Search Results - "Ugocsai, Melinda"
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Conjugation with Tris Decreases the Risk of Ketoprofen-Induced Mucosal Damage and Reduces Inflammation-Associated Methane Production in a Rat Model of Colitis
Published in Pharmaceutics (01-09-2023)“…We have designed a new compound from the non-steroidal anti-inflammatory drug (NSAID) ketoprofen (Ket) and 2-amino-2-(hydroxymethyl)-1,3-propanediol (Tris)…”
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Journal Article -
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Detection of Intestinal Tissue Perfusion by Real-Time Breath Methane Analysis in Rat and Pig Models of Mesenteric Circulatory Distress
Published in Critical care medicine (01-05-2019)“…Methane (CH4) breath test is an established diagnostic method for gastrointestinal functional disorders. Our aim was to explore the possible link between…”
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Journal Article -
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Reduced mucosal side-effects of acetylsalicylic acid after conjugation with tris-hydroxymethyl-aminomethane. Synthesis and biological evaluation of a new anti-inflammatory compound
Published in European journal of pharmacology (15-06-2016)“…Acetylsalicylic acid (ASA) causes adverse haemorrhagic reactions in the upper gastrointestinal (GI) tract, and previous results have suggested that combination…”
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Journal Article -
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Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis
Published in Inflammopharmacology (01-02-2018)“…Background We have developed a novel compound from acetylsalicylic acid (ASA) and 2-amino-2-(hydroxymethyl)-1,3-propanediol (Tris) precursors with ASA-like…”
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Journal Article -
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Kálcium-foszfát es kálcium-oxalát kristályok megjelenése kórosan elváltozott emberi szövetekben: Uj diagnosztikai lehetőség
Published 01-01-1986“…Jóindulatú és rosszindulatú emlőbetegségek mikrokalcifikdcióinak elemi összetételét vizsgáltuk3 s megállapitottuk3 hogy a rákos elváltozások kalcifikációi…”
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Dissertation