Search Results - "Ueda, Kumiko"
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Effects of Decitabine on Invasion and Exosomal Expression of miR-200c and miR-141 in Oxaliplatin-Resistant Colorectal Cancer Cells
Published in Biological & pharmaceutical bulletin (01-09-2015)“…The effects of decitabine (DAC), a DNA methyltransferase (DNMT) inhibitor, on metastasis and exosomal expression of microRNAs were examined in SW620/OxR cells,…”
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Induction of Epithelial-Mesenchymal Transition and Down-Regulation of miR-200c and miR-141 in Oxaliplatin-Resistant Colorectal Cancer Cells
Published in Biological & pharmaceutical bulletin (01-03-2015)“…Epithelial-mesenchymal transition (EMT) and changes in the expression of the microRNA-200 (miR-200) family were examined in the human colorectal cancer (CRC)…”
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Cellular Uptake of Decitabine by Equilibrative Nucleoside Transporters in HCT116 Cells
Published in Biological & pharmaceutical bulletin (01-08-2015)“…DNA hypermethylation, an epigenetic change that silences gene expression without altering nucleotide sequences, plays a critical role in the formation and…”
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Optimization of Analytical Conditions for Hydrophilic Nucleic Acids Using Mixed-Mode and Reversed-Phase Pentabromobenzyl Columns
Published in Chemical & pharmaceutical bulletin (01-12-2020)“…The aim of this study was to investigate appropriate analytical conditions for hydrophilic nucleosides and nucleotides (monophosphates and triphosphates) by…”
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Different Effects of Epigenetic Modifiers on the Cytotoxicity Induced by 5-Fluorouracil, Irinotecan or Oxaliplatin in Colon Cancer Cells
Published in Biological & pharmaceutical bulletin (01-01-2014)“…We investigated the effects of epigenetic modifiers such as DNA methyltransferase (DNMT) or histone deacetylase (HDAC) inhibitors on the cytotoxicity induced…”
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Clinicopathological and molecular characterization of early gastric adenocarcinoma in Helicobacter pylori-uninfected patients: emphasis on differentiated gastric adenocarcinoma
Published in Journal of gastroenterology (01-10-2022)“…Background Recently, Helicobacter pylori (HP) -uninfected gastric mucosal cancer has been reported; however, the clinicopathological and molecular features of…”
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Effects of Zebularine on Invasion Activity and Intracellular Expression Level of let-7b in Colorectal Cancer Cells
Published in Biological & pharmaceutical bulletin (01-08-2017)“…The effects of zebularine, a DNA methyltransferase inhibitor, on the invasion activity as well as intracellular expression level of let-7b, tumor suppressor…”
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Different Schedule-Dependent Effects of Epigenetic Modifiers on Cytotoxicity by Anticancer Drugs in Colorectal Cancer Cells
Published in Biological & pharmaceutical bulletin (01-12-2017)“…Limited information is currently available on how to apply epigenetic modifiers to current colorectal cancer (CRC) chemotherapy. The purpose of this study is…”
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Yersinia enterocolitica Enteritis Diagnosed with Erythema Nodosum
Published in Internal Medicine (15-05-2023)“…We herein report a rare case of Yersinia enterocolitica enteritis with a fever and abdominal pain followed by erythema nodosum (EN) a few days later. The…”
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Mediastinal Thoracic Duct Cyst Infection after Endoscopic Submucosal Dissection for Early Esophageal Cancer
Published in Internal Medicine (01-07-2023)“…A mediastinal thoracic duct cyst that originates from the thoracic duct is a very rare disease in the mediastinum. There have been no reports of mediastinal…”
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Different Involvement of DNA Methylation and Histone Deacetylation in the Expression of Solute-Carrier Transporters in 4 Colon Cancer Cell Lines
Published in Biological & pharmaceutical bulletin (2012)“…The purpose of this study on the involvement of epigenetic control of the expression of solute carrier (SLC) transporters by DNA methylation and histone…”
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Different Schedule-Dependent Effects of Epigenetic Modifiers on Cytotoxicity by Anticancer Drugs in Colorectal Cancer Cells
Published in Biological and Pharmaceutical Bulletin (01-12-2017)“…Limited information is currently available on how to apply epigenetic modifiers to current colorectal cancer (CRC) chemotherapy. The purpose of this study is…”
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Initiation of a Helicobacter pylori Screening Program: Enhancing Healthcare at Juntendo University
Published in Juntendo Iji Zasshi = Juntendo Medical Journal (2024)“…Objectives We started Helicobacter pylori (H. pylori) screening program of students at Juntendo university in 2020. We report the current status of H. pylori…”
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Numerical analysis of apparent decitabine uptake in HCT116 cells: Incorporation of a bidirectional first-order kinetic parameter for ENT1 transport and Michaelis-Menten parameters for subsequent phosphorylation
Published in Drug metabolism and pharmacokinetics (01-02-2020)“…Decitabine (DAC), a DNA methylation inhibitor, is transported into cancer cells mainly via equilibrative nucleoside transporter 1 (ENT1) and subsequently…”
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Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells
Published in Drug metabolism and pharmacokinetics (01-12-2017)“…Decitabine (DAC), a nucleoside-related DNA methylation inhibitor, is taken up into cancer cells via equilibrative nucleoside transporter 1 (ENT1), and is then…”
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Gastric Juvenile Polyposis with Intramucosal Cancer Diagnosed by Magnifying Endoscopy with Narrow-band Imaging
Published in Internal Medicine (15-11-2023)“…Although gastric juvenile polyposis (GJP) often coexists with gastric cancer, a preoperative accurate diagnosis is still difficult to obtain. A 70-year-old…”
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A Magnesium Oxide Bezoar
Published in Internal Medicine (01-11-2018)“…A 75-year-old Japanese woman presented with nausea and appetite loss. Computed tomography showed a radiopaque substance in the stomach…”
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Linked color imaging improves visibility of reflux esophagitis
Published in BMC gastroenterology (27-10-2020)“…With more prevalent gastroesophageal reflux disease comes increased cases of Barrett's esophagus and esophageal adenocarcinoma. Image-enhanced endoscopy using…”
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The relationship between Helicobacter pylori infection and reflux esophagitis and the long-term effects of eradication of Helicobacter pylori on reflux esophagitis
Published in Therapeutic advances in gastroenterology (2021)“…Introduction: Whether the incidence of reflux esophagitis (RE) increases after the eradication of Helicobacter pylori (H. pylori) is controversial. Few reports…”
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