Search Results - "Uhlin, Michael"

Cryopreserved Platelets in a Non-Toxic DMSO-Free Solution Maintain Hemostatic Function In Vitro by Ehn, Kristina, Wikman, Agneta, Uhlin, Michael, Sandgren, Per

“…Dimethyl sulfoxide (DMSO) is regularly used as a cryoprotectant agent for the cryopreservation of platelets. However, DMSO is considered toxic. We therefore…”
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Risk factors for Epstein-Barr virus-related post-transplant lymphoproliferative disease after allogeneic hematopoietic stem cell transplantation by Uhlin, Michael, Wikell, Helena, Sundin, Mikael, Blennow, Ola, Maeurer, Markus, Ringden, Olle, Winiarski, Jacek, Ljungman, Per, Remberger, Mats, Mattsson, Jonas

“…Allogeneic hematopoietic stem cell transplantation is a successful treatment for hematologic malignancies and a variety of genetic and metabolic disorders. In…”
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Human Vγ9Vδ2 T cell expansion and their cytotoxic responses against cholangiocarcinoma by Sawaisorn, Piamsiri, Gaballa, Ahmed, Saimuang, Kween, Leepiyasakulchai, Chaniya, Lertjuthaporn, Sakaorat, Hongeng, Suradej, Uhlin, Michael, Jangpatarapongsa, Kulachart

“…Human Vγ9Vδ2 T lymphocytes are regarded as promising effector cells for cancer immunotherapy since they have the ability to eliminate several tumor cells…”
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Immune profiling and identification of prognostic immune-related risk factors in human ovarian cancer by Rådestad, Emelie, Klynning, Charlotte, Stikvoort, Arwen, Mogensen, Ole, Nava, Silvia, Magalhaes, Isabelle, Uhlin, Michael

“…Suppression of immune reactivity by increased expression of co-inhibitory receptors has been discussed as a major reason as to why the immune system fails to…”
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Impact of γδ T cells on clinical outcome of hematopoietic stem cell transplantation: systematic review and meta-analysis by Arruda, Lucas C.M., Gaballa, Ahmed, Uhlin, Michael

“…Allogeneic hematopoietic stem cell transplantation (HSCT) using αβ T-/B-cell–depleted grafts recently emerged as a transplant strategy and highlighted the…”
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Inducing expression of ICOS-L by oncolytic adenovirus to enhance tumor-specific bi-specific antibody efficacy by Saffarzadeh, Neshat, Foord, Emelie, O'Leary, Eoghan, Mahmoun, Rand, Birkballe Hansen, Thomas, Levitsky, Victor, Poiret, Thomas, Uhlin, Michael

“…Intratumoral injection of oncolytic viruses (OVs) shows promise in immunotherapy: ONCOS-102, a genetically engineered OV that encodes Granulocyte-Macrophage…”
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Evaluating Thymic Function After Human Hematopoietic Stem Cell Transplantation in the Personalized Medicine Era by Gaballa, Ahmed, Clave, Emmanuel, Uhlin, Michael, Toubert, Antoine, Arruda, Lucas C M

“…Hematopoietic stem cell transplantation (HSCT) is an effective treatment option for several malignant and non-malignant hematological diseases. The clinical…”
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The allogeneic graft‐versus‐cancer effect by Ringdén, Olle, Karlsson, Helen, Olsson, Richard, Omazic, Brigitta, Uhlin, Michael

“…Summary Allogeneic haematological stem cell transplantation (HSCT) has developed into immunotherapy. Donor CD4+, CD8+ and natural killer (NK) cells have been…”
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Revisiting the Role of γδ T Cells in Anti-CMV Immune Response after Transplantation by Gaballa, Ahmed, Alagrafi, Faisal, Uhlin, Michael, Stikvoort, Arwen

“…Gamma delta (γδ) T cells form an unconventional subset of T lymphocytes that express a T cell receptor (TCR) consisting of γ and δ chains. Unlike conventional…”
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Modulation of lytic molecules restrain serial killing in γδ T lymphocytes by Sandoz, Patrick A., Kuhnigk, Kyra, Szabo, Edina K., Thunberg, Sarah, Erikson, Elina, Sandström, Niklas, Verron, Quentin, Brech, Andreas, Watzl, Carsten, Wagner, Arnika K., Alici, Evren, Malmberg, Karl-Johan, Uhlin, Michael, Önfelt, Björn

“…γδ T cells play a pivotal role in protection against various types of infections and tumours, from early childhood on and throughout life. They consist of…”
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Gamma delta T-cell reconstitution after allogeneic HCT: A platform for cell therapy by Gaballa, Ahmed, Arruda, Lucas C M, Uhlin, Michael

“…Allogeneic Hematopoietic stem cell transplantation (allo-HCT) is a curative platform for several hematological diseases. Despite its therapeutic benefits, the…”
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A novel CD34-specific T-cell engager efficiently depletes acute myeloid leukemia and leukemic stem cells in vitro and in vivo by Arruda, Lucas C M, Stikvoort, Arwen, Lambert, Melanie, Jin, Liqing, Rivera, Laura Sanchez, Alves, Renato M P, De Moura, Tales Rocha, Mim, Carsten, Lehmann, Sören, Axelsson-Robertson, Rebecca, Dick, John E, Mattsson, Jonas, Önfelt, Björn, Carlsten, Mattias, Uhlin, Michael

“…Less than a third of acute myeloid leukemia (AML) patients are cured by chemotherapy and/or hematopoietic stem cell transplantation (HSCT), highlighting the…”
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T cell receptor excision circles are potential predictors of survival in adult allogeneic hematopoietic stem cell transplantation recipients with acute myeloid leukemia by Söderström, Anna, Vonlanthen, Sofie, Jönsson-Videsäter, Kerstin, Mielke, Stephan, Lindahl, Hannes, Törlén, Johan, Uhlin, Michael

“…Background Lymphocyte neogenesis from primary lymphoid organs is essential for a successful reconstitution of immunity after allogeneic hematopoietic stem cell…”
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Mesenchymal stem cells fail to trigger effector functions of cytotoxic T lymphocytes by Rasmusson, Ida, Uhlin, Michael, Le Blanc, Katarina, Levitsky, Victor

“…Mesenchymal stem cells (MSCs), isolated from adult human bone marrow, have immunomodulatory properties. The functional outcomes of MSCs–CTL interactions remain…”
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Long-Term Stable Mixed Chimerism after Hematopoietic Stem Cell Transplantation in Patients with Non-Malignant Disease, Shall We Be Tolerant? by Stikvoort, Arwen, Sundin, Mikael, Uzunel, Mehmet, Gertow, Jens, Sundberg, Berit, Schaffer, Marie, Mattsson, Jonas, Uhlin, Michael

“…Long-term stable mixed chimerism is a rare and poorly understood phenomenon post hematopoietic stem cell transplantation. This study aims to shed light on…”
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CD8+γδ T Cells Are More Frequent in CMV Seropositive Bone Marrow Grafts and Display Phenotype of an Adaptive Immune Response by Uhlin, M., Rådestad, E., Arruda, Lucas C. M., Gaballa, Ahmed

“…The role of gamma delta (γδ) T cells in human cytomegalovirus (HCMV) immune surveillance has been the focus of research interest for years. Recent reports have…”
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Selective lysis of acute myeloid leukemia cells by CD34/CD3 bispecific antibody through the activation of γδ T-cells by Al Agrafi, Faisal, Gaballa, Ahmed, Hahn, Paula, Arruda, Lucas C M, Jaramillo, Adrian C, Witsen, Maartje, Lehmann, Sören, Önfelt, Björn, Uhlin, Michael, Stikvoort, Arwen

“…Despite the considerable progress in acute myeloid leukemia (AML) treatment, relapse after allogeneic hematopoietic stem cell transplantation (HSCT) is still…”
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Lymphocytes in Placental Tissues: Immune Regulation and Translational Possibilities for Immunotherapy by Erkers, Tom, Uhlin, M., Stikvoort, Arwen

“…Immune modulation at the fetomaternal interface is crucial to ensure that the fetal allograft is not rejected. In the present review, the focus is to describe…”
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Quality of the hematopoietic stem cell graft affects the clinical outcome of allogeneic stem cell transplantation by Watz, Emma, Remberger, Mats, Ringden, Olle, Ljungman, Per, Sundin, Mikael, Mattsson, Jonas, Uhlin, Michael

“…BACKGROUND In approximately two‐thirds of patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) no suitable related donor can be…”
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Expansion of Gammadelta T Cells from Cord Blood: A Therapeutical Possibility by Sundberg, B., Sawaisorn, Piamsiri, Gaballa, Ahmed, Berglund, Sofia, Uhlin, M.

“…Gammadelta (γδ) T cells are found in both blood and tissues and have antiviral and antitumor properties. The frequency of γδ T cells in umbilical cord blood…”
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