Search Results - "Ullah Mughal, Ehsan"
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Flavone-based hydrazones as new tyrosinase inhibitors: Synthetic imines with emerging biological potential, SAR, molecular docking and drug-likeness studies
Published in Journal of molecular structure (05-03-2022)“…Targeting tyrosinase (TYR), a key enzyme responsible for melanogenesis disorders, is a well-known approach utilized for the development of melanogenesis…”
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2
Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones
Published in Bioorganic & medicinal chemistry (15-07-2006)“…Synthesis of flavones, 4-thioflavones and 4-iminoflavones was carried out with the substitution of variable halogens, methyl, methoxy and nitro groups in the…”
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3
Scholl reaction as a powerful tool for the synthesis of nanographenes: a systematic review
Published in RSC advances (29-09-2021)“…Nanographenes, or extended polycyclic aromatic hydrocarbons, have been attracting increasing attention owing to their widespread applications in organic…”
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Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives
Published in Bioorganic chemistry (01-11-2020)“…[Display omitted] Over the course of time several drugs have been synthesized and are available in market for the treatment of inflammation. However, they were…”
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Exploring Pyrimidine-Based azo Dyes: Vibrational spectroscopic Assignments, TD-DFT Investigation, chemical Reactivity, HOMO-LUMO, ELF, LOL and NCI-RDG analysis
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-05-2024)“…[Display omitted] •DFT and spectroscopic studies of pyrimidine-based azo dyes.•Exploration of photophysical properties.•PED studies.•Charge transfer studies…”
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DDQ as a versatile and easily recyclable oxidant: a systematic review
Published in RSC advances (01-09-2021)“…2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) is the most widely used quinone with a high reduction potential, and it commonly mediates hydride transfer…”
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7
Recent advancements on the synthesis and biological significance of pipecolic acid and its derivatives
Published in Journal of molecular structure (15-11-2022)“…•Pipecolic acid (Pip) is a non-proteogenic amino acid.•Pip plays vital roles in microorganisms, plants, and animals.•It is a precursor of natural bioactive…”
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Investigation of photophysical and electronic properties of aurone derivatives: Insights from spectroscopic techniques and density functional theory calculations
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-12-2023)“…[Display omitted] •Computational (DFT) and spectroscopic studies of aurone derivatives.•Photophysical studies and quantum yield.•PED and NMR studies.•FMO,…”
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Synthesis and Investigation of the Analgesic Potential of Enantiomerically Pure Schiff Bases: A Mechanistic Approach
Published in Molecules (Basel, Switzerland) (01-08-2022)“…Schiff bases are a class of organic compounds with azomethine moiety, exhibiting a wide range of biological potentials. In this research, six chiral Schiff…”
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10
Terpyridine-metal complexes: effects of different substituents on their physico-chemical properties and density functional theory studies
Published in Royal Society open science (01-11-2020)“…A series of different substituted terpyridine (tpy)-based ligands have been synthesized by Kröhnke method. Their binding behaviour was evaluated by complexing…”
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Preliminary anticancer evaluation of new Pd(II) complexes bearing NNO donor ligands
Published in Saudi pharmaceutical journal (01-01-2024)“…[Display omitted] •Synthesis of series of novel Pd(II) complexes with NNO-donor ligands.•Subtle variations of electronics and hydrophobicity on ligand arms of…”
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12
Tris(tetraceno)triquinacenes: Synthesis and Photophysical Properties of Threefold Linearly Extended Tribenzotriquinacenes
Published in Chemistry : a European journal (18-11-2013)“…The linear extension of the rigid, C3v‐symmetrical carbon framework of tribenzotriquinacene (TBTQ) along its three wings is reported. The key step of the…”
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C3v-Symmetrical Tribenzotriquinacenes Bearing Six Benzylic Tentacle Groups at the Molecular Periphery
Published in European journal of organic chemistry (01-06-2012)“…The synthesis and characterization of several C3v‐symmetrically extended tribenzotriquinacenes (TBTQs) bearing six benzylic C1‐tentacular functional groups at…”
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14
Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies
Published in ACS omega (01-02-2022)“…In the present work, a concise library of 1,3,5-triaryl-2-pyrazolines (2a–2q) was designed and synthesized by employing a multistep strategy, and the newly…”
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15
DABCO-PEG ionic liquid catalyzed synthesis, single-crystal structure, and antioxidant activity of a flavanone derivative
Published in AIP advances (01-02-2024)“…Globally, the occurrence of skin cancers has been increasing day by day due to unprotected skin and exposure to UV radiation. This research is focused toward…”
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Synthesis, molecular docking evaluation for LOX and COX-2 inhibition and determination of in-vivo analgesic potentials of aurone derivatives
Published in Heliyon (15-05-2024)“…In the current study, seven (7) aurone derivatives (ADs) were synthesized and employed to in-vitro LOX and COX-2 assays, in-vivo models of acetic acid-induced…”
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Beneficial Effects of Natural Alkaloids from Berberis glaucocarpa as Antidiabetic Agents: An In Vitro, In Silico, and In Vivo Approach
Published in ACS omega (27-02-2024)“…Diabetes, also known as diabetes mellitus (DM), is a metabolic disorder characterized by an abnormal rise in blood sugar (glucose) levels brought on by a…”
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18
Effect of Ultrasonic Extraction Regimes on Phenolics and Antioxidant Attributes of Rice (oryza sativa L.) Cultivars
Published in Iranian journal of chemistry & chemical engineering (01-01-2018)“…Teh ultrasound-assisted magnetic stirrer was used as an effective extraction technique for teh evaluation of total phenolic contents (TPC) and antioxidant…”
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ONO-pincer Zn(II) & Cd(II) complexes: Synthesis, structural characterization, Hirshfeld surface analysis and CT-DNA interactions
Published in Journal of molecular structure (05-01-2024)“…•Successful synthesis of four new anionic/neutral ONO-pincer Zn(II) and Cd(II) complexes.•Pyridyl-Imidato Cd(II) adopted capped trigonal prism geometry…”
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20
Miscellaneous azo dyes: a comprehensive review on recent advancements in biological and industrial applications
Published in Dyes and pigments (01-03-2022)“…Azo dyes, compounds having double bond linkage between two nitrogen atoms, are widely found as a main scaffold in a massive library of organic species that…”
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