Search Results - "Uhlik, Jiri"

Baseline reticular basement membrane morphology is related to subsequent spirometry deterioration in pediatric chronic airway inflammation: a follow-up study by Koucký, Václav, Uhlík, Jiří, Hoňková, Lenka, Komárek, Arnošt, Pohunek, Petr

“…Reticular basement membrane (RBM) thickening may occur in children with allergic bronchial asthma (BA), cystic fibrosis (CF), and primary ciliary dyskinesia…”
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The possible role of hypoxia in the affected tissue of relapsed clubfoot by Novotny, Tomas, Eckhardt, Adam, Doubkova, Martina, Knitlova, Jarmila, Vondrasek, David, Vanaskova, Eliska, Ostadal, Martin, Uhlik, Jiri, Bacakova, Lucie, Musilkova, Jana

“…Our aim was to study the expression of hypoxia-related proteins as a possible regulatory pathway in the contracted side tissue of relapsed clubfoot. We…”
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Ventilation Inhomogeneity and Bronchial Basement Membrane Changes in Chronic Neutrophilic Airway Inflammation by Koucký, Václav, Uhlík, Jiří, Hoňková, Lenka, Koucký, Miroslav, Doušová, Tereza, Pohunek, Petr

“…Bronchial epithelial reticular basement membrane (RBM) thickening occurs in diseases with both eosinophilic (allergic bronchial asthma [BA]) and neutrophilic…”
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Oxidative Stress in the Developing Rat Brain due to Production of Reactive Oxygen and Nitrogen Species by Vajner, Luděk, Uhlík, Jiří, Vytášek, Richard, Wilhelm, Jiří

“…Oxidative stress after birth led us to localize reactive oxygen and nitrogen species (RONS) production in the developing rat brain. Brains were assessed a day…”
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The effect of exposure to hypoxia on superoxide formation by alveolar macrophages is indirect by Žaloudíková, Marie, Vytášek, Richard, Rašková, Marcela, Vízek, Martin, Uhlík, Jiří, Hampl, Václav

“…To elucidate the role of alveolar macrophages (AM) in the pathogenesis of hypoxic pulmonary hypertension (HPH), we tested the effects of sustained hypoxia on…”
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Structural changes in the bronchial mucosa of young children at risk of developing asthma by Berankova, Katarina, Uhlik, Jiri, Honkova, Lenka, Pohunek, Petr

“…Background Bronchial asthma often starts in early childhood. Clinical manifestation of the disease is likely due to inflammatory processes in the airways…”
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Epithelial basement membrane thickening is related to TGF-Beta 1 expression in children with chronic respiratory diseases by Hoňková, Lenka, Uhlík, Jiří, Beránková, Katarína, Svobodová, Tamara, Pohunek, Petr

“…Background The complex structural changes of bronchial mucosa, known as remodelling, have been considered unique and typical for asthma. However, similar…”
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Four-day pulse of sodium cromoglycate modulates pulmonary vessel wall remodeling during 21-day hypoxia in rats by Novotný, Tomáš, Uhlík, Jiří, Vajner, Luděk

“…Aim of the study: Remodeling of pulmonary resistance arteries in rats due to 4-day hypoxia could be successfully suppressed by sodium cromoglycate. In this…”
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The Role of Cryotherapy in Vitreous Concentrations of Topotecan Delivered by Episcleral Hydrogel Implant by Kodetova, Martina, Hobzova, Radka, Sirc, Jakub, Uhlik, Jiri, Dunovska, Katerina, Svojgr, Karel, Cocarta, Ana-Irina, Felsoova, Andrea, Slanar, Ondrej, Sima, Martin, Kozak, Igor, Pochop, Pavel

“…Transscleral diffusion delivery of chemotherapy is a promising way to reach the vitreal seeds of retinoblastoma, the most common intraocular malignancy in…”
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Does the articularis cubiti muscle really exist? Anatomical, histological, and magnetic resonance imaging study with a narrative review of literature by Benes, Michal, Novotny, Tomas, Kachlik, David, Uhlik, Jiri, Kunc, Vojtech

“…Although the term articularis cubiti muscle is incorporated in the official anatomical nomenclature, only sparse data about its appearance are available. It is…”
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Effect of Inhalation of Single Dose of Beclomethasone on Airway Epithelium by Uhlík, Ji í, Vajner, Lud k, Adášková, Jana, Konrádová, Václava

“…Inhaled corticosteroids are being recommended for the treatment of bronchial asthma for their anti-inflammatory properties and reduction of airway…”
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IL-7/αIL-7 mAb M25 immunocomplexes expand CD8+ T cells but paradoxically abrogate the antitumor activity of CTLA-4 and PD-1 blockage by Hrabos, Dominik, Hnizdilova, Tereza, Tomala, Jakub, Uhlik, Jiri, Kovar, Marek

“…•IL-7/M25 shift the CD8+:CD4+ T cell ratio in favor of CD8+ T cells.•IL-7/M25 and checkpoint inhibitors increase the infiltration of tumor by CD8+ T…”
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Increased Microvessel and Arteriole Density in the Contracted Side of the Relapsed Clubfoot by Novotny, Tomas, Eckhardt, Adam, Knitlova, Jarmila, Doubkova, Martina, Ostadal, Martin, Uhlik, Jiri, Musilkova, Jana

“…BACKGROUND:Clubfoot deformity (pes equinovarus) is one of the most common birth defects, and its etiology is still unknown. Initial clubfoot treatment is based…”
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Hydrogel implants for transscleral diffusion delivery of topotecan: In vivo proof of concept in a rabbit eye model by Hobzova, Radka, Kodetova, Martina, Pochop, Pavel, Uhlik, Jiri, Dunovska, Katerina, Svojgr, Karel, Hrabeta, Jan, Feriancikova, Barbara, Cocarta, Ana-Irina, Sirc, Jakub

“…[Display omitted] •Fabricated hydrogel implant consists of a drug-loaded layer and a protective layer.•Implants were surgically administered to the posterior…”
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2‐Hydroxyethyl Methacrylate Hydrogels for Local Drug Delivery: Study of Topotecan and Vincristine Sorption/Desorption Kinetics and Polymer‐Drug Interaction by ATR‐FTIR Spectroscopy by Cocarta, Ana‐Irina, Hobzova, Radka, Trchova, Miroslava, Svojgr, Karel, Kodetova, Martina, Pochop, Pavel, Uhlik, Jiri, Sirc, Jakub

“…Poly(2‐hydroxyethyl methacrylate) (pHEMA) hydrogels are well known in ophthalmological applications and recently investigated as drug delivery systems. The…”
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Novel contribution to clubfoot pathogenesis: The possible role of extracellular matrix proteins by Eckhardt, Adam, Novotny, Tomas, Doubkova, Martina, Hronkova, Lucia, Vajner, Ludek, Pataridis, Statis, Hadraba, Daniel, Kulhava, Lucie, Plencner, Martin, Knitlova, Jarmila, Liskova, Jana, Uhlik, Jiri, Zaloudikova, Marie, Vondrasek, David, Miksik, Ivan, Ostadal, Martin

“…ABSTRACT Idiopathic pes equinovarus (clubfoot) is a congenital deformity of the feet and lower legs. Clubfoot belongs to a group of fibro‐proliferative…”
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Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells by HRABETA, JAN, GROH, TOMAS, KHALIL, MOHAMED ASHRAF, POLJAKOVA, JITKA, ADAM, VOJTECH, KIZEK, RENE, UHLIK, JIRI, DOKTOROVA, HELENA, CERNA, TEREZA, FREI, EVA, STIBOROVA, MARIE, ECKSCHLAGER, TOMAS

“…Neuroblastoma is the most common cancer in infants and the fourth most common cancer in children. Aggressive cell growth and chemoresistance are notorious…”
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Simple model of pulmonary hypertension secondary to left heart pressure overload induced by partial intravascular occlusion of the ascending aorta by Chovanec, Milan, Ďurišová, Jana, Vajnerová, Olga, Baňasová, Alena, Vízek, Martin, Žaloudíková, Marie, Uhlík, Jiří, Krása, Kryštof, Herget, Jan, Hampl, Václav

“…Pulmonary hypertension is a group of diseases characterized by elevated pulmonary artery pressure and pulmonary vascular resistance with significant morbidity…”
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EXPRESS: Decreased collagen VI in the tunica media of pulmonary vessels during exposure to hypoxia - a novel step in pulmonary arterial remodeling by Zaloudikova, Marie, Eckhardt, Adam, Vytasek, Richard, Uhlik, Jiri, Novotny, Tomas, Bacakova, Lucie, Musilkova, Jana, Hampl, Vaclav

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An effective combination of sanger and next generation sequencing in diagnostics of primary ciliary dyskinesia by Djakow, Jana, Kramná, Lenka, Dušátková, Lenka, Uhlík, Jiří, Pursiheimo, Juha-Pekka, Svobodová, Tamara, Pohunek, Petr, Cinek, Ondřej

“…Summary Background Primary ciliary dyskinesia (PCD) is a multigenic autosomal recessive condition affecting respiratory tract and other organs where ciliary…”
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