Search Results - "Uemura, Mamoru"

The Geriatric Nutritional Risk Index predicts postoperative complications and prognosis in elderly patients with colorectal cancer after curative surgery by Sasaki, Masaru, Miyoshi, Norikatsu, Fujino, Shiki, Ogino, Takayuki, Takahashi, Hidekazu, Uemura, Mamoru, Matsuda, Chu, Yamamoto, Hirofumi, Mizushima, Tsunekazu, Mori, Masaki, Doki, Yuichiro

“…Malnutrition has been considered to be associated with the prognosis of cancer. The Geriatric Nutritional Risk Index (GNRI), based on serum albumin levels,…”
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Specific activation of glycolytic enzyme enolase 2 in BRAF V600E‐mutated colorectal cancer by Yukimoto, Ryohei, Nishida, Naohiro, Hata, Tsuyoshi, Fujino, Shiki, Ogino, Takayuki, Miyoshi, Norikatsu, Takahashi, Hidekazu, Uemura, Mamoru, Satoh, Taroh, Hirofumi, Yamamoto, Mizushima, Tsunekazu, Doki, Yuichiro, Eguchi, Hidetoshi

“…The BRAF V600E mutation occurs in approximately 10% of patients with metastatic colorectal cancer (CRC) and constitutes a distinct subtype of the disease with…”
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Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor by Iwamoto, Kazuya, Takahashi, Hidekazu, Okuzaki, Daisuke, Osawa, Hideo, Ogino, Takayuki, Miyoshi, Norikatsu, Uemura, Mamoru, Matsuda, Chu, Yamamoto, Hirofumi, Mizushima, Tsunekazu, Mori, Masaki, Doki, Yuichiro, Eguchi, Hidetoshi

“…Background The protein syntenin-1 is expressed by a variety of cell types, and is upregulated in various malignancies, including melanoma, breast cancer and…”
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HNF1A regulates colorectal cancer progression and drug resistance as a downstream of POU5F1 by Fujino, Shiki, Miyoshi, Norikatsu, Ito, Aya, Yasui, Masayoshi, Matsuda, Chu, Ohue, Masayuki, Uemura, Mamoru, Mizushima, Tsunekazu, Doki, Yuichiro, Eguchi, Hidetoshi

“…POU5F1-expressing cells can self-renew and differentiate, contributing to metastasis formation in colorectal cancer (CRC), but it plays an important role in…”
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Sarcopenia is associated with severe postoperative complications in elderly gastric cancer patients undergoing gastrectomy by Fukuda, Yasunari, Yamamoto, Kazuyoshi, Hirao, Motohiro, Nishikawa, Kazuhiro, Nagatsuma, Yukiko, Nakayama, Tamaki, Tanikawa, Sugano, Maeda, Sakae, Uemura, Mamoru, Miyake, Masakazu, Hama, Naoki, Miyamoto, Atsushi, Ikeda, Masataka, Nakamori, Shoji, Sekimoto, Mitsugu, Fujitani, Kazumasa, Tsujinaka, Toshimasa

“…Background Malignancy is a secondary cause of sarcopenia, which is associated with impaired cancer treatment outcomes. The aim of this study was to investigate…”
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SIRT3-Mediated SOD2 and PGC-1α Contribute to Chemoresistance in Colorectal Cancer Cells by Paku, Masakatsu, Haraguchi, Naotsugu, Takeda, Mitsunobu, Fujino, Shiki, Ogino, Takayuki, Takahashi, Hidekazu, Miyoshi, Norikatsu, Uemura, Mamoru, Mizushima, Tunekazu, Yamamoto, Hirofumi, Doki, Yuichiro, Eguchi, Hidetoshi

“…Background Anticancer drugs generate excessive reactive oxygen species (ROS), which can cause cell death. Cancer cells can resist this oxidative stress, but…”
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A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells by Takeda, Takashi, Yokoyama, Yuhki, Takahashi, Hidekazu, Okuzaki, Daisuke, Asai, Kaho, Itakura, Hiroaki, Miyoshi, Norikatsu, Kobayashi, Shogo, Uemura, Mamoru, Fujita, Toshitsugu, Ueno, Hiroo, Mori, Masaki, Doki, Yuichiro, Fujii, Hodaka, Eguchi, Hidetoshi, Yamamoto, Hirofumi

“…Background KLF5 plays a crucial role in stem cells of colorectum in cooperation with Lgr5 gene. In this study, we aimed to explicate a regulatory mechanism of…”
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Cold atmospheric plasma treatment selectively targets head and neck squamous cell carcinoma cells by GUERRERO-PRESTON, RAFAEL, OGAWA, TAKENORI, UEMURA, MAMORU, SHUMULINSKY, GARY, VALLE, BLANCA L, PIRINI, FRANCESCA, RAVI, RAJANI, SIDRANSKY, DAVID, KEIDAR, MICHAEL, TRINK, BARRY

“…The treatment of locoregional recurrence (LRR) of head and neck squamous cell carcinoma (HNSCC) often requires a combination of surgery, radiation therapy…”
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Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages by Yasueda, Asuka, Kayama, Hisako, Murohashi, Michiko, Nishimura, Junichi, Wakame, Koji, Komatsu, Ken-ichi, Ogino, Takayuki, Miyoshi, Norikatsu, Takahashi, Hidekazu, Uemura, Mamoru, Matsuda, Chu, Kitagawa, Toru, Takeda, Kiyoshi, Ito, Toshinori, Doki, Yuichiro, Eguchi, Hidetoshi, Shimizu, Shigeomi, Mizushima, Tsunekazu

“…Disturbed activation of autophagy is implicated in the pathogenesis of inflammatory bowel disease. Accordingly, several autophagy-related genes have been…”
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Prognostic Impact of Lateral Pelvic Node Dissection on the Survival of Patients in Low Rectal Cancer Subgroups Based on Lymph Node Size by Hida, Koya, Nishizaki, Daisuke, Sumii, Atsuhiko, Okamura, Ryosuke, Sakai, Yoshiharu, Konishi, Tsuyoshi, Akagi, Tomonori, Yamaguchi, Tomohiro, Akiyoshi, Takashi, Fukuda, Meiki, Yamamoto, Seiichiro, Arizono, Shigeki, Uemura, Mamoru, Hasegawa, Hirotoshi, Kawada, Kenji, Morita, Satoshi, Watanabe, Masahiko

“…Background Lateral pelvic node (LPN) dissection (LPND) is considered a promising technique for treating low rectal cancer; however, there is insufficient…”
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Three-dimensional anatomical structure formed by granule cell layer and pyramidal cell layer in human hippocampus by Kominami, Rieko, Sonomura, Takahiro, Ito, Tetsufumi, Shinohara, Harumichi, Kishibe, Miyuki, Uemura, Mamoru, Honma, Satoru

“…In the human hippocampus, the pyramidal layer consists of the inferior aspect of the hippocampus which is organized segmentally. Each segment, together with…”
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Detection of senescent cells in the mucosal healing process on type 2 diabetic rats after tooth extraction for biomaterial development by LUO, Chuyi, NAKAGAWA, Masato, SUMI, Yoichi, MATSUSHIMA, Yasuhiko, UEMURA, Mamoru, HONDA, Yoshitomo, MATSUMOTO, Naoyuki

“…The delayed mucosal healing of tooth extraction sockets in diabetes has few known effective treatment strategies, and its underlying mechanism remains unknown…”
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Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer by Ozato, Yuki, Kojima, Yasuhiro, Kobayashi, Yuta, Hisamatsu, Yuuichi, Toshima, Takeo, Yonemura, Yusuke, Masuda, Takaaki, Kagawa, Kouichi, Goto, Yasuhiro, Utou, Mitsuaki, Fukunaga, Mituko, Gamachi, Ayako, Imamura, Kiyomi, Kuze, Yuta, Zenkoh, Junko, Suzuki, Ayako, Niida, Atsushi, Hirose, Haruka, Hayashi, Shuto, Koseki, Jun, Oki, Eiji, Fukuchi, Satoshi, Murakami, Kazunari, Tobo, Taro, Nagayama, Satoshi, Uemura, Mamoru, Sakamoto, Takeharu, Oshima, Masanobu, Doki, Yuichiro, Eguchi, Hidetoshi, Mori, Masaki, Iwasaki, Takeshi, Oda, Yoshinao, Shibata, Tatsuhiro, Suzuki, Yutaka, Shimamura, Teppei, Mimori, Koshi

“…The cellular interactions in the tumor microenvironment of colorectal cancer (CRC) are poorly understood, hindering patient treatment. In the current study, we…”
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Comprehensive profiling of novel epithelial–mesenchymal transition mediators and their clinical significance in colorectal cancer by Ishikawa, Satoshi, Nishida, Naohiro, Fujino, Shiki, Ogino, Takayuki, Takahashi, Hidekazu, Miyoshi, Norikatsu, Uemura, Mamoru, Satoh, Taroh, Yamamoto, Hirofumi, Mizushima, Tsunekazu, Doki, Yuichiro, Eguchi, Hidetoshi

“…Epithelial–mesenchymal transition (EMT) is a drastic phenotypic change during cancer metastasis and is one of the most important hallmarks of aggressive…”
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Development of novel rectal/uterine clamping device by Urabe, Shoichiro, Hata, Taishi, Kobayashi, Eiji, Ishii, Yuji, Ushimaru, Yuki, Takeda, Mitsunobu, Sekido, Yuki, Hata, Tsuyoshi, Hamabe, Atsushi, Ogino, Takayuki, Miyoshi, Norikatsu, Uemura, Mamoru, Yamamoto, Hirofumi, Doki, Yuichiro, Eguchi, Hidetoshi, Nakajima, Kiyokazu

“…We developed a novel clamping device for laparoscopic surgery, free from conventional pinch structure, capable of uniformly occluding any ductal organ. This…”
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PLXND1/SEMA3E Promotes Epithelial–Mesenchymal Transition Partly via the PI3K/AKT-Signaling Pathway and Induces Heterogenity in Colorectal Cancer by Hagihara, Kiyotaka, Haraguchi, Naotsugu, Nishimura, Junichi, Yasueda, Asuka, Fujino, Shiki, Ogino, Takayuki, Takahashi, Hidekazu, Miyoshi, Norikatsu, Uemura, Mamoru, Matsuda, Chu, Mizushima, Tsunekazu, Yamamoto, Hirofumi, Mori, Masaki, Doki, Yuichiro, Eguchi, Hidetoshi

“…Colorectal cancer (CRC) is a major cause of cancer-related deaths. Metastasis is enhanced through epithelial-mesenchymal transition (EMT), a process primarily…”
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The prediction of postoperative anorectal dysfunction after low anterior resection for lower rectal cancer by measuring the volume of defecation-related muscles by Mori, Ryota, Uemura, Mamoru, Tsuboyama, Takahiro, Fujino, Shiki, Hata, Tsuyoshi, Ogino, Takayuki, Takahashi, Hidekazu, Miyoshi, Norikatsu, Mizushima, Tsunekazu, Doki, Yuichiro, Eguchi, Hidetoshi

“…Purpose Approximately 90% of patients are thought to develop bowel dysfunction after low anterior resection (LAR). Although some prognostic factors have been…”
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Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis by Kawai, Kenji, Uemura, Mamoru, Munakata, Koji, Takahashi, Hidekazu, Haraguchi, Naotsugu, Nishimura, Junichi, Hata, Taishi, Matsuda, Chu, Ikenaga, Masakazu, Murata, Kohei, Mizushima, Tsunekazu, Yamamoto, Hirofumi, Doki, Yuichiro, Mori, Masaki

“…Hypoxia is an essential feature of cancer malignancy, but there are no methods for the routine detection of hypoxia-inducible prognostic factors and potential…”
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Low G9a expression is a tumor progression factor of colorectal cancer via IL-8 promotion by Ichikawa, Yoshitoshi, Takahashi, Hidekazu, Chinen, Yoshinao, Arita, Asami, Sekido, Yuki, Hata, Tsuyoshi, Ogino, Takayuki, Miyoshi, Norikatsu, Uemura, Mamoru, Yamamoto, Hirofumi, Mizushima, Tsunekazu, Doki, Yuichiro, Eguchi, Hidetoshi

“…Abstract The histone methyltransferase G9a is expressed in various types of cancer cells, including colorectal cancer (CRC) cells. Interleukin 8 (IL)-8, also…”
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The meiosis-specific cohesin component stromal antigen 3 promotes cell migration and chemotherapeutic resistance in colorectal cancer by Sasaki, Masaru, Miyoshi, Norikatsu, Fujino, Shiki, Saso, Kazuhiro, Ogino, Takayuki, Takahashi, Hidekazu, Uemura, Mamoru, Yamamoto, Hirofumi, Matsuda, Chu, Yasui, Masayoshi, Ohue, Masayuki, Mizushima, Tsunekazu, Doki, Yuichiro, Eguchi, Hidetoshi

“…Chromosome instability is one of the hallmarks of cancer. Stromal antigen (STAG) 3 is a core component of the meiosis-specific cohesin complex, which regulates…”
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