Search Results - "Uk‐Nham, Sang"
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Moieties of Complement iC3b Recognized by the I-domain of Integrin αXβ2
Published in Molecules and cells (31-12-2020)“…Complement fragment iC3b serves as a major opsonin for facilitating phagocytosis via its interaction with complement receptors CR3 and CR4, also known by their…”
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Characterization of the residues of αX I-domain and ICAM-1 mediating their interactions
Published in Molecules and cells (01-09-2010)“…Integrin αXβ2 performs a significant role in leukocyte functions including phagocytosis and migration, and binds to a variety of ligands, including fibrinogen,…”
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Characterization of αX I-Domain Binding to Receptors for Advanced Glycation End Products (RAGE)
Published in Molecules and cells (01-05-2017)“…The β2 integrins are cell surface transmembrane proteins regulating leukocyte functions, such as adhesion and migration. Two members of β2 integrin, αMβ2 and…”
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Direct Thy-1/αVβ3 integrin interaction mediates neuron to astrocyte communication
Published in Biochimica et biophysica acta. Molecular cell research (01-06-2008)“…Thy-1 is an abundant neuronal glycoprotein of poorly defined function. We recently provided evidence indicating that Thy-1 clusters a β3-containing integrin in…”
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Characterization of αX I-domain binding to Thy-1
Published in Biochemical and biophysical research communications (03-06-2005)“…The β2 integrins are found exclusively in leukocytes and they are composed of a common β chain, CD18, and one of four unique α chains, CD11a (αL subunit),…”
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A co‐operative interaction between Neisseria gonorrhoeae and complement receptor 3 mediates infection of primary cervical epithelial cells
Published in Cellular microbiology (01-09-2002)“…Summary Little is known about the pathogenesis of gonococcal infection within the lower female genital tract. We recently described the distribution of…”
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Critical residues of αX I-domain recognizing fibrinogen central domain
Published in Biochemical and biophysical research communications (20-04-2007)“…Integrin αXβ2 (CD11c/CD18), which binds several ligands such as fibrinogen and iC3b, has important roles in leukocyte functions including phagocytosis and…”
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Characteristics of Fibrinogen Binding to the Domain of CD11c, an α Subunit of p150,95
Published in Biochemical and biophysical research communications (02-11-1999)“…β2 integrins on leukocytes play important roles on cell–cell or cell–matrix adhesion through their ability to bind multiple ligands. The α subunits of…”
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Loops within the CD11c I Domain Critical for Specific Recognition of Fibrinogen
Published in Biochemical and biophysical research communications (05-04-2002)“…The I domains of CD11 are responsible for the binding of ligands and have a unique structure with 6-7 α helixes and 6 β sheets with interconnecting loops. To…”
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Isolation of hepatocyte stimulating factor from human monocytes
Published in Biochemical and biophysical research communications (29-04-1987)“…Hepatocyte stimulating factor is a monocyte derived protein which regulates hepatic plasma protein synthesis. Human hepatocyte stimulating factor was purified…”
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Rapid and simple purification of human immunodeficiency virus 1 epitope gp41
Published in Journal of virological methods (01-01-1993)“…In order to develop a reliable and inexpensive serodiagnostic method, part of the transmembrane glycoprotein gene of HIV-1, gp41', (HIV-env 548-646) was cloned…”
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Effect of fibrinogen degradation products on production of hepatocyte stimulating factor by a macrophage cell line (P388D1)
Published in Thrombosis research (15-11-1986)“…Hepatocyte Stimulating Factor (HSF) is a monocyte/macrophage-derived regulatory protein which stimulates the hepatic synthesis of several plasma proteins…”
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Cloning and characterization of cDNAs coding for heavy and light chains of agglutinating monoclonal antibody (HAG12) specific for human red blood cells
Published in Biochimica et biophysica acta (10-04-1998)“…Complementary DNAs encoding the heavy and light chains of the Fab fragment of mouse agglutinating monoclonal antibody against human red blood cells were cloned…”
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Structure of the human methylmalonyl-CoA mutase (MUT) locus
Published in Genomics (San Diego, Calif.) (1990)“…The MUT locus encoding the enzyme methylmalonyl-CoA mutase is defective in mut forms of methylmalonic acidemia. This locus has been mapped to chromosome…”
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Overexpression and purification of human immunodeficiency virus type 1 env derived epitopes in Escherichia coli
Published in Journal of biotechnology (08-03-1996)“…In order to develop a reliable and inexpensive serodiagnostic method, a part of envelope gene of HIV-1, gp120′ and gp41′ (HIV-1 env a.a. 295–474 and a.a…”
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Critical residues of alphaX I-domain recognizing fibrinogen central domain
Published in Biochemical and biophysical research communications (20-04-2007)“…Integrin alphaXbeta2 (CD11c/CD18), which binds several ligands such as fibrinogen and iC3b, has important roles in leukocyte functions including phagocytosis…”
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Characterization of alphaX I-domain binding to Thy-1
Published in Biochemical and biophysical research communications (03-06-2005)“…The beta2 integrins are found exclusively in leukocytes and they are composed of a common beta chain, CD18, and one of four unique alpha chains, CD11a (alphaL…”
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Characterization of {alpha}X I-domain binding to Thy-1
Published in Biochemical and biophysical research communications (03-06-2005)“…The {beta}2 integrins are found exclusively in leukocytes and they are composed of a common {beta} chain, CD18, and one of four unique {alpha} chains, CD11a…”
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Identification of critical residues for plasminogen binding by the alphaX I-domain of the beta2 integrin, alphaXbeta2
Published in Molecules and cells (31-10-2007)“…The beta2 integrins on leukocytes play important roles in cell adhesion, migration and phagocytosis. One of the beta2 integrins, alphaXbeta2 (CD11c/CD18), is…”
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