Search Results - "Ulomsky, Eugeny N."

Synthetic approaches to 1,2,4-triazolo[5,1- c ][1,2,4]triazin-7-ones as basic heterocyclic structures of the antiviral drug Riamilovir ("Triazavirin®") active against SARS-CoV-2 (COVID-19) by Artem'ev, Grigory A, Rusinov, Vladimir L, Kopchuk, Dmitry S, Savchuk, Maria I, Santra, Sougata, Ulomsky, Eugeny N, Zyryanov, Grigory V, Majee, Adinath, Du, Weijie, Charushin, Valery N, Chupakhin, Оleg N

“…Fragments of 1,2,4-triazolo[5,1- ][1,2,4]triazin-7-one are found in many compounds with various types of biological activities, including the antiviral drug…”
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A PASE Approach towards (Adamantyl‐1)‐, Alkyl‐ and (Het)Aryl‐Substituted [1, 2,4]triazolo[1, 5‐d][1, 2,4]triazines: A Sequence of Two Solvent‐Free Reactions Bearing Lower E‐Factors by Krinochkin, Alexey P., Kopchuk, Dmitry S., Giri, Kousik, Shtaitz, Yaroslav K., Starnovskaya, Ekaterina S., Khalymbadzha, Igor A., Drokin, Roman A., Ulomsky, Eugeny N., Santra, Sougata, Zyryanov, Grigory V., Rusinov, Vladimir L., Chupakhin, Oleg N.

“…A Pot, Atom, Step Economic (PASE) approach is reported towards [1, 2,4]triazolo[1, 5‐d][1, 2,4]triazines, substituted with the azole ring with pharmacophore…”
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Asymmetric induction in the reactions of 3-aryl-1,2,4-triazin-5(4 H)-ones with C-nucleophiles by Egorov, Ilya N., Zyryanov, Grigory V., Ulomsky, Eugeny N., Rusinov, Vladimir L., Chupakhin, Oleg N.

“…3-Aryl-1,2,4-triazin-5(4 H)-ones, in the presence of N-protected amino acids, react with C-nucleophiles to form…”
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Nucleophilic substitution of hydrogen in the reaction of 1,2,4-triazine-4-oxides with cyanides by Chupakhin, Oleg N., Rusinov, Vladimir L., Ulomsky, Eugeny N., Kojevnikov, Dmitry N., Neunhoeffer, Hans

“…Nucleophilic substitution of hydrogen by cyano and alkoxy groups in 1,2,4-triazine-4-oxides is reported…”
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Regiospecific cleavage of a triazole or pyrimidine ring in nitrotriazolo[1,5- a]pyrimidones by Voronin, Victor V., Ulomsky, Eugeny N., Rusinov, Vladimir L., Chupakhin, Oleg N.

“…The reaction of nitrotriazolo[1,5- a]pyrimidines 1 with primary amines leads to cleavage of the pyrimidine ring, whereas triazole ring opening takes place in…”
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Stable σ-adducts of 6-phenyl-1,2,4-triazine 4-oxides with phenols by Kojevnikov, Dmitry N., Ulomsky, Eugeny N., Rusinov, Vladimir L., Chupakhin, Oleg N., Neunhoeffer, Hans

“…The formation of some very stable adducts of phenols with 1,2,4-triazine 4-oxides, and their oxidation, has been studied…”
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