Search Results - "Ullah, Muhammad Ikram"
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Clinical and Mutation Spectrum of Autosomal Recessive Non-Syndromic Oculocutaneous Albinism (nsOCA) in Pakistan: A Review
Published in Genes (16-06-2022)“…Oculocutaneous albinism (OCA) is an autosomal recessive syndromic and non-syndromic defect with deficient or a complete lack of the melanin pigment. The…”
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AI-Driven Framework for Recognition of Guava Plant Diseases through Machine Learning from DSLR Camera Sensor Based High Resolution Imagery
Published in Sensors (Basel, Switzerland) (01-06-2021)“…Plant diseases can cause a considerable reduction in the quality and number of agricultural products. Guava, well known to be the tropics’ apple, is one…”
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Screening of Intron 1 Inversion of the Factor VIII Gene in 130 Patients with Severe Hemophilia A from a Pakistani Cohort
Published in Turkish journal of haematology (02-08-2017)“…Hemophilia A (HA) is an X-linked bleeding disorder caused by diverse mutations in the factor VIII (FVIII) gene [1]. The causative mutations of the FVIII gene…”
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CDKN2B-AS1 as a novel therapeutic target in cancer: Mechanism and clinical perspective
Published in Biochemical pharmacology (01-07-2023)“…[Display omitted] Long non-coding RNAs (lncRNA) have been identified as essential components having considerable modulatory impactson biological activities…”
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Effective Immune Functions of Micronutrients against SARS-CoV-2
Published in Nutrients (29-09-2020)“…The third coronavirus outbreak in the last two decades has caused significant damage to the world's economy and community health. The highly contagious…”
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Molecular analysis of blaSHV, blaTEM, and blaCTX-M in extended-spectrum β-lactamase producing Enterobacteriaceae recovered from fecal specimens of animals
Published in PloS one (01-01-2021)“…Colonization of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae as animal gut microbiota is a substantial global threat. This study aimed…”
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Genetic association of insulin receptor substrate-1 (IRS-1, rs1801278) gene with insulin resistant of type 2 diabetes mellitus in a Pakistani population
Published in Molecular biology reports (01-12-2019)“…Insulin resistance (IR), a pathological condition of type 2 diabetes mellitus (T2DM) is characterized by an inability of body’s tissue to respond the secreted…”
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Estimation of serum iron, serum lipids and serum liver enzymes in celiac disease patients of Saudi Arabia
Published in Pakistan journal of medical sciences (31-12-2022)“…Objectives: To evaluate the serum biochemical levels in celiac disease (CD) patients. Methods: It was a cross-sectional study carried out on 70 subjects,…”
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Gold Nanoparticles Inhibit PMA-Induced MMP-9 Expression via microRNA-204-5p Upregulation and Deactivation of NF-κBp65 in Breast Cancer Cells
Published in Biology (Basel, Switzerland) (27-05-2023)“…Breast cancer (BC) is the most common malignancy in females globally. Matrix metalloproteinase-9 (MMP-9) is crucial to the invasion, progression and spread of…”
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Associations of transcription factor 7-Like 2 (TCF7L2) gene polymorphism in patients of type 2 diabetes mellitus from Khyber Pakhtunkhwa population of Pakistan
Published in African health sciences (01-03-2021)“…Background: Type 2 diabetes mellitus (T2DM) is the most prevalent component of metabolic syndrome. Environmental factors and various complex genes like…”
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Exploring glutathione transferase and Cathepsin L-like proteinase for designing of epitopes-based vaccine against Fasciola hepatica by immunoinformatics and biophysics studies
Published in Frontiers in immunology (26-09-2024)“…Fasciolosis is a zoonotic infection and is considered a developing deserted tropical illness threatening ruminant productivity and causing financial losses…”
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Determination of serum tumor necrosis factor-alpha (TNF-α) levels in metabolic syndrome patients from Saudi population
Published in Pakistan journal of medical sciences (30-06-2021)“…To detect the relationship between serum tumor necrosis factor-alpha (TNF-α) and metabolic syndrome (MetS) components in patients of the Saudi population. This…”
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13
Molecular pathways in the development of HPV-induced oropharyngeal cancer
Published in Cell communication and signaling (14-12-2023)“…Oropharyngeal cancer, a subset of head and neck cancer, is increasingly recognized as a unique clinical entity primarily influenced by high-risk human…”
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Biological Role of Zinc in Liver Cirrhosis: An Updated Review
Published in Biomedicines (01-04-2023)“…Liver cirrhosis is a complication usually due to the consequence of persistent chronic liver disease. It is associated with different mechanisms, including…”
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Delineating Novel and Known Pathogenic Variants in TYR , OCA2 and HPS-1 Genes in Eight Oculocutaneous Albinism (OCA) Pakistani Families
Published in Genes (12-03-2022)“…Oculocutaneous albinism (OCA) is associated with a wide range of clinical presentations and has been categorized with syndromic and non-syndromic features. The…”
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Predicting Thalassemia Using Feature Selection Techniques: A Comparative Analysis
Published in Diagnostics (Basel) (01-11-2023)“…Thalassemia represents one of the most common genetic disorders worldwide, characterized by defects in hemoglobin synthesis. The affected individuals suffer…”
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Punishment of Theft in Islam and Its Enforcement In Pakistan
Published in Majallah-yi ʻulūm-i islāmiyyah va dīniyyah (Online) (30-06-2020)“…The Shari’ah classifies punishments into Ḥudūd, Qiṣāṣ, and Ta’zīr which aim to protect life, lineage, reason, property, and intellect in order to provide…”
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Identification and Functional Characterization of Mutation in FYCO1 in Families with Congenital Cataract
Published in Life (Basel, Switzerland) (21-08-2023)“…Congenital cataract (CC) causes a third of the cases of treatable childhood blindness worldwide. CC is a disorder of the crystalline lens which is established…”
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Hybrid Deep Learning Model for Endoscopic Lesion Detection and Classification Using Endoscopy Videos
Published in Diagnostics (Basel) (26-12-2021)“…In medical imaging, the detection and classification of stomach diseases are challenging due to the resemblance of different symptoms, image contrast, and…”
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In silico analysis of SIGMAR1 variant (rs4879809) segregating in a consanguineous Pakistani family showing amyotrophic lateral sclerosis without frontotemporal lobar dementia
Published in Neurogenetics (01-10-2015)“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and…”
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