Search Results - "Ugarte‐Uribe, Begoña"

DRP1 interacts directly with BAX to induce its activation and apoptosis by Jenner, Andreas, Peña‐Blanco, Aida, Salvador‐Gallego, Raquel, Ugarte‐Uribe, Begoña, Zollo, Cristiana, Ganief, Tariq, Bierlmeier, Jan, Mund, Markus, Lee, Jason E, Ries, Jonas, Schwarzer, Dirk, Macek, Boris, Garcia‐Saez, Ana J

“…The apoptotic executioner protein BAX and the dynamin‐like protein DRP1 co‐localize at mitochondria during apoptosis to mediate mitochondrial permeabilization…”
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Chemigenetic Far-Red Labels and Ca2+ Indicators Optimized for Photoacoustic Imaging by Cook, Alexander, Kaydanov, Nikita, Ugarte-Uribe, Begoña, Boffi, Juan Carlos, Kamm, Gretel B., Prevedel, Robert, Deo, Claire

“…Photoacoustic imaging is an emerging modality with significant promise for biomedical applications such as neuroimaging, owing to its capability to capture…”
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Apoptotic foci at mitochondria: in and around Bax pores by Ugarte-Uribe, Begoña, García-Sáez, Ana J.

“…The permeabilization of the mitochondrial outer membrane by Bax and Bak during apoptosis is considered a key step and a point of no return in the signalling…”
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Drp1 polymerization stabilizes curved tubular membranes similar to those of constricted mitochondria by Ugarte-Uribe, Begoña, Prévost, Coline, Das, Kushal Kumar, Bassereau, Patricia, García-Sáez, Ana J

“…Drp1, an 80-kDa mechanochemical GTPase of the dynamin superfamily, is required for mitochondrial division in mammals. Despite the role of Drp1 dysfunction in…”
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Conjugative Coupling Proteins and the Role of Their Domains in Conjugation, Secondary Structure and in vivo Subcellular Location by Álvarez-Rodríguez, Itxaso, Ugarte-Uribe, Begoña, de la Arada, Igor, Arrondo, José Luis R., Garbisu, Carlos, Alkorta, Itziar

“…Type IV Coupling Proteins (T4CPs) are essential elements in many type IV secretion systems (T4SSs). The members of this family display sequence, length, and…”
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Type IV Coupling Proteins as Potential Targets to Control the Dissemination of Antibiotic Resistance by Álvarez-Rodríguez, Itxaso, Arana, Lide, Ugarte-Uribe, Begoña, Gómez-Rubio, Elena, Martín-Santamaría, Sonsoles, Garbisu, Carlos, Alkorta, Itziar

“…The increase of infections caused by multidrug-resistant bacteria, together with the loss of effectiveness of currently available antibiotics, represents one…”
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Double-tailed lipid modification as a promising candidate for oligonucleotide delivery in mammalian cells by Ugarte-Uribe, Begoña, Grijalvo, Santiago, Busto, Jon V., Martín, César, Eritja, Ramón, Goñi, Félix M., Alkorta, Itziar

“…The potential use of nucleic acids as therapeutic drugs has triggered the quest for oligonucleotide conjugates with enhanced cellular permeability. To this…”
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Synthesis, Cell-Surface Binding, and Cellular Uptake of Fluorescently Labeled Glucose−DNA Conjugates with Different Carbohydrate Presentation by Ugarte-Uribe, Begoña, Pérez-Rentero, Sonia, Lucas, Ricardo, Aviñó, Anna, Reina, José J, Alkorta, Itziar, Eritja, Ramón, Morales, Juan C

“…Oligonucleotide conjugates carrying carbohydrates at the 5′-end have been prepared. Glucose, fucose, and saccharides containing glucose at the nonreducing end…”
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BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL by Flores-Romero, Hector, Landeta, Olatz, Ugarte-Uribe, Begoña, Cosentino, Katia, García-Porras, Miguel, García-Sáez, Ana J., Basañez, Gorka

“…BFL1 is a relatively understudied member of the BCL2 protein family which has been implicated in the pathogenesis and chemoresistance of a variety of human…”
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Dynamin-related Protein 1 (Drp1) Promotes Structural Intermediates of Membrane Division by Ugarte-Uribe, Begoña, Müller, Hans-Michael, Otsuki, Miki, Nickel, Walter, García-Sáez, Ana J.

“…Drp1 is a dynamin-like GTPase that mediates mitochondrial and peroxisomal division in a process dependent on self-assembly and coupled to GTP hydrolysis…”
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Membranes in motion: mitochondrial dynamics and their role in apoptosis by Ugarte-Uribe, Begoña, García-Sáez, Ana J

“…Mitochondrial dynamics is crucial for cell survival, development and homeostasis and impairment of these functions leads to neurologic disorders and metabolic…”
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Chemigenetic Far-Red Labels and Ca 2+ Indicators Optimized for Photoacoustic Imaging by Cook, Alexander, Kaydanov, Nikita, Ugarte-Uribe, Begoña, Boffi, Juan Carlos, Kamm, Gretel B, Prevedel, Robert, Deo, Claire

“…Photoacoustic imaging is an emerging modality with significant promise for biomedical applications such as neuroimaging, owing to its capability to capture…”
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Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms by Ugarte-Uribe, Begoña, Grijalvo, Santiago, Pertíñez, Samuel Núñez, Busto, Jon V., Martín, César, Alagia, Adele, Goñi, Félix M., Eritja, Ramón, Alkorta, Itziar

“…[Display omitted] The ability of oligonucleotides to silence specific genes or inhibit the biological activity of specific proteins has generated great…”
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The transmembrane domain of the T4SS coupling protein TrwB and its role in protein–protein interactions by Segura, Rosa L., Águila-Arcos, Sandra, Ugarte-Uribe, Begoña, Vecino, Ana J., de la Cruz, Fernando, Goñi, Félix M., Alkorta, Itziar

“…Bacteria use type IV secretion systems to transfer genetic material and proteins from donor to recipient cells, using proteins encoded by conjugative plasmids…”
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Subcellular location of the coupling protein TrwB and the role of its transmembrane domain by Segura, Rosa L., Águila-Arcos, Sandra, Ugarte-Uribe, Begoña, Vecino, Ana J., de la Cruz, Fernando, Goñi, Félix M., Alkorta, Itziar

“…Conjugation is the most important mechanism for horizontal gene transfer and it is the main responsible for the successful adaptation of bacteria to the…”
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Does Ceramide Form Channels? The Ceramide-Induced Membrane Permeabilization Mechanism by Artetxe, Ibai, Ugarte-Uribe, Begoña, Gil, David, Valle, Mikel, Alonso, Alicia, García-Sáez, Ana J., Goñi, Félix M.

“…Ceramide is a sphingolipid involved in several cellular processes, including apoptosis. It has been proposed that ceramide forms large and stable channels in…”
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Reconstitution in liposome bilayers enhances nucleotide binding affinity and ATP-specificity of TrwB conjugative coupling protein by Vecino, Ana J., Segura, Rosa L., Ugarte-Uribe, Begoña, Águila, Sandra, Hormaeche, Itsaso, la Cruz, Fernando de, Goñi, Félix M., Alkorta, Itziar

“…Bacterial conjugative systems code for an essential membrane protein that couples the relaxosome to the DNA transport apparatus, called type IV coupling…”
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Reconstitution into liposomes enhances nucleotide binding affinity of TrwB conjugative coupling protein by Segura, Rosa de Lima, Vecino, Ana Julia, Ugarte-Uribe, Begoña, Águila, Sandra, de la Cruz, Fernando, Goñi, Félix M., Alkorta, Itziar

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