Search Results - "Uffelman, K. D."

Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans by Lewis, G F, Uffelman, K D, Szeto, L W, Weller, B, Steiner, G

“…Changes in VLDL triglyceride and VLDL apo B production were determined semiquantitatively in healthy young men by examining the effect of altering plasma…”
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Postprandial remnant-like lipoproteins in hypertriglyceridemia by OOI, T. C, COUSINS, M, OOI, D. S, STEINER, G, UFFELMAN, K. D, NAKAJIMA, K, SIMO, I. E

“…It has been proposed that remnants of chylomicrons and very-low-density lipoproteins (VLDL) are atherogenic. We have used an immunochemical method to isolate…”
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VLDL production is decreased to a similar extent by acute portal vs. peripheral venous insulin by Lewis, G F, Zinman, B, Uffelman, K D, Szeto, L, Weller, B, Steiner, G

“…Acute changes in very low-density lipoprotein (VLDL) triglyceride (TG) and VLDL apolipoprotein (apo) B production were examined in 11 healthy young males in…”
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Triglyceride enrichment of HDL does not alter HDL-selective cholesteryl ester clearance in rabbits by Rashid, S, Uffelman, K D, Barrett, P H, Vicini, P, Adeli, K, Lewis, G F

“…Triglyceride (TG) enrichment of high density lipoprotein (HDL), which occurs in hypertriglyceridemic states, significantly enhances the rate at which HDL…”
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Clearance of postprandial and lipolytically modified human HDL in rabbits and rats by Lewis, G F, Lamarche, B, Uffelman, K D, Heatherington, A C, Honig, M A, Szeto, L W, Barrett, P H

“…Triglyceride (TG) enrichment of high density lipoproteins (HDL) in hypertriglyceridemic states renders the particles vulnerable to lipolysis, which reduces…”
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Production of small high-density lipoprotein particles after stimulation of in vivo lipolysis in hypertriglyceridemic individuals: Studies before and after triglyceride-lowering therapy by Lewis, G.F., Uffelman, K.D., Lamarche, B., Cabana, V.G., Getz, G.S.

“…In hypertriglyceridemic states, triglyceride enrichment of high-density lipoprotein (HDL) may play an important role in decreasing the HDL cholesterol and…”
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Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men by Lamarche, B, Uffelman, K D, Carpentier, A, Cohn, J S, Steiner, G, Barrett, P H, Lewis, G F

“…Triglyceride (TG) enrichment of HDL resulting from cholesteryl ester transfer protein-mediated exchange with TG-rich lipoproteins may enhance the lipolytic…”
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Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL ApoB production in normal weight and obese individuals by LEWIS, G. F, UFFELMAN, K. D, SZETO, L. W, STEINER, G

“…The effects of short-term hyperinsulinemia on the production of both VLDL triglyceride and VLDL apoB were determined semiquantitatively before and during a 6-h…”
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Important contribution of lipoprotein particle number to plasma triglyceride concentration in type 2 diabetes by Steiner, George, Tkáč, Ivan, Uffelman, Kristine D, Lewis, Gary F

“…The aim of the present study was to determine the contributions of particle size versus number to differences in plasma triglyceride-rich lipoprotein…”
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Vasopeptidase inhibitor omapatrilat induces profound insulin sensitization and increases myocardial glucose uptake in Zucker fatty rats: Studies comparing a vasopeptidase inhibitor, angiotensin-converting enzyme inhibitor, and angiotensin II type I receptor blocker by WANG, Chao-Hung, LEUNG, Nathalie, LAPOINTE, Nathalie, SZETO, Linda, UFFELMAN, Kristine D, GIACCA, Adria, ROULEAU, Jean L, LEWIS, Gary F

“…ACE inhibitors (ACEIs) improve insulin resistance and prevent type 2 diabetes, possibly mediated by inhibition of bradykinin (BK) degradation. The…”
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Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL apoB production in normal weight and obese individuals by Lewis, G. F., Uffelman, K. D., Szeto, L. W., Steiner, G.

“…Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL apoB production in normal weight and obese individuals. G F Lewis , K D Uffelman , L W Szeto…”
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The Effect of Systemic Versus Portal Insulin Delivery in Pancreas Transplantation on Insulin Action and VLDL Metabolism by CARPENTIER, André, PATTERSON, Bruce W, UFFELMAN, Kristine D, GIACCA, Adria, VRANIC, Mladen, CATTRAL, Mark S, LEWIS, Gary F

“…The Effect of Systemic Versus Portal Insulin Delivery in Pancreas Transplantation on Insulin Action and VLDL Metabolism André Carpentier 1 , Bruce W. Patterson…”
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Expression of human hepatic lipase in the rabbit model preferentially enhances the clearance of triglyceride-enriched versus native high-density lipoprotein apolipoprotein A-I by RASHID, Shirya, TRINH, Denny K, UFFELMAN, Kristine D, COHN, Jeffrey S, RADER, Daniel J, LEWIS, Gary F

“…We have shown previously that triglyceride (TG) enrichment of HDL, as occurs in hypertriglyceridemic states, contributes to HDL lowering in humans by enhancing…”
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Apolipoprotein B-48 and retinyl palmitate are not equivalent markers of postprandial intestinal lipoproteins by Lemieux, S, Fontani, R, Uffelman, K D, Lewis, G F, Steiner, G

“…This study compared retinyl palmitate and apolipoprotein (apo) B-48 as markers of postprandial triglyceride-rich lipoproteins. Nine non-diabetic men received…”
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Mechanism of HDL lowering in insulin resistant states by Lewis, G F, Rashid, S, Uffelman, K D, Lamarche, B

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Improved method for quantitation of B apoprotein in plasma lipoproteins by electroimmunoassay by Reardon, M F, Poapst, M E, Uffelman, K D, Steiner, G

“…The B apoprotein occurs in a wide range of plasma lipoproteins, which are heterogenous both with respect to size and to composition. Immunochemical recognition…”
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Analysis of particle size and lipid composition as determinants of the metabolic clearance of human high density lipoproteins in a rabbit model by Lamarche, B, Uffelman, K D, Steiner, G, Barrett, P H, Lewis, G F

“…Hypertriglyceridemia is commonly associated with triglyceride (TG) enrichment of high density lipoprotein (HDL) and reduction in HDL cholesterol and…”
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Rate of Production of Plasma and Very-Low-Density Lipoprotein (VLDL) Apolipoprotein C-III Is Strongly Related to the Concentration and Level of Production of VLDL Triglyceride in Male Subjects with Different Body Weights and Levels of Insulin Sensitivity by Cohn, Jeffrey S., Patterson, Bruce W., Uffelman, Kris D., Davignon, Jean, Steiner, George

“…Overweight individuals with reduced insulin sensitivity often have mild to moderate hypertriglyceridemia. To investigate the role of apolipoprotein (apo)C-III…”
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Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction by Haidari, Mehran, Leung, Nathalie, Mahbub, Farhana, Uffelman, Kristine D, Kohen-Avramoglu, Rita, Lewis, Gary F, Adeli, Khosrow

“…Insulin-resistant states are characterized by hypertriglyceridemia, predominantly because of overproduction of hepatic very low density lipoprotein particles…”
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Ameliorated Hepatic Insulin Resistance Is Associated with Normalization of Microsomal Triglyceride Transfer Protein Expression and Reduction in Very Low Density Lipoprotein Assembly and Secretion in the Fructose-fed Hamster by Carpentier, Andre, Taghibiglou, Changiz, Leung, Nathalie, Szeto, Linda, Van Iderstine, Stephen C, Uffelman, Kristine D, Buckingham, Robin, Adeli, Khosrow, Lewis, Gary F

“…To determine whether reduction of insulin resistance could ameliorate fructose-induced very low density lipoprotein (VLDL) oversecretion and to explore the…”
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