Search Results - "Ulfat, M"
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Screening, biochemical characterization and antibiotics resistance/susceptibility of bacteria isolated from native soil and water samples
Published in Brazilian journal of biology (2024)“…The present study was conducted to isolate and characterize bacteria from water and soil sample taken from the Lahore Canal at different sites i.e. Mall Road,…”
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Mitochondrial disruption in isolated human monocytes: An underlying mechanism for cadmium-induced immunotoxicity
Published in Journal of immunotoxicology (01-12-2022)“…Cadmium (Cd) is an immunotoxic metal frequently found in the environment. The in vitro study undertaken here evaluated the immunotoxic effects of Cd in…”
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Therapeutic effect of combination vitamin D3 and siponimod on remyelination and modulate microglia activation in cuprizone mouse model of multiple sclerosis
Published in Frontiers in behavioral neuroscience (05-01-2023)“…Stimulation of remyelination is critical for the treatment of multiple sclerosis (MS) to alleviate symptoms and protect the myelin sheath from further damage…”
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Pirfenidone ameliorates ANIT-induced cholestatic liver injury via modulation of FXR, NF-кB/TNF-α, and Wnt/GSK-3β/β-catenin signaling pathways
Published in Toxicology and applied pharmacology (01-09-2024)“…Cholestasis is a hepatobiliary disorder characterized by the excessive accumulation of toxic bile acids in hepatocytes, leading to cholestatic liver injury…”
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Gut dysbiosis, inflammation and type 2 diabetes in mice using synthetic gut microbiota from diabetic humans
Published in Brazilian journal of biology (2023)“…Abstract The study was aimed to assess impact of high fat diet (HFD) and synthetic human gut microbiota (GM) combined with HFD and chow diet (CD) in inducing…”
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Modulation of the crosstalk between Keap1/Nrf2/HO-1 and NF-κB signaling pathways by Tomatidine protects against inflammation/oxidative stress-driven fulminant hepatic failure in mice
Published in International immunopharmacology (30-03-2024)“…[Display omitted] •Tomatidine has remarkable antioxidant and anti-inflammatory activities, protecting against fulminant hepatic failure in mice.•The interplay…”
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Protective effect of kaempferol glucoside against lipopolysaccharide-caused acute lung injury via targeting Nrf2/NF-κB/NLRP3/GSDMD: Integrating experimental and computational studies
Published in Saudi pharmaceutical journal (01-06-2024)“…The current study explored the protective potential of kaempferol 3-sophoroside-7-glucoside (KSG) against acute lung injury (ALI). Pre-treatment with KSG…”
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LC-MS characterization of bioactive metabolites from two Yemeni Aloe spp. with antioxidant and antidiabetic properties
Published in Arabian journal of chemistry (01-04-2020)“…Two Yemeni Aloe(s) have been investigated; the resin from A. perry Baker (APR, SocotranAloe), and the gel from A. vera (AVG, Saber Yamaniis). LC-MS for APR…”
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Salivary Hormones Leptin, Ghrelin, Glucagon, and Glucagon-Like Peptide 1 and Their Relation to Sweet Taste Perception in Diabetic Patients
Published in Journal of diabetes research (15-05-2023)“…Diabetes mellitus (DM) is one of the most common diseases worldwide. DM may disrupt hormone regulation. Metabolic hormones, leptin, ghrelin, glucagon, and…”
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Phyto-Phospholipid Conjugated Scorpion Venom Nanovesicles as Promising Carrier That Improves Efficacy of Thymoquinone against Adenocarcinoma Human Alveolar Basal Epithelial Cells
Published in Pharmaceutics (13-12-2021)“…Lung cancer is a dangerous type of cancer in men and the third leading cause of cancer-related death in women, behind breast and colorectal cancers…”
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Antiproliferative Activity of Egg Yolk Peptides in Human Colon Cancer Cells
Published in Nutrition and cancer (19-05-2017)“…Egg yolk peptides were successfully prepared from egg yolk protein by-products after lecithin extraction. Defatted egg yolk protein was hydrolyzed with pepsin…”
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Zein-Stabilized Nanospheres as Nanocarriers for Boosting the Aphrodisiac Activity of Icariin: Response Surface Optimization and In Vivo Assessment
Published in Pharmaceutics (16-06-2022)“…Icariin (ICA), a main active compound of the Epimedium genus, is used as an aphrodisiac in traditional Chinese herbal medicine. Despite its therapeutic…”
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Biochemical and histological effects of five weeks ingestion of Zamzam water on the liver and kidneys of Wistar rats
Published in Saudi pharmaceutical journal (01-01-2021)“…Zamzam water is a natural alkaline water which has become alkaline as a result of the natural environment. It comes from what is considered as one of the…”
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High Expression of Pd-1 in Circulating Cells of Patients With Advanced Colorectal Cancer Receiving Adjuvant Therapy
Published in Technology in cancer research & treatment (2020)“…Among all cancer types, colorectal cancer is the third most common in men and the second most common in women globally. Generally, the risk of colorectal…”
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ANTIOXIDANT ACTIVITY AND INHIBITORY EFFECT OF 2,4,4'-TRIHYDROXYCHALCONE ON DIGESTIVE ENZYMES RELATED TO OBESITY
Published in Slovenski veterinarski zbornik (01-01-2023)“…The aim of this study was to investigate the antioxidant activity and inhibitory effect of 2,4,4'-trihydroxychalcone on digestive enzymes related to obesity,…”
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Increased expressions of cellular ATP-binding cassette transporters may be a promising diagnostic marker for colorectal cancer
Published in Saudi medical journal (01-08-2020)“…To measure the blood expression levels of related drug-resistant ATP-binding cassette (ABC) transporters in colorectal cancer (CRC) patients and to assess…”
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Association between MDR1 polymorphisms and XELIRI and XELOX chemoresistance in Saudi patients with colorectal cancer
Published in Oncology letters (01-11-2020)“…Multidrug resistance member 1 (MDR1) is located on chromosome 7 and encodes P-glycoprotein, which is universally accepted as a drug resistance biomarker…”
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ABCB1 variants C3435T and T129C are not associated with colorectal cancer risk
Published in African health sciences (01-09-2019)“…Background: Colorectal cancer (CRC) is one of the most prevalent cancers in Saudi Arabia that is highly characterized with poor survival rate and advanced…”
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Novel association between heterozygous genotype of single nucleotide polymorphism C218T in drug transporter ABCC1 gene and increased risk of colon cancer
Published in Saudi medical journal (01-03-2019)“…To determine the role of G128C and C218T variants in ABCC1 gene with the risk of developing colon cancer in Jeddah, Kingdom of Saudi Arabia. Methods: This…”
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In Vitro Cytotoxic and Anticancer Effects of Zamzam Water in Human Lung Cancer (A594) Cell Line
Published in The Malaysian journal of medical sciences (01-05-2017)“…Zamzam water is naturally alkaline and rich in a variety of minerals which may represent a powerful tool for cancer therapy. In this research, the cytotoxic…”
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