Search Results - "Ueki, Hiroshi"

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development by Imai, Masaki, Iwatsuki-Horimoto, Kiyoko, Hatta, Masato, Loeber, Samantha, Halfmann, Peter J., Nakajima, Noriko, Watanabe, Tokiko, Ujie, Michiko, Takahashi, Kenta, Ito, Mutsumi, Yamada, Shinya, Fan, Shufang, Chiba, Shiho, Kuroda, Makoto, Guan, Lizheng, Takada, Kosuke, Armbrust, Tammy, Balogh, Aaron, Furusawa, Yuri, Okuda, Moe, Ueki, Hiroshi, Yasuhara, Atsuhiro, Sakai-Tagawa, Yuko, Lopes, Tiago J. S., Kiso, Maki, Yamayoshi, Seiya, Kinoshita, Noriko, Ohmagari, Norio, Hattori, Shin-ichiro, Takeda, Makoto, Mitsuya, Hiroaki, Krammer, Florian, Suzuki, Tadaki, Kawaoka, Yoshihiro

“…At the end of 2019, a novel coronavirus (severe acute respiratory syndrome coronavirus 2; SARS-CoV-2) was detected in Wuhan, China, that spread rapidly around…”
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Effectiveness of Face Masks in Preventing Airborne Transmission of SARS-CoV-2 by Ueki, Hiroshi, Furusawa, Yuri, Iwatsuki-Horimoto, Kiyoko, Imai, Masaki, Kabata, Hiroki, Nishimura, Hidekazu, Kawaoka, Yoshihiro

“…Guidelines from the CDC and the WHO recommend the wearing of face masks to prevent the spread of coronavirus (CoV) disease 2019 (COVID-19); however, the…”
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Characterization of SARS-CoV-2 Omicron BA.4 and BA.5 isolates in rodents by Uraki, Ryuta, Halfmann, Peter J., Iida, Shun, Yamayoshi, Seiya, Furusawa, Yuri, Kiso, Maki, Ito, Mutsumi, Iwatsuki-Horimoto, Kiyoko, Mine, Sohtaro, Kuroda, Makoto, Maemura, Tadashi, Sakai-Tagawa, Yuko, Ueki, Hiroshi, Li, Rong, Liu, Yanan, Larson, Deanna, Fukushi, Shuetsu, Watanabe, Shinji, Maeda, Ken, Pekosz, Andrew, Kandeil, Ahmed, Webby, Richard J., Wang, Zhongde, Imai, Masaki, Suzuki, Tadaki, Kawaoka, Yoshihiro

“…The BA.2 sublineage of the SARS-CoV-2 Omicron variant has become dominant in most countries around the world; however, the prevalence of BA.4 and BA.5 is…”
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Multicolor two-photon imaging of in vivo cellular pathophysiology upon influenza virus infection using the two-photon IMPRESS by Ueki, Hiroshi, Wang, I-Hsuan, Zhao, Dongming, Gunzer, Matthias, Kawaoka, Yoshihiro

“…In vivo two-photon imaging is a valuable technique for studies of viral pathogenesis and host responses to infection in vivo. In this protocol, we describe a…”
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Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses by Chiba, Shiho, Ikushima, Hiroaki, Ueki, Hiroshi, Yanai, Hideyuki, Kimura, Yoshitaka, Hangai, Sho, Nishio, Junko, Negishi, Hideo, Tamura, Tomohiko, Saijo, Shinobu, Iwakura, Yoichiro, Taniguchi, Tadatsugu

“…The eradication of tumor cells requires communication to and signaling by cells of the immune system. Natural killer (NK) cells are essential tumor-killing…”
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In vivo imaging of the pathophysiological changes and neutrophil dynamics in influenza virus-infected mouse lungs by Ueki, Hiroshi, Wang, I-Hsuan, Fukuyama, Satoshi, Katsura, Hiroaki, da Silva Lopes, Tiago Jose, Neumann, Gabriele, Kawaoka, Yoshihiro

“…The pathophysiological changes that occur in lungs infected with influenza viruses are poorly understood. Here we established an in vivo imaging system that…”
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Development of a Mouse-Adapted Reporter SARS-CoV-2 as a Tool for Two-Photon In Vivo Imaging by Ueki, Hiroshi, Kiso, Maki, Furusawa, Yuri, Iida, Shun, Yamayoshi, Seiya, Nakajima, Noriko, Imai, Masaki, Suzuki, Tadaki, Kawaoka, Yoshihiro

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) often causes severe viral pneumonia. Although many studies using mouse models have examined the…”
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Characterization of SARS-CoV-2 Omicron BA.2.75 clinical isolates by Uraki, Ryuta, Iida, Shun, Halfmann, Peter J., Yamayoshi, Seiya, Hirata, Yuichiro, Iwatsuki-Horimoto, Kiyoko, Kiso, Maki, Ito, Mutsumi, Furusawa, Yuri, Ueki, Hiroshi, Sakai-Tagawa, Yuko, Kuroda, Makoto, Maemura, Tadashi, Kim, Taksoo, Mine, Sohtaro, Iwamoto, Noriko, Li, Rong, Liu, Yanan, Larson, Deanna, Fukushi, Shuetsu, Watanabe, Shinji, Maeda, Ken, Wang, Zhongde, Ohmagari, Norio, Theiler, James, Fischer, Will, Korber, Bette, Imai, Masaki, Suzuki, Tadaki, Kawaoka, Yoshihiro

“…The prevalence of the Omicron subvariant BA.2.75 rapidly increased in India and Nepal during the summer of 2022, and spread globally. However, the virological…”
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A 265-Nanometer High-Power Deep-UV Light-Emitting Diode Rapidly Inactivates SARS-CoV-2 Aerosols by Ueki, Hiroshi, Ito, Mutsumi, Furusawa, Yuri, Yamayoshi, Seiya, Inoue, Shin-Ichiro, Kawaoka, Yoshihiro

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) is an acute respiratory infection transmitted by droplets, aerosols, and…”
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Effectiveness of HEPA Filters at Removing Infectious SARS-CoV-2 from the Air by Ueki, Hiroshi, Ujie, Michiko, Komori, Yosuke, Kato, Tatsuo, Imai, Masaki, Kawaoka, Yoshihiro

“…Coronavirus disease 2019 (COVID-19) spreads by airborne transmission; therefore, the development and functional evaluation of air-cleaning technologies are…”
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Characterization of Omicron BA.4.6, XBB, and BQ.1.1 subvariants in hamsters by Halfmann, Peter J., Iwatsuki-Horimoto, Kiyoko, Kuroda, Makoto, Hirata, Yuichiro, Yamayoshi, Seiya, Iida, Shun, Uraki, Ryuta, Ito, Mutsumi, Ueki, Hiroshi, Furusawa, Yuri, Sakai-Tagawa, Yuko, Kiso, Maki, Armbrust, Tammy, Spyra, Sam, Maeda, Ken, Wang, Zhongde, Imai, Masaki, Suzuki, Tadaki, Kawaoka, Yoshihiro

“…During the Omicron wave, previous variants such as BA.2, BA.4, and BA.5 were replaced by newer variants with additional mutations in the spike protein. These…”
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Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models by Takeshita, Masaru, Fukuyama, Hidehiro, Kamada, Katsuhiko, Matsumoto, Takehisa, Makino-Okamura, Chieko, Uchikubo-Kamo, Tomomi, Tomabechi, Yuri, Hanada, Kazuharu, Moriyama, Saya, Takahashi, Yoshimasa, Ishigaki, Hirohito, Nakayama, Misako, Nguyen, Cong Thanh, Kitagawa, Yoshinori, Itoh, Yasushi, Imai, Masaki, Maemura, Tadashi, Furusawa, Yuri, Ueki, Hiroshi, Iwatsuki-Horimoto, Kiyoko, Ito, Mutsumi, Yamayoshi, Seiya, Kawaoka, Yoshihiro, Shirouzu, Mikako, Ishii, Makoto, Saya, Hideyuki, Kondo, Yasushi, Kaneko, Yuko, Suzuki, Katsuya, Fukunaga, Koichi, Takeuchi, Tsutomu

“…The use of therapeutic neutralizing antibodies against SARS-CoV-2 infection has been highly effective. However, there remain few practical antibodies against…”
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SARS-CoV-2 Transmission from Virus-Infected Dead Hamsters by Iwatsuki-Horimoto, Kiyoko, Ueki, Hiroshi, Ito, Mutsumi, Nagasawa, Sayaka, Hirata, Yuichiro, Hashizume, Kenichiro, Ushiwata, Kazuho, Iwase, Hirotaro, Makino, Yohsuke, Ushiku, Tetsuo, Akitomi, Shinji, Imai, Masaki, Saitoh, Hisako, Kawaoka, Yoshihiro

“…Although it has been 2.5 years since the coronavirus disease 2019 (COVID-19) pandemic began, the transmissibility of severe acute respiratory syndrome…”
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Effect of Orthovanadate on Platelet Aggregation Induced by Platelet-Activating Factor by Suenaga, Aya, Ueki, Hiroshi

“…Orthovanadate (vanadate) inhibited the platelet aggregation induced by platelet-activating factor (PAF) in a dose-dependent manner. Propranolol, a nonspecific…”
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Humoral immune evasion of the omicron subvariants BQ.1.1 and XBB by Uraki, Ryuta, Ito, Mutsumi, Furusawa, Yuri, Yamayoshi, Seiya, Iwatsuki-Horimoto, Kiyoko, Adachi, Eisuke, Saito, Makoto, Koga, Michiko, Tsutsumi, Takeya, Yamamoto, Shinya, Otani, Amato, Kiso, Maki, Sakai-Tagawa, Yuko, Ueki, Hiroshi, Yotsuyanagi, Hiroshi, Imai, Masaki, Kawaoka, Yoshihiro

“…BQ.1.1 and XBB possess substitutions relative to BA.5 and BA.2, respectively, in the receptor-binding domain of their spike protein (appendix p 4), which is…”
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Orthovanadate Stimulates cAMP Phosphodiesterase 3 Activity in Isolated Rat Hepatocytes through Mitogen-Activated Protein Kinase Activation Dependent on cAMP-Dependent Protein Kinase by Watanabe, Tomoyasu, Satoo, Hirofumi, Kohara, Kazuhisa, Takami, Reiko, Motoyashiki, Toshio, Morita, Tetsuo, Ueki, Hiroshi

“…Orthovanadate (vanadate) as well as insulin stimulated phosphodiesterase 3 (PDE3) in the particulate fraction of rat hepatocytes. The vanadate-induced…”
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SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters by Halfmann, Peter J., Iida, Shun, Iwatsuki-Horimoto, Kiyoko, Maemura, Tadashi, Kiso, Maki, Scheaffer, Suzanne M., Darling, Tamarand L., Joshi, Astha, Loeber, Samantha, Singh, Gagandeep, Foster, Stephanie L., Ying, Baoling, Case, James Brett, Chong, Zhenlu, Whitener, Bradley, Moliva, Juan, Floyd, Katharine, Ujie, Michiko, Nakajima, Noriko, Ito, Mutsumi, Wright, Ryan, Uraki, Ryuta, Warang, Prajakta, Gagne, Matthew, Li, Rong, Sakai-Tagawa, Yuko, Liu, Yanan, Larson, Deanna, Osorio, Jorge E., Hernandez-Ortiz, Juan P., Henry, Amy R., Ciuoderis, Karl, Florek, Kelsey R., Patel, Mit, Odle, Abby, Wong, Lok-Yin Roy, Bateman, Allen C., Wang, Zhongde, Edara, Venkata-Viswanadh, Franks, John, Jeevan, Trushar, Fabrizio, Thomas, DeBeauchamp, Jennifer, Kercher, Lisa, Seiler, Patrick, Gonzalez-Reiche, Ana Silvia, Sordillo, Emilia Mia, Chang, Lauren A., van Bakel, Harm, Simon, Viviana, Douek, Daniel C., Sullivan, Nancy J., Thackray, Larissa B., Ueki, Hiroshi, Yamayoshi, Seiya, Imai, Masaki, Perlman, Stanley, Webby, Richard J., Seder, Robert A., Suthar, Mehul S., García-Sastre, Adolfo, Schotsaert, Michael, Suzuki, Tadaki, Boon, Adrianus C. M., Diamond, Michael S., Kawaoka, Yoshihiro

“…The recent emergence of B.1.1.529, the Omicron variant 1 , 2 , has raised concerns of escape from protection by vaccines and therapeutic antibodies. A key test…”
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Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA.2 by Uraki, Ryuta, Kiso, Maki, Iida, Shun, Imai, Masaki, Takashita, Emi, Kuroda, Makoto, Halfmann, Peter J., Loeber, Samantha, Maemura, Tadashi, Yamayoshi, Seiya, Fujisaki, Seiichiro, Wang, Zhongde, Ito, Mutsumi, Ujie, Michiko, Iwatsuki-Horimoto, Kiyoko, Furusawa, Yuri, Wright, Ryan, Chong, Zhenlu, Ozono, Seiya, Yasuhara, Atsuhiro, Ueki, Hiroshi, Sakai-Tagawa, Yuko, Li, Rong, Liu, Yanan, Larson, Deanna, Koga, Michiko, Tsutsumi, Takeya, Adachi, Eisuke, Saito, Makoto, Yamamoto, Shinya, Hagihara, Masao, Mitamura, Keiko, Sato, Tetsuro, Hojo, Masayuki, Hattori, Shin-ichiro, Maeda, Kenji, Valdez, Riccardo, Okuda, Moe, Murakami, Jurika, Duong, Calvin, Godbole, Sucheta, Douek, Daniel C., Maeda, Ken, Watanabe, Shinji, Gordon, Aubree, Ohmagari, Norio, Yotsuyanagi, Hiroshi, Diamond, Michael S., Hasegawa, Hideki, Mitsuya, Hiroaki, Suzuki, Tadaki, Kawaoka, Yoshihiro

“…The recent emergence of SARS-CoV-2 Omicron (B.1.1.529 lineage) variants possessing numerous mutations has raised concerns of decreased effectiveness of current…”
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Isolation of New Isoflavonolignans, Butesuperins A and B, from a Thai Miracle Herb, Butea superba by Ishikawa, Tsutomu, Ma, Kai, Seki, Hiroko, Furihata, Kazuo, Ueki, Hiroshi, Narimatsu, Shizuo, Higuchi, Yoshihiro, Chaichantipyuth, Chaiyo

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Okadaic Acid Decreases the Leptin Content in Isolated Mouse Fat Pads by Mitsuishi, Hiroko, Yoshida, Aya, Motoyashiki, Toshio, Morita, Tetsuo, Ueki, Hiroshi

“…Okadaic acid (OA) decreased the leptin content in isolated mouse fat pads in a time and dose-dependent manner. MG-132, a membrane-permeable proteasome…”
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