Search Results - "Uhm, Heesoo"

  • Showing 1 - 12 results of 12
Refine Results
  1. 1

    Quantification of purified endogenous miRNAs with high sensitivity and specificity by Shin, Soochul, Jung, Yoonseok, Uhm, Heesoo, Song, Minseok, Son, Soomin, Goo, Jiyoung, Jeong, Cherlhyun, Song, Ji-Joon, Kim, V. Narry, Hohng, Sungchul

    Published in Nature communications (27-11-2020)
    “…MicroRNAs (miRNAs) are short (19–24 nt) non-coding RNAs that suppress the expression of protein coding genes at the post-transcriptional level. Differential…”
    Get full text
    Journal Article
  2. 2

    Rho-dependent transcription termination proceeds via three routes by Song, Eunho, Uhm, Heesoo, Munasingha, Palinda Ruvan, Hwang, Seungha, Seo, Yeon-Soo, Kang, Jin Young, Kang, Changwon, Hohng, Sungchul

    Published in Nature communications (29-03-2022)
    “…Rho is a general transcription termination factor in bacteria, but many aspects of its mechanism of action are unclear. Diverse models have been proposed for…”
    Get full text
    Journal Article
  3. 3

    Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA by Kang, Wooyoung, Ha, Kook Sun, Uhm, Heesoo, Park, Kyuhyong, Lee, Ja Yil, Hohng, Sungchul, Kang, Changwon

    Published in Nature communications (23-01-2020)
    “…Despite extensive studies on transcription mechanisms, it is unknown how termination complexes are disassembled, especially in what order the essential…”
    Get full text
    Journal Article
  4. 4

    Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors by Yu, Nam-Kyung, Uhm, Heesoo, Shim, Jaehoon, Choi, Jun-Hyeok, Bae, Sangsu, Sacktor, Todd Charlton, Hohng, Sungchul, Kaang, Bong-Kiun

    Published in Molecular brain (29-11-2017)
    “…Protein kinase M zeta (PKMζ), a constitutively active, atypical protein kinase C isoform, maintains a high level of expression in the brain after the induction…”
    Get full text
    Journal Article
  5. 5

    Single-mode termination of phage transcriptions, disclosing bacterial adaptation for facilitated reinitiations by Song, Eunho, Han, Sun, Uhm, Heesoo, Kang, Changwon, Hohng, Sungchul

    Published in Nucleic acids research (16-07-2024)
    “…Abstract Bacterial and bacteriophage RNA polymerases (RNAPs) have divergently evolved and share the RNA hairpin-dependent intrinsic termination of…”
    Get full text
    Journal Article
  6. 6

    Single-molecule FRET studies on the cotranscriptional folding of a thiamine pyrophosphate riboswitch by Uhm, Heesoo, Kang, Wooyoung, Ha, Kook Sun, Kang, Changwon, 강창원, Hohng, Sungchul

    “…Because RNAs fold as they are being synthesized, their transcription rate can affect their folding. Here, we report the results of single-molecule fluorescence…”
    Get full text
    Journal Article
  7. 7
  8. 8

    RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding by Mazumder, Abhishek, Wang, Anna, Uhm, Heesoo, Ebright, Richard H, Kapanidis, Achillefs N

    Published in Nucleic acids research (18-03-2021)
    “…Abstract The RNA polymerase (RNAP) clamp, a mobile structural element conserved in RNAP from all domains of life, has been proposed to play critical roles at…”
    Get full text
    Journal Article
  9. 9
  10. 10

    Ligand Recognition Mechanism of Thiamine Pyrophosphate Riboswitch Aptamer by Uhm, Heesoo, Hohng, Sungchul

    Published in Bulletin of the Korean Chemical Society (01-12-2017)
    “…Riboswitches regulate gene expression by coupling ligand binding to a structural transition of the riboswitch, but the coupling mechanism is still…”
    Get full text
    Journal Article
  11. 11

    Multiple RPAs make WRN syndrome protein a superhelicase by Lee, Mina, Shin, Soochul, Uhm, Heesoo, Hong, Heesun, Kirk, Jaewon, Hyun, Kwangbeom, Kulikowicz, Tomasz, Kim, Jaehoon, Ahn, Byungchan, Bohr, Vilhelm A, Hohng, Sungchul

    Published in Nucleic acids research (18-05-2018)
    “…Abstract RPA is known to stimulate the helicase activity of Werner syndrome protein (WRN), but the exact stimulation mechanism is not understood. We use…”
    Get full text
    Journal Article
  12. 12