Search Results - "Ugolin, Nicolas"
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Biodosimetry in interventional radiology: cutaneous-based immunoassay for anticipating risks of dermatitis
Published in European radiology (01-10-2021)“…Objectives Interventional radiology procedures expose individuals to ionizing radiation. However, existing dosimetry methods do not provide the dose…”
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Comparative analysis of micro-RNAs in human papillomavirus-positive versus -negative oropharyngeal cancers
Published in Head & neck (01-11-2016)“…Background Oncogenic mechanisms of human papillomavirus (HPV)‐positive oropharyngeal cancer are still poorly characterized. Analysis of their microRNA…”
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3
A transcriptome signature distinguished sporadic from postradiotherapy radiation-induced sarcomas
Published in Carcinogenesis (New York) (01-06-2011)“…Exposure to ionizing radiation is a known risk factor for cancer. However, up to now, rigorously defined scientific criteria that could establish case-by-case…”
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A predictive transcriptomic signature of oropharyngeal cancer according to HPV16 status exclusively
Published in Oral oncology (01-11-2014)“…Summary Objective Human-papillomaviruses (HPV) type 16 is a causative agent in an increasing subset of oropharyngeal squamous cell carcinomas (OPSCCs). These…”
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Gene expression profiling of alpha‐radiation‐induced rat osteosarcomas: Identification of dysregulated genes involved in radiation‐induced tumorigenesis of bone
Published in International journal of cancer (01-08-2009)“…To better understand the molecular basis of radiation‐induced osteosarcoma (OS), we performed global gene expression profiling of rat OS tumors induced by the…”
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Puma and Trail/Dr5 pathways control radiation-induced apoptosis in distinct populations of testicular progenitors
Published in PloS one (12-08-2010)“…Spermatogonia- stem cells and progenitors of adult spermatogenesis- are killed through a p53-regulated apoptotic process after gamma-irradiation but the death…”
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Strategy to find molecular signatures in a small series of rare cancers: validation for radiation-induced breast and thyroid tumors
Published in PloS one (11-08-2011)“…Methods of classification using transcriptome analysis for case-by-case tumor diagnosis could be limited by tumor heterogeneity and masked information in the…”
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Gene expression signature discriminates sporadic from post-radiotherapy-induced thyroid tumors
Published in Endocrine-related cancer (01-02-2011)“…Both external and internal exposure to ionizing radiation are strong risk factors for the development of thyroid tumors. Until now, the diagnosis of…”
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BOOSTER: Development of a Toolbox for Triage of Large Groups of Individuals Exposed to Radioactive Material
Published in IEEE transactions on nuclear science (01-08-2014)“…The effective management of an event involving the exposure of a large number of people to radioactive material requires a mechanism for fast triage of exposed…”
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10
Transcriptional Response of Wild-Type and Ataxia Telangiectasia Lymphoblasts Following Exposure to Equitoxic doses of Ionizing Radiation
Published in JOURNAL OF RADIATION RESEARCH (2006)“…Experiments were designed to compare the transcriptional response to ionizing radiation (IR) of wild-type (WT) and ataxia telangiectasia (AT) cells. mRNA…”
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Gene Expression Profiling of Differentiated Thyroid Neoplasms
Published in Clinical cancer research (01-10-2004)“…Purpose: The purpose of this research was to identify novel genes that can be targeted as diagnostic and clinical markers of differentiated thyroid tumors…”
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12
Deregulated Pathways in a Human Lymphoblastoid Cell Line after Low Doses of Gamma Irradiation
Published in Cancer genomics & proteomics (01-09-2006)“…Transcriptome analysis now permits the exploration of the effects of low doses of radiation and potentially can provide a global view of radiation responsive…”
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13
DosiKit, a New Immunoassay for Fast Radiation Biodosimetry of Hair and Blood Samples
Published in Radiation research (01-11-2018)“…DosiKit is a field radiation biodosimetry immunoassay for fast triage of individuals exposed to external total-body or partial-body irradiation (TBI or PBI)…”
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DosiKit, a New Portable Immunoassay for Fast External Irradiation Biodosimetry
Published in Radiation research (01-08-2018)“…DosiKit is a new field-radiation biodosimetry immunoassay for rapid triage of individuals exposed to external total-body irradiation. Here, we report on the…”
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15
Aging and photo-aging DNA repair phenotype of skin cells-evidence toward an effect of chronic sun-exposure
Published in Mutation research (01-08-2012)“…Several studies have demonstrated the deleterious effect of aging on the capacity of cells to repair their DNA. However, current existing assays aimed at…”
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Comparison of transcriptomic signature of post-Chernobyl and postradiotherapy thyroid tumors
Published in Thyroid (New York, N.Y.) (01-11-2013)“…We previously identified two highly discriminating and predictive radiation-induced transcriptomic signatures by comparing series of sporadic and…”
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Are adenosquamous lung carcinomas a simple mix of adenocarcinomas and squamous cell carcinomas, or more complex at the molecular level?
Published in Lung cancer (Amsterdam, Netherlands) (01-04-2010)“…Abstract Adenocarcinomas (AC), squamous cell carcinomas (SCC) and adenosquamous carcinomas (ASC) are three histological subtypes of non-small-cell lung…”
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18
Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance
Published in Oncotarget (18-04-2017)“…Cancer cells can use a telomerase-independent mechanism, known as alternative lengthening of telomeres (ALT), to elongate their telomeres. General control…”
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Use of gene expression signature to discriminate oropharyngeal cancers according to HPV16 status
Published in Journal of clinical oncology (20-05-2013)“…Abstract only 6055 Background: Strong evidence supports the hypothesis that high-risk human papillomavirus (HPV), particularly HPV16, is a causative agent for…”
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Gene expression profiling of differentiated thyroid neoplasms: Diagnostic and clinical implications
Published in Clinical cancer research (01-10-2004)“…The purpose of this research was to identify novel genes that can be targeted as diagnostic and clinical markers of differentiated thyroid tumors. Gene…”
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