Search Results - "Uhlrich, Scott D"
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OpenCap: Human movement dynamics from smartphone videos
Published in PLoS computational biology (19-10-2023)“…Measures of human movement dynamics can predict outcomes like injury risk or musculoskeletal disease progression. However, these measures are rarely quantified…”
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Muscle coordination retraining inspired by musculoskeletal simulations reduces knee contact force
Published in Scientific reports (07-07-2022)“…Humans typically coordinate their muscles to meet movement objectives like minimizing energy expenditure. In the presence of pathology, new objectives gain…”
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3
Subject-specific toe-in or toe-out gait modifications reduce the larger knee adduction moment peak more than a non-personalized approach
Published in Journal of biomechanics (03-01-2018)“…The knee adduction moment (KAM) is a surrogate measure for medial compartment knee loading and is related to the progression of knee osteoarthritis. Toe-in and…”
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4
Smartphone videos of the sit-to-stand test predict osteoarthritis and health outcomes in a nationwide study
Published in NPJ digital medicine (04-03-2023)“…Physical function decline due to aging or disease can be assessed with quantitative motion analysis, but this currently requires expensive laboratory…”
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A scoping review of portable sensing for out-of-lab anterior cruciate ligament injury prevention and rehabilitation
Published in NPJ digital medicine (18-03-2023)“…Anterior cruciate ligament (ACL) injury and ACL reconstruction (ACLR) surgery are common. Laboratory-based biomechanical assessment can evaluate ACL injury…”
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Osteoarthritis year in review 2023: Biomechanics
Published in Osteoarthritis and cartilage (01-02-2024)“…Biomechanics plays a significant yet complex role in osteoarthritis (OA) onset and progression. Identifying alterations in biomechanical factors and their…”
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Ten steps to becoming a musculoskeletal simulation expert: A half-century of progress and outlook for the future
Published in Journal of biomechanics (01-06-2023)“…Over the past half-century, musculoskeletal simulations have deepened our knowledge of human and animal movement. This article outlines ten steps to becoming a…”
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8
Self-Supervised Learning Improves Accuracy and Data Efficiency for IMU-Based Ground Reaction Force Estimation
Published in IEEE transactions on biomedical engineering (01-07-2024)“…Objective: Recent deep learning techniques hold promise to enable IMU-driven kinetic assessment; however, they require large extents of ground reaction force…”
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Can static optimization detect changes in peak medial knee contact forces induced by gait modifications?
Published in Journal of biomechanics (01-05-2023)“…Medial knee contact force (MCF) is related to the pathomechanics of medial knee osteoarthritis. However, MCF cannot be directly measured in the native knee,…”
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10
Connecting the legs with a spring improves human running economy
Published in Journal of experimental biology (03-09-2019)“…Human running is inefficient. For every 10 calories burned, less than 1 is needed to maintain a constant forward velocity - the remaining energy is, in a…”
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Changes in foot progression angle during gait reduce the knee adduction moment and do not increase hip moments in individuals with knee osteoarthritis
Published in Journal of biomechanics (01-08-2022)“…People with knee osteoarthritis who adopt a modified foot progression angle (FPA) during gait often benefit from a reduction in the knee adduction moment. It…”
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Assessment of acute bone loading in humans using [18F]NaF PET/MRI
Published in European journal of nuclear medicine and molecular imaging (01-11-2019)“…Purpose The acute effect of loading on bone tissue and physiology can offer important information with regard to joint function in diseases such as…”
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Personalization improves the biomechanical efficacy of foot progression angle modifications in individuals with medial knee osteoarthritis
Published in Journal of biomechanics (01-11-2022)“…Modifying the foot progression angle during walking can reduce the knee adduction moment, a surrogate measure of medial knee loading. However, not all…”
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14
Rapid volumetric gagCEST imaging of knee articular cartilage at 3 T: evaluation of improved dynamic range and an osteoarthritic population
Published in NMR in biomedicine (01-08-2020)“…Chemical exchange saturation transfer of glycosaminoglycans, gagCEST, is a quantitative MR technique that has potential for assessing cartilage proteoglycan…”
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15
Simulating Muscle-Level Energetic Cost Savings When Humans Run With a Passive Assistive Device
Published in IEEE robotics and automation letters (01-10-2023)“…Connecting the legs with a spring attached to the shoelaces, called an exotendon, can reduce the energetic cost of running, but how the exotendon reduces the…”
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A neural network to predict the knee adduction moment in patients with osteoarthritis using anatomical landmarks obtainable from 2D video analysis
Published in Osteoarthritis and cartilage (01-03-2021)“…The knee adduction moment (KAM) can inform treatment of medial knee osteoarthritis; however, measuring the KAM requires an expensive gait analysis laboratory…”
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[18F]Sodium fluoride PET-MRI detects increased metabolic bone response to whole-joint loading stress in osteoarthritic knees
Published in Osteoarthritis and cartilage (01-11-2022)“…Altered joint function is a hallmark of osteoarthritis (OA). Imaging techniques for joint function are limited, but [18F]sodium fluoride (NaF) PET-MRI may…”
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Rapid Volumetric gagCEST Imaging of Knee Articular Cartilage at 3T: Evaluation of Improved Dynamic Range and an Osteoarthritic Population
Published in NMR in biomedicine (23-05-2020)“…Chemical exchange saturation transfer of glycosaminoglycans (GAG), gagCEST, is a quantitative MR technique that has potential for assessing cartilage…”
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Journal Article -
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Gait Modifications for Knee Osteoarthritis: Design, Evaluation, and Clinical Translation
Published 01-01-2020“…Knee osteoarthritis is a debilitating musculoskeletal disorder that profoundly impacts an individual’s physical health, mental health, and quality of life…”
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Dissertation -
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Ten Steps to Becoming a Musculoskeletal Simulation Expert: A Half-Century of Progress and Outlook for the Future
Published 01-06-2023“…J. Biomech. 154 (2023) 111623 Over the past half-century, musculoskeletal simulations have deepened our knowledge of human and animal movement. This article…”
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