Search Results - "Ueda, Kazuto"

Intravenously delivered multilineage-differentiating stress enduring cells dampen excessive glutamate metabolism and microglial activation in experimental perinatal hypoxic ischemic encephalopathy by Suzuki, Toshihiko, Sato, Yoshiaki, Kushida, Yoshihiro, Tsuji, Masahiro, Wakao, Shohei, Ueda, Kazuto, Imai, Kenji, Iitani, Yukako, Shimizu, Shinobu, Hida, Hideki, Temma, Takashi, Saito, Shigeyoshi, Iida, Hidehiro, Mizuno, Masaaki, Takahashi, Yoshiyuki, Dezawa, Mari, Borlongan, Cesar V, Hayakawa, Masahiro

“…Perinatal hypoxic ischemic encephalopathy (HIE) results in serious neurological dysfunction and mortality. Clinical trials of multilineage-differentiating…”
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Dedifferentiated fat cells administration ameliorates abnormal expressions of fatty acids metabolism-related protein expressions and intestinal tissue damage in experimental necrotizing enterocolitis by Mimatsu, Haruka, Onoda, Atsuto, Kazama, Tomohiko, Nishijima, Koji, Shimoyama, Yoshie, Go, Shoji, Ueda, Kazuto, Takahashi, Yoshiyuki, Matsumoto, Taro, Hayakawa, Masahiro, Sato, Yoshiaki

“…Neonatal necrotizing enterocolitis (NEC) is a serious disease of premature infants that necessitates intensive care and frequently results in life-threatening…”
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Fetal growth restriction followed by early catch-up growth impairs pancreatic islet morphology in male rats by Jabary, Mahboba, Onoda, Atsuto, Kitase, Yuma, Ueda, Kazuto, Mimatsu, Haruka, Go, Shoji, Miura, Ryosuke, Tsuji, Masahiro, Takahashi, Yoshiyuki, Hayakawa, Masahiro, Sato, Yoshiaki

“…Fetal growth restriction (FGR), followed by postnatal early catch-up growth, is associated with an increased risk of metabolic dysfunction, including type 2…”
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Systemic administration of clinical-grade multilineage-differentiating stress-enduring cells ameliorates hypoxic–ischemic brain injury in neonatal rats by Ueda, Kazuto, Sato, Yoshiaki, Shimizu, Shinobu, Suzuki, Toshihiko, Onoda, Atsuto, Miura, Ryosuke, Go, Shoji, Mimatsu, Haruka, Kitase, Yuma, Yamashita, Yuta, Irie, Keiichi, Tsuji, Masahiro, Mishima, Kenichi, Mizuno, Masaaki, Takahashi, Yoshiyuki, Dezawa, Mari, Hayakawa, Masahiro

“…Multilineage-differentiating stress-enduring (Muse) cells are endogenous reparative pluripotent stem cells present in the bone marrow, peripheral blood, and…”
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TREC/KREC Newborn Screening followed by Next-Generation Sequencing for Severe Combined Immunodeficiency in Japan by Wakamatsu, Manabu, Kojima, Daiei, Muramatsu, Hideki, Okuno, Yusuke, Kataoka, Shinsuke, Nakamura, Fumiko, Sakai, Yoshimi, Tsuge, Ikuya, Ito, Tsuyoshi, Ueda, Kazuto, Saito, Akiko, Morihana, Eiji, Ito, Yasuhiko, Ohashi, Naoki, Tanaka, Makito, Tanaka, Taihei, Kojima, Seiji, Nakajima, Yoko, Ito, Tetsuya, Takahashi, Yoshiyuki

“…Purpose The aim of this study is to evaluate the usefulness of T cell receptor excision circle (TREC) and/or kappa-deleting recombination excision circle…”
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Findings of amplitude-integrated electroencephalogram recordings and serum vitamin B6 metabolites in perinatal lethal hypophosphatasia during enzyme replacement therapy by Ishiguro, Tomonori, Sugiyama, Yuichiro, Ueda, Kazuto, Muramatsu, Yukako, Tsuda, Hiroyuki, Kotani, Tomomi, Michigami, Toshimi, Tachikawa, Kanako, Akiyama, Tomoyuki, Hayakawa, Masahiro

“…Hypophosphatasia (HPP) is a rare disorder caused by low serum tissue non-specific alkaline phosphatase (ALP) activity due to hypomorphic mutations in the ALPL…”
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Safety and tolerability of a multilineage-differentiating stress-enduring cell-based product in neonatal hypoxic-ischaemic encephalopathy with therapeutic hypothermia (SHIELD trial): a clinical trial protocol open-label, non-randomised, dose-escalation trial by Matsuyama, Nao, Shimizu, Shinobu, Ueda, Kazuto, Suzuki, Toshihiko, Suzuki, Sakiko, Miura, Ryosuke, Katayama, Akemi, Ando, Masahiko, Mizuno, Masaaki, Hirakawa, Akihiro, Hayakawa, Masahiro, Sato, Yoshiaki

“…IntroductionNeonatal hypoxic-ischaemic encephalopathy (HIE) is an important illness associated with death or cerebral palsy. This study aims to assess the…”
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Delayed recognition of childhood arterial ischemic stroke by Hori, Ikumi, Tsuji, Takeshi, Miyake, Misa, Ueda, Kazuto, Kataoka, Erina, Suzuki, Michio, Kobayashi, Satoru, Kurahashi, Hirokazu, Takahashi, Yoshiyuki, Okumura, Akihisa, Yoshikawa, Tetsushi, Saitoh, Shinji, Natsume, Jun

“…Background Few population‐based surveys of childhood arterial ischemic stroke (AIS) have been conducted in Asian countries. The aim of this study was to…”
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Establishment of a Novel Fetal Growth Restriction Model and Development of a Stem-Cell Therapy Using Umbilical Cord-Derived Mesenchymal Stromal Cells by Kitase, Yuma, Sato, Yoshiaki, Arai, Sakiko, Onoda, Atsuto, Ueda, Kazuto, Go, Shoji, Mimatsu, Haruka, Jabary, Mahboba, Suzuki, Toshihiko, Ito, Miharu, Saito, Akiko, Hirakawa, Akihiro, Mukai, Takeo, Nagamura-Inoue, Tokiko, Takahashi, Yoshiyuki, Tsuji, Masahiro, Hayakawa, Masahiro

“…Fetal growth restriction (FGR) is a major complication of prenatal ischemic/hypoxic exposure and affects 5%–10% of pregnancies. It causes various disorders,…”
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Altered offspring neurodevelopment in an L-NAME-induced preeclampsia rat model by Nakamura, Noriyuki, Ushida, Takafumi, Onoda, Atsuto, Ueda, Kazuto, Miura, Ryosuke, Suzuki, Toshihiko, Katsuki, Satoru, Mizutani, Hidesuke, Yoshida, Kosuke, Tano, Sho, Iitani, Yukako, Imai, Kenji, Hayakawa, Masahiro, Kajiyama, Hiroaki, Sato, Yoshiaki, Kotani, Tomomi

“…To investigate the mechanism underlying the increased risk of subsequent neurodevelopmental disorders in children born to mothers with preeclampsia, we…”
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Impact of the Coronavirus Disease 2019 Pandemic on the Clinical Features of Pediatric Respiratory Syncytial Virus Infection in Japan by Ozeki, Shoko, Kawada, Jun-ichi, Yamashita, Daiki, Yasufuku, Chika, Akano, Takuya, Kato, Masahiro, Suzuki, Konomi, Tano, Chihiro, Matsumoto, Kazuki, Mizutani, Shu-hei, Mori, Ayumi, Nishio, Nobuhiro, Kidokoro, Hiroyuki, Yasui, Yoshihiro, Takahashi, Yoshiyuki, Sato, Yoshiaki, Shiraki, Anna, Ueda, Kazuto, Ando, Shotaro, Nagai, Noriko, Aoshima, Tsutomu, Suzuki, Michio, Kubota, Tetsuo, Suzuki, Motomasa, Doi, Satoru, Fukumi, Daichi, Sugiyama, Yuichiro, Morishita, Masafumi, Nishimura, Naoko, Takagi, Mizuki, Kurahashi, Hirokazu, Takeuchi, Yohei, Kuraishi, Kenji, Shinohara, Osamu, Kawabe, Takashi, Watanabe, Nobuhiro, Hasegawa, Shinji, Muto, Taichiro, Kido, Shinji, Hara, Shinya, Hoshino, Shin

“…Abstract Background Mitigation measures implemented during the coronavirus disease 2019 (COVID-19) pandemic remarkably reduced the incidence of infectious…”
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Administration of Bone Marrow-Derived Mononuclear Cells Contributed to the Reduction of Hypoxic-Ischemic Brain Injury in Neonatal Rats by Sato, Yoshiaki, Ueda, Kazuto, Kondo, Taiki, Hattori, Tetsuo, Mikrogeorgiou, Alkisti, Sugiyama, Yuichiro, Suzuki, Toshihiko, Yamamoto, Michiro, Hirata, Hitoshi, Hirakawa, Akihiro, Nakanishi, Keiko, Tsuji, Masahiro, Hayakawa, Masahiro

“…Perinatal hypoxic-ischemia (HI) causes neonatal death and permanent neurological deficits. Cell therapy using various cell sources has been recently identified…”
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Mesenchymal stem/stromal cells stably transduced with an inhibitor of CC chemokine ligand 2 ameliorate bronchopulmonary dysplasia and pulmonary hypertension by Suzuki, Toshihiko, Sato, Yoshiaki, Yamamoto, Hidenori, Kato, Taichi, Kitase, Yuma, Ueda, Kazuto, Mimatsu, Haruka, Sugiyama, Yuichiro, Onoda, Atsuto, Saito, Shigeki, Takahashi, Yoshiyuki, Nakayama, Takayuki, Hayakawa, Masahiro

“…Perinatal bronchopulmonary dysplasia (BPD) is defined as lung injury in preterm infants caused by various factors, resulting in serious respiratory dysfunction…”
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A Novel Treatment with Stem Cells from Human Exfoliated Deciduous Teeth for Hypoxic-Ischemic Encephalopathy in Neonatal Rats by Kitase, Yuma, Sato, Yoshiaki, Ueda, Kazuto, Suzuki, Toshihiko, Mikrogeorgiou, Alkisti, Sugiyama, Yuichiro, Matsubara, Kohki, Tsukagoshi Okabe, Yuka, Shimizu, Shinobu, Hirata, Hitoshi, Yukawa, Hiroshi, Baba, Yoshinobu, Tsuji, Masahiro, Takahashi, Yoshiyuki, Yamamoto, Akihito, Hayakawa, Masahiro

“…Recently, cell therapy has been developed as a novel treatment for perinatal hypoxic-ischemic encephalopathy (HIE), which is an important cause of neurological…”
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Safety and tolerability of a Muse cell-based product in neonatal hypoxic-ischemic encephalopathy with therapeutic hypothermia (SHIELD trial) by Sato, Yoshiaki, Shimizu, Shinobu, Ueda, Kazuto, Suzuki, Toshihiko, Suzuki, Sakiko, Miura, Ryosuke, Ando, Masahiko, Tsuda, Kennosuke, Iwata, Osuke, Muramatsu, Yukako, Kidokoro, Hiroyuki, Hirakawa, Akihiro, Hayakawa, Masahiro

“…Hypoxic-ischemic encephalopathy (HIE), associated with high mortality and neurological sequelae, lacks established treatment except therapeutic hypothermia…”
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