Search Results - "Ul Amin, Toufiq"

Enhancing the Safety and Efficacy of PSMA-Based Small-Molecule Drug Conjugates by Linker Stabilization and Conjugation to Transthyretin Binding Ligand by Amin, Toufiq Ul, Emara, Rasha, Pal, Arindom, Aldawod, Hala, Jiang, Guanming, Liang, Dengpan, Haque Tuhin, Md Tariqul, Balgoname, Abdulmalek, Patel, Arjun D., Alhamadsheh, Mamoun M.

“…This work describes the enhancement of a novel antitumor therapeutic platform that combines advantages from small-molecule drug conjugates (SMDCs) and antibody…”
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Peripherally restricted transthyretin-based delivery system for probes and therapeutics avoiding opioid-related side effects by Tuhin, Md Tariqul Haque, Liang, Dengpan, Liu, Fang, Aldawod, Hala, Amin, Toufiq Ul, Ho, Joshua S., Emara, Rasha, Patel, Arjun D., Felmlee, Melanie A., Park, Miki S., Uchizono, James A., Alhamadsheh, Mamoun M.

“…Several investigations into the sites of action of opioid analgesics have utilized peripherally acting mu-opioid receptor antagonists (PAMORAs), which have…”
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Enhancing the Pharmacokinetic Profile of Interleukin 2 through Site-Specific Conjugation to a Selective Small-Molecule Transthyretin Ligand by Liu, Fang, Ul Amin, Toufiq, Liang, Dengpan, Park, Miki S, Alhamadsheh, Mamoun M

“…Protein drugs hold great promise as therapeutics for a wide range of diseases. Unfortunately, one of the greatest challenges to be addressed during clinical…”
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Hydrophilic Small Molecules That Harness Transthyretin To Enhance the Safety and Efficacy of Targeted Chemotherapeutic Agents by Pal, Arindom, Albusairi, Wabel, Liu, Fang, Tuhin, Md Tariqul Haque, Miller, Mark, Liang, Dengpan, Joo, Hyun, Amin, Toufiq Ul, Wilson, Elizabeth A, Faridi, Jesika S, Park, Miki, Alhamadsheh, Mamoun M

“…The hydrophobicity of many chemotherapeutic agents usually results in their nonselective passive distribution into healthy cells and organs causing collateral…”
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Incorporating Glutamic Acid-Valine-Citrulline Linker in Trifunctional Molecules Targeting PSMA Ensures Enhanced Stability, Safety, and Efficacy in Mouse Model of Prostate Cancer by Amin, Toufiq Ul

“…This project describes the development of a new antitumor therapeutic platform that combines the benefits of small-molecule drug conjugates (SMDCs) and…”
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