Search Results - "Uemi, Miriam"
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1
Selenium species-catalyzed biomimetic halogenations of aromatic and heteroaromatic compounds
Published in Chemical papers (01-08-2024)“…Herein, we report our investigations on the biomimetic bromofunctionalization of aromatic and heteroaromatic compounds using NaBr as a source of bromine, 30%…”
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2
Structure-activity relationship study of antitrypanosomal chalcone derivatives using multivariate analysis
Published in Bioorganic & medicinal chemistry letters (15-06-2019)“…[Display omitted] Chagas disease represents one of several neglected diseases with a reduced number of chemotherapeutical drugs including the highly toxic…”
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3
Chemodiversity and Anti-Leukemia Effect of Metabolites from Penicillium setosum CMLD 18
Published in Metabolites (23-12-2022)“…represents a species recently described, with little up-to-date information about its metabolic and biological potential. Due to this scenario, we performed…”
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4
Antileishmanial Activity and Immunomodulatory Effects of Tricin Isolated from Leaves of Casearia arborea (Salicaceae)
Published in Chemistry & biodiversity (01-05-2017)“…Bioactivity‐guided fractionation of antileishmanial active extract from leaves of Casearia arborea led to isolation of three metabolites: tricin (1),…”
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5
Biological hydroperoxides and singlet molecular oxygen generation
Published in IUBMB life (2007)“…The decomposition of lipid hydroperoxides (LOOH) into peroxyl radicals is a potential source of singlet molecular oxygen (1O2) in biological systems. Recently,…”
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6
Highly Sensitive Fluorescent Method for the Detection of Cholesterol Aldehydes Formed by Ozone and Singlet Molecular Oxygen
Published in Analytical chemistry (Washington) (15-08-2010)“…Cholesterol oxidation gives rise to a mixture of oxidized products. Different types of products are generated according to the reactive species being involved…”
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7
Characterization of oxyphytosterols generated by β-sitosterol ozonization
Published in Archives of biochemistry and biophysics (15-08-2020)“…β-Sitosterol (βSito) is the most abundant phytosterol found in elevated concentrations in vegetable oils, nuts, seeds, cereals, fruits, and in many…”
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8
Antitrypanosomal activity of new alkoxyhydroperoxides formed by cycloaddition of ozone into allyl moiety of eugenol
Published in Tetrahedron (15-06-2024)“…Eugenol, a natural phenylpropanoid found in several plants, was exposed to ozone atmosphere to afford three new alkoxyhydroperoxides and prevised homovanillin…”
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Niobium chloride in 1−n−butyl−3−methylimidazolium chloride ionic liquid as a catalyst for biginelli reaction
Published in Journal of molecular structure (15-11-2020)“…In this study, NbCl5 in a liquid ionic medium was evaluated as a catalyst for Biginelli reaction. Firstly, the ionic species found in mixtures of NbCl5 and…”
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10
Biological effects of an oxyphytosterol generated by β-Sitosterol ozonization
Published in Archives of biochemistry and biophysics (15-12-2020)“…β-Sitosterol (βSito) is the most abundant phytosterol found in vegetable oils, grains such as wheat, beans, and corn, and in many phytosterol-enriched foods…”
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11
Cytotoxic effects of neolignans from Saururus cernuus (Saururaceae) against prostate cancer cells
Published in Chemical biology & drug design (01-06-2023)“…In this study, five neolignans were isolated from Saururus cernuus—threo‐dihydroguaiaretic acid (1), threo‐austrobailignan‐6 (2), threo‐austrobailignan‐5 (3),…”
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12
Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata
Published in Experimental parasitology (01-03-2017)“…The development of novel drugs for the treatment of leishmaniases continues to be crucial to overcome the severe impacts of these diseases on human and animal…”
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13
Antitrypanosomal activity and evaluation of the mechanism of action of dehydrodieugenol isolated from Nectandra leucantha (Lauraceae) and its methylated derivative against Trypanosoma cruzi
Published in Phytomedicine (Stuttgart) (15-01-2017)“…From a previous screening of Brazilian biodiversity for antiprotozoal activity, the hexane extract from leaves of Nectandra leucantha (Nees & Mart.)…”
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14
Molecular network for accessing polyketide derivatives from Phomopsis sp., an endophytic fungus of Casearia arborea (Salicaceae)
Published in Phytochemistry letters (01-04-2021)“…[Display omitted] •Casearia genus has chemistry from the plant microbiota still unknown.•The endophytic fungus Phomopsis sp. was isolated from leaves of C…”
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15
Generation of Cholesterol Carboxyaldehyde by the Reaction of Singlet Molecular Oxygen [O2 (1Δg)] as Well as Ozone with Cholesterol
Published in Chemical research in toxicology (18-05-2009)“…A few years ago, it was reported that ozone is produced in human atherosclerotic arteries, on the basis of the identification of…”
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16
Report of in vitro antileishmanial properties of Iberian macroalgae
Published in Natural product research (18-06-2019)“…Here is reported the anti Leishmania infantum activity of 48 hexane, CH 2 Cl 2 and MeOH extracts from 16 macroalgae collected on the Iberian Coast. Seven…”
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17
Cholesterol Hydroperoxides Generate Singlet Molecular Oxygen [O2 (1Δg)]: Near-IR Emission, 18O-Labeled Hydroperoxides, and Mass Spectrometry
Published in Chemical research in toxicology (20-06-2011)“…In mammalian membranes, cholesterol is concentrated in lipid rafts. The generation of cholesterol hydroperoxides (ChOOHs) and their decomposition products…”
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Cholesterol hydroperoxides generate singlet molecular oxygen [O(2) ((1)Δ(g))]: near-IR emission, (18)O-labeled hydroperoxides, and mass spectrometry
Published in Chemical research in toxicology (20-06-2011)“…In mammalian membranes, cholesterol is concentrated in lipid rafts. The generation of cholesterol hydroperoxides (ChOOHs) and their decomposition products…”
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19
Study of the Complexation of Fisetin with Cyclodextrins
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (14-09-2006)“…In this work, the interaction between fisetin (3,3‘,4‘,7-tetrahydroxyflavone) (Fis) and cyclodextrins (CDs) (α and β) was studied through UV−vis absorption,…”
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20
Integrated workflows using metabolomics, genome mining, and biological evaluation reveal oxepine‑sulfur-containing anti-cryptococcal diketopiperazine produced by the endophyte Penicillium setosum
Published in Fitoterapia (16-11-2024)“…Cryptococcosis is a fungal infection for which treatment relies on old antifungal agents usually leading to drawbacks such as high toxicity and mainly low…”
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