Search Results - "Ulmer, Jonathan E."
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tRNA Maturation Defects Lead to Inhibition of rRNA Processing via Synthesis of pppGpp
Published in Molecular cell (20-06-2019)“…rRNAs and tRNAs universally require processing from longer primary transcripts to become functional for translation. Here, we describe an unsuspected link…”
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2
Characterization of Glycosaminoglycan (GAG) Sulfatases from the Human Gut Symbiont Bacteroides thetaiotaomicron Reveals the First GAG-specific Bacterial Endosulfatase
Published in The Journal of biological chemistry (29-08-2014)“…Despite the importance of the microbiota in human physiology, the molecular bases that govern the interactions between these commensal bacteria and their host…”
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3
Substrate interaction dynamics and oxygen control in the active site of thymidylate synthase ThyX
Published in Biochemical journal (01-04-2014)“…Thymidylate synthase ThyX, required for DNA synthesis in many pathogenic bacteria, is considered a promising antimicrobial target. It binds FAD and three…”
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4
Functional Analysis of the Mycobacterium tuberculosis FAD-Dependent Thymidylate Synthase, ThyX, Reveals New Amino Acid Residues Contributing to an Extended ThyX Motif
Published in Journal of Bacteriology (01-03-2008)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Novel Saccharomyces cerevisiae Screen Identifies WR99210 Analogues That Inhibit Mycobacterium tuberculosis Dihydrofolate Reductase
Published in Antimicrobial Agents and Chemotherapy (01-11-2002)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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6
Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution
Published in Journal of molecular biology (07-10-2005)“…A novel flavin-dependent thymidylate synthase was identified recently as an essential gene in many archaebacteria and some pathogenic eubacteria. This enzyme,…”
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7
Negative Transcriptional Regulation Mediated by Thyroid Hormone Response Element 144 Requires Binding of the Multivalent Factor CTCF to a Novel Target DNA Sequence
Published in The Journal of biological chemistry (17-09-1999)“…DNA target sites for a “multivalent” 11-zinc-finger CCTC-binding factor (CTCF) are unusually long (∼50 base pairs) and remarkably different. In conjunction…”
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Transfer RNA Maturation Defects Lead to Inhibition of ribosomal RNA Processing via Synthesis of pppGpp
Published in Molecular cell (16-04-2019)Get full text
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9
Structure of the Mycobacterium tuberculosis Flavin Dependent Thymidylate Synthase (MtbThyX) at 2.0 Å Resolution
Published in Journal of molecular biology (20-07-2010)“…A novel flavin-dependent thymidylate synthase was identified recently as an essential gene in many archaebacteria and some pathogenic eubacteria. This enzyme,…”
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10
Structure of the Mycobacterium tuberculosis Flavin Dependent Thymidylate Synthase (MtbThyX) at 2.0 Å Resolution
Published in Journal of molecular biology (07-10-2005)“…A novel flavin-dependent thymidylate synthase was identified recently as an essential gene in many archaebacteria and some pathogenic eubacteria. This enzyme,…”
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11
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter its DNA-binding specificity
Published in Cancer research (Chicago, Ill.) (2002)“…CTCF is a widely expressed 11-zinc finger (ZF) transcription factor that is involved in different aspects of gene regulation including promoter activation or…”
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12
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity
Published in Cancer research (Chicago, Ill.) (01-01-2002)“…CTCF is a widely expressed 11-zinc finger (ZF) transcription factor that is involved in different aspects of gene regulation including promoter activation or…”
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