulate locomotor activity whereas high doses induce sedation. Sex differences…”
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    Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts by Wang, Hongyan, Somers, Gregory W, Bashirullah, Arash, Heberlein, Ulrike, Yu, Fengwei, Chia, William

    Published in Genes & development (15-12-2006)
    “…The choice of self-renewal versus differentiation is a fundamental issue in stem cell and cancer biology. Neural progenitors of the Drosophila post-embryonic…”
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    Oviposition preference for and positional avoidance of acetic acid provide a model for competing behavioral drives in Drosophila by Joseph, Ryan M, Devineni, Anita V, King, Ian F.G, Heberlein, Ulrike

    “…Selection of appropriate oviposition sites is essential for progeny survival and fitness in generalist insect species, such as Drosphila melanogaster, yet…”
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    A pair of dopamine neurons target the D1-like dopamine receptor DopR in the central complex to promote ethanol-stimulated locomotion in Drosophila by Kong, Eric C, Woo, Katherine, Li, Haiyan, Lebestky, Tim, Mayer, Nasima, Sniffen, Melissa R, Heberlein, Ulrike, Bainton, Roland J, Hirsh, Jay, Wolf, Fred W

    Published in PloS one (01-04-2010)
    “…Dopamine is a mediator of the stimulant properties of drugs of abuse, including ethanol, in mammals and in the fruit fly Drosophila. The neural substrates for…”
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    Glycogen synthase kinase-3/Shaggy mediates ethanol-induced excitotoxic cell death of Drosophila olfactory neurons by French, Rachael L, Heberlein, Ulrike

    “…It has long been known that heavy alcohol consumption leads to neuropathology and neuronal death. While the response of neurons to an ethanol insult is…”
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    An evolutionary conserved role for anaplastic lymphoma kinase in behavioral responses to ethanol by Lasek, Amy W, Lim, Jana, Kliethermes, Christopher L, Berger, Karen H, Joslyn, Geoff, Brush, Gerry, Xue, Liquan, Robertson, Margaret, Moore, Monica S, Vranizan, Karen, Morris, Stephan W, Schuckit, Marc A, White, Raymond L, Heberlein, Ulrike

    Published in PloS one (22-07-2011)
    “…Anaplastic lymphoma kinase (Alk) is a gene expressed in the nervous system that encodes a receptor tyrosine kinase commonly known for its oncogenic function in…”
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    A Drosophila model for fetal alcohol syndrome disorders: role for the insulin pathway by McClure, Kimberly D, French, Rachael L, Heberlein, Ulrike

    Published in Disease models & mechanisms (01-05-2011)
    “…Prenatal exposure to ethanol in humans results in a wide range of developmental abnormalities, including growth deficiency, developmental delay, reduced brain…”
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    GPCR Signaling Is Required for Blood-Brain Barrier Formation in Drosophila by Schwabe, Tina, Bainton, Roland J., Fetter, Richard D., Heberlein, Ulrike, Gaul, Ulrike

    Published in Cell (07-10-2005)
    “…The blood-brain barrier of Drosophila is established by surface glia, which ensheath the nerve cord and insulate it against the potassium-rich hemolymph by…”
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    Happyhour, a Ste20 Family Kinase, Implicates EGFR Signaling in Ethanol-Induced Behaviors by Corl, Ammon B., Berger, Karen H., Ophir-Shohat, Galit, Gesch, Julie, Simms, Jeffrey A., Bartlett, Selena E., Heberlein, Ulrike

    Published in Cell (29-05-2009)
    “…The consequences of alcohol use disorders (AUDs) are devastating to individuals and society, yet few treatments are currently available. To identify genes…”
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    EGFR and FGFR pathways have distinct roles in Drosophila mushroom body development and ethanol-induced behavior by King, Ian F G, Eddison, Mark, Kaun, Karla R, Heberlein, Ulrike

    Published in PloS one (31-01-2014)
    “…Epidermal Growth Factor Receptor (EGFR) signaling has a conserved role in ethanol-induced behavior in flies and mice, affecting ethanol-induced sedation in…”
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    JNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivity by Kapfhamer, David, King, Ian, Zou, Mimi E, Lim, Jana P, Heberlein, Ulrike, Wolf, Fred W

    Published in PloS one (05-12-2012)
    “…Neuronal signal transduction by the JNK MAP kinase pathway is altered by a broad array of stimuli including exposure to the widely abused drug ethanol, but the…”
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